Bourke, Michael

Overview 

Dr. Michael Bourke practices Cardiac Anesthesiology and Critical Care Medicine at the University of Ottawa Heart Institute. In 1995, he was appointed Medical Director of the Cardiac Surgery Intensive Care Unit and served continuously in that role until April 2009.

Dr. Bourke is Assistant Professor at the University of Ottawa, where he lectures regularly in the Physics, Respiratory and Cardiovascular Core Programs of the Department of Anesthesiology, and also in the Critical Care Training Program.

Background 

Dr. Bourke completed his medical training at the University of Ottawa in 1975. He initially completed Family Medicine training (CCFP) in 1977, and then completed his Anesthesiology specialty as a Fellow of the Royal College of Physicians and Surgeons of Canada (FRCPC) in 1980.

After a clinical fellowship at The Ottawa Hospital (Civic Campus) in 1980, Dr. Bourke joined the Department of Anesthesia at The Ottawa Hospital (Civic Campus) and soon joined the Division of Cardiac Anesthesiology at the Heart Institute (1981). From 1980 until 2002, he directed the Physics and Fluids Core Program, Department of Anesthesiology, University of Ottawa. Between 1980 and 1988, he was Co-Director of the Chronic Pain Clinic at The Ottawa Hospital (Civic Campus). He also provided anesthesia for pediatric cardiac surgery at the Heart Institute before the Pediatric Program at the Children’s Hospital of Eastern Ontario was developed. He is Chairman of the University of Ottawa Heart Institute Peri-operative Database Unit. He was an initial member and continues to be a member of the Pulmonary Thromboendarterectomy Program .

Research & Clinical Interests 

Dr. Bourke’s areas of expertise and research, in addition to Cardiac Anesthesia and Critical Care, include artificial heart technology and the development of left ventricular assist devices , cardiac transplantation, pulmonary thromboendarterectomy, database development (Critical Care and Automated Anesthesia Database systems), intra-operative and critical care monitoring systems, treatment of post-operative hypertension, sympathetic innervation of the heart, congenital heart disease, and treatment of post-cardiopulmonary bypass shivering and chronic pain.

Publications 

LATEST PUBLICATIONS

  • Kotrec M, Williams K, Lefèvre I, Bedoya E, Mesana TG, Bourke M, Rubens FD. Sildenafil prior to thromboendarterectomy for chronic thromboembolic pulmonary hypertension, submitted to Journal of Cardiovascular Pharmacology and Therapeutics.
  • Boodhwani M, Nathan HJ, Mesana TG, Rubens FD; Cardiotomy Investigators (includes Bourke ME). Effects of shed mediastinal blood on cardiovascular and pulmonary function: a randomized, double-blind study. Ann Thorac Surg 2008 Oct;86(4):1167-1173.
  • Chan V, Kulik A, Bourke ME, Mesana TG, Ruel M. Clopidogrel is safe early after on- and off-pump coronary artery bypass surgery. Journal of Cardiac Surgery 2007 Nov-Dec;22(6):493-497.
  • Rubens FD, Bourke M, Hynes M, Nicholson D, Kotrec M, Boodhwani M, Ruel M, Dennie CJ, Mesana T. Surgery for chronic thromboembolic pulmonary hypertension: inclusive experience from a national referral center. Ann Thorac Surg 2007 Mar;83(3):1075-1081.

