Overview

Dr. Ruth McPherson’s research is centered on the discovery and functional analysis of genetic variants linked to cardiovascular disease and its metabolic precedents, including lipid traits and obesity.

The goals of the laboratory are to develop a comprehensive and integrated understanding of the genetic and molecular etiology of complex phenotypes, with a focus on obesity and coronary artery disease (CAD). This entails simultaneous application of a number of methodologies, including rigorous clinical and metabolic phenotyping, genetics, tissue-specific gene expression, integrative genomics, and functional assays.