PAPERS IN REFEREED JOURNALS

  • Dupuis, J.E., Bourke, M.E. et al: "Pancuronium versus Vecuronium for Treatment of Shivering Patients after Cardiac Surgery" CJA Annual Meeting Supplement, Vol. 38, No 4, Part II, May 1991.
  • DeLima, L.G.R, Wynands, J.E., Nathan, J.H., Adam, J., Bourke, M.: The Adequacy of Oxygen Delivery Can be Predicted by Monitoring SV02 If V02 Is Known. Anesthesiolgoy V 77, No. 3A, Sep 1992
  • Nathan, H.J., Bourke, M.E. et al: Intravenous Nifedipine to Treat Hypertension After Coronary Artery Revascularization Surgery. A Comparison With Sodium Nitroprusside, Anesthesia and Analgesia, V 74, pp 809-17, 1992.
  • DeLima LGR, Wynands JE, Bourke ME, Walley VM.: Catheter-induced pulmonary artery false aneurysm and rupture: Case report and review. JCVA V8, No. 1 (February), 1994:pp 70-75
  • Dupuis JY, Nathan HJ, DeLima L, Wynands JE, Russell GN, Bourke M. Pancuronium or Vecuronium of Shivering after Cardiac Surgery. Anesth Analg 1994;79:472-81.
  • Mussivand T, Szurmak Z, Rajagopalan K, Robichaud R, Hum A, Holmes K, MacLean G, Hendry P, Masters RG, Bourke M, Lavallée G, Mueller R, Blohon R, Keaney M, Walley V, Royale A, King M, Keon WJ: Development of a Totally Implantable Ventricular Assist Device. Abstract presented at the American Society of Artificial Internal Organs, 1994.
  • Steinmetz O, Bedard P, Prefontaine M, Bourke M: Uterine tumor in the heart. Surgery 1996 Feb;119(2):226-9.
  • Bourke M: The patient with a pacemaker or related device. Can J Anaesth 1996 May;43(5 Pt 2):R24-41.
  • Hendry PJ, Masters RG, Keaney M, Bourke M, Mussivand T, Keon WJ: Evolution of an electrohydraulic ventricular assist device through in vivo testing. The EVAD Team. ASAIO Journal 1996 Sep-Oct;42(5):M350-4.
  • Walley VM, Bourke ME, Green M, Stinson WA, Veinot JP: Implantable Cardioverter-Defibrillators and the Pathologist: Comment and Cautionary Notes. J Forensic Sci 1998;43(5):969-973.
  • Hendry P, Masters RG, Ibrahim M, Bourke M, Keaney M, Kilborn S, Keon W, Mussivand T: In vivo evaluation of an intrathoracic ventricular assist device. [Journal Article] ASAIO Journal. 45(3):123-6, 1999 May-Jun.
  • Rubens F, Wells P, Bencze S, Bourke M: Surgical treatment of chronic thromboembolic pulmonary hypertension. Can Respir J 2000;7(1):49-57
  • Rubens FD, Sabloff M, Wells PS, Bourke M: Use of recombinant-hirudin in pulmonary thromboendarterectomy. [Journal Article] Annals of Thoracic Surgery. 69(6):1942-3, 2000 Jun.
  • Ruel MA. Wang F. Bourke ME. Dupuis JY. Robblee JA. Keon WJ. Rubens FD.:Is tranexamic acid safe in patients undergoing coronary endarterectomy?. Annals of Thoracic Surgery. 71(5):1508-11, 2001 May.
  • Hendry PJ. Mussivand TV. Masters RG. Bourke ME. Guiraudon GM. Holmes KS. Day KD. Keon WJ. The HeartSaver left ventricular assist device: an update. Annals of Thoracic Surgery. 71(3 Suppl):S166-70; discussion S183-4, 2001 Mar.
  • Dupuis JY. Wang F. Nathan H. Lam M. Grimes S. Bourke M. The cardiac anesthesia risk evaluation score: a clinically useful predictor of mortality and morbidity after cardiac surgery. (Comment in: Anesthesiology. 2001 Feb; 94 (2):191-3) Anesthesiology. 94(2):194-204, 2001 Feb.
  • Bourke ME, Healy JS, Pacemakers, Recent developments and directions, Current Opinion in Anesthesiology. December 2002, 15:681-686.
  • Kulik A, Ruel M, Bourke ME, et al, Postoperative naproxen after coronary artery bypass surgery: a double-blind randomized controlled trial. European Journal of Cardio-Thoracic Surgery , V 26, PP 694-70, October 2004
  • Rubens, FD, Lavalee ,G, Ruel MA, Mesana,T, Bourke, M. Delayed thrombin generation with hirudin anticoagulation during prolonged cardiopulmonary bypass. Ann Thorac Surg. 2005 Jan;79(1):334-6.
  • Veena Guru, MD,a Geoffrey M. Anderson,a Stephen E. Fremes, MD,a Gerald T. O’Connor, PhD,b Frederick L. Grover, MD,cJack V. Tu, MD, PhD,a and the Canadian CABG Surgery Quality Indicator Consensus Panel (inc. Bourke ME) The identification and development of Canadian coronary artery bypass graft surgery quality indicators. The Journal of Thoracic and Cardiovascular Surgery, V130(5) 2005 pp 1257.e1-e11
  • Rubens MD1, Michael Bourke MD2, Mark Hynes2, Donna Nicholson2 Marian Kotrec MD1, Marc Ruel MD1,3, Thierry Mesana MD1 , Surgery for Chronic Thromboembolic Pulmonary Hypertension – Inclusive Experience from a National Referral Center Fraser D Annals of Thoracic Surgery. 83(3):1075-81, 2007 Mar
  • Kulik A. Rubens FD. Gunning D. Bourke ME. Mesana TG. Ruel M. Radial artery graft treatment with phenoxybenzamine is clinically safe and may reduce perioperative myocardial injury.[see comment]. [Evaluation Studies. Journal Article] Annals of Thoracic Surgery. 83(2):502-9, 2007 Feb.
  • Chan V, Kulik A, Bourke ME, Mesana TG, Ruel M. Clopidogrel is safe early after on- and off-pump coronary artery bypass surgery. Journal of Cardiac Surgery 2007 Nov-Dec 22(6):493-497.
  • Boodhwani M, Nathan HJ, Mesana TG, Rubens FD; Cardiotomy Investigators (includes Bourke ME). Effects of shed mediastinal blood on cardiovascular and pulmonary function: a randomized, double-blind study. Ann Thorac Surg 2008 Oct;86(4):1167-1173.
  • Kotrec M, Williams K, Lefèvre I, Bedoya E, Mesana TG, Bourke M, Rubens FD. Sildenafil prior to thromboendarterectomy for chronic thromboembolic pulmonary hypertension, submitted to Journal of Cardiovascular Pharmacology and Therapeutics.

ABSTRACTS

  • Nathan, H., Bourke, M.E., et al: "A Continuous Intravenous Nifedipine Infusion for the Control of Hypertension Following Coronary Artery Surgery: Pharmacokinetics and Pharmacodynamics" Abstract, Canadian Cardiovascular Society Annual Meeting 1986
  • Nathan, H., Bourke, M.E. et al: Is Intravenous Nifedipine a Safe and Effective Treatment for Hypertension Following Coronary Artery Surgery? A Comparison with Sodium Nitroprusside Abstract, Society of Cardiovascular Anesthesiologists 10th Annual Meeting, 1988
  • Dupuis, J.E., Bourke, M.E. et al: "Does the Choice of Pancuronium or Vecuronium Matter in the Treatment of Shivering Patients after Cardiac Surgery?" SCA 13th Annual Meeting, May 1991
  • DeLima LGR, Wynands JE, Nathan HJ, Hynes MS, Dupuis JY, Bourke ME, Russell GN.: Accuracy of mixed venous blood oxygen saturation (SVO2) monitoring to detect critical oxygen delivery in patients following hypothermic cardiopulmonary bypass. CJA meeting supplement, V39, No. 5(II), pp A28, May '92.
  • Watson DC, Ooi DS, Bourke M. Evaluation of Mallinckrodt's GEM Premier Sensor System for pH, Blood Gases, Electrolytes and Hematocrit. Abstract at the XV International Congress of Clinical Chemistry, November 14-19, 1993, Melbourne Australia.
  • Bryson G, Mundi C, Dupuis JY, Bourke ME.: Can Multifactorial Classifications Predict Outcome After Cardiac Surgery in Patients with Preoperative Renal Dysfunction? Can J Anaesth 1994/41:5/pp A13.
  • Ibrahim M, Hendry P, Masters R, Bourke M, Keaney M, Kilborn M, Mueller R, Keon WJ, Mussivand T, Cardiovascular Devices Division, Ottawa Heart Institute: Recovery of calves with ventricular tachycardia/fibrillation (VT/VF) by a LVAD. ASAIO Journal, Vol. 44, 1998. (Abstract).
  • Hendry P, Ibrahim M, Masters R, Bourke M, Keaney M, Kilborn S, Mueller R, Keon WJ, Mussivand T, Cardiovascular Devices Division, Ottawa Heart Institute: Should cardiopulmonary bypass be avoided when implanting VAD s in a bovine model? ASAIO Journal, Vol. 44, 1998. (Abstract).
  • Mussivand T, Hendry P, Masters RG, Ibrahim M, Bourke M, Keaney M, Keon WJ, Ho C, Cardiovascular Devices Division, Ottawa Heart Institute: Thirty day in vivo evaluation of the heart saver ventricular assist device. ASAIO Journal, Vol. 44, 1998. (Abstract).
  • Hendry P, Masters R, Ibrahim M, Bourke M, Keaney M, Kilborn S, Mueller R, Keon WJ, Mussivand T, Cardiovascular Devices Division, Ottawa Heart Institute: In vivo evaluation of an intrathoracic ventricular assist device. ASAIO Journal, Vol. 44, 1998. (Abstract).
  • Ooi DS, Isotalo PA, Donnelly JG, Nathan HJ, Bourke ME: Clearance of plasma creatine kinase (CK), CK-MB, troponin l (cTnl) and T (cTnT) following coronary bypass surgery. Clin Chem 1999;45:A142
  • Rubens FD, Wells P, Bencze S, Bourke M: Surgery for chronic thromboembolic pulmonary hypertension: The UOHI Experience. Can J Cardiol 1999;15(Suppl D): Abs 141
  • Ruel M, Wang F, Bourke M, Dupuis J-Y, Rubens FD, Nichol G, Keon WJ: Operative outcome of high-risk patients referred to a quaternary cardiac surgery centre. Can J Cardiol 1999;15(Suppl D): Abs 342
  • Davies RA, Haddad H, Bourke M, Runstedler B, Dafoe D, Bennett R, Struthers C, Hendry P, Masters R, Mesana T, Mussivand T, Keon W. Assessment of Revesibility of Refractory Pulmonary Hypertension before Heart Transplantation with Nitric Oxide. Can J Cardiol 2002:18(Suppl B): Abs 386
  • Rubens FD, Bourke M, Hynes M, Mesana T. Surgery for chronic thromboembolic pulmonary hypertension: A Canadian perspective. Can J Cardiol 2002:18(Suppl B): Abs
  • Chapter 2 ‘Basic Physics Applied to Anaesthesia’ in ANESTESIA GENERALE E SPECIALE, Principi Procedure Tecniche, A cura di E. Romano, UTET, Torino – Italia (ANAESTHESIA, Principles Procedures Techniques, 2nd Edition , E. Romano, Editor-in-Chief, UTET, Torino – Italy) ; 2004.

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