Hibbert, Benjamin

Overview 

Benjamin Hibbert, MD, PhD, is an Interventional Cardiologist and Director of the Vascular Biology and Experimental Medicine Laboratory. He is also Assistant Professor in the Department of Medicine at the University of Ottawa. 

Background 

Dr. Hibbert earned his Doctorate in Medicine in 2006, followed by an Internal Medicine residency at the University of Ottawa. He subsequently went on to complete his Cardiology training and the Clinician Investigator Program while obtaining his PhD in Biochemistry – both at the University of Ottawa Heart Institute. Finally, he completed a fellowship in Interventional Cardiology from 2013-2015 with an interest in structural left atrial procedures (ASD & PFO closure, LAA closure, PTMV and Mitraclip). He joined on staff at the University of Ottawa Heart Institute in 2015.

Research & Clinical Interests 

Clinical

Dr. Hibbert’s clinical interests include both clinical and basic science research projects with a goal of performing truly translational research. His outcome based research has been performed clinically in patients undergoing percutaneous coronary interventions or structural heart disease procedures. Topics of interest include biomarker development, adjuvant pharmacotherapy (antiplatelets, antithrombotics etc.) and impact of device selection on clinical outcomes.

Research

Dr. Hibbert’s laboratory focuses on mechanisms involved in pathologic arterial remodeling in the development of transplant vasculopathy, in-stent restenosis, and atherosclerosis - with a goal of identifying therapeutic targets.

Publications 

See current publications list at PubMed.

Selected publications:

  1. Hibbert, B., Hayley,B., Beanlands, R.S., Le May, M., Davies, R., So, D., Marquis, J.F., Labinaz,M., Froeschl, M., O’Brien, E.R., Burwash, I., Pourdjabbar, A., Simard, T.,Atkins, H., Glover, C. (2014) G-CSFtherapy for STEM Cell Mobilization following anterior wall MyocardialInfarction: the CAPITAL STEM MI Randomized Trial. CMAJ.186(11):E427-34.
  2. Hibbert, B.,Lavoie, J., Ma, X., Seibert, T., Raizman, J., Simard, T., Chen, Y.X., Filion,L., Stewart, D.J., O’Brien, E.R. (2014)Glycogen Synthase Kinase-3β Inhibition Decreases Endothelial Progenitor CellApoptosis via Cathepsin B to Enhance Therapeutic Progenitor Cell Therapy inPatients with Diabetes. Diabetes. 63(4):1410-21.
  3. Ma, X., Hibbert, B.*(shared first author),McNulty, M., Hu, T., Zhao, X., Ramirez, F.D., Simard, T., Seibert, T., Wells,D.J., de Belleroche, J.S., O’Brien, E.R. (2014)Heat shock protein 27 improves arterial repair: a potential role for vascularendothelial growth factor-mediated enhancement of endothelial progenitor cells.FASEB. 28(2): 594-602.
  4. Hibbert, B., Maze,R., Pourdjabbar, A., Simard, T., Ramirez, F.D., Blondeau, M., Labinaz, M.,Dick, A., Glover, C., Froeschl, M., Marquis, J.F., So, D.Y.F., Le May, M.R. (2014) A Comparative PharmacodynamPatients UndergoingPrimary PCI: the CAPITAL RELOAD Study. PLoSONE. 9(3):e92078.
  5. Hibbert, B.,Simard, T., Ramirez, D., Maze, R., Wilson, K.R.,Hawken, S., O’Brien, E.R. (2013) Effect of Statin Therapy onCirculating Endothelial Progenitor Cells: a Systematic Review of Randomized Clinical Trials. Journal of Cardiovascular Pharmacology 62(5): 491-6.
  6. Seibert, T.A., Hibbert, B., Chen, Y.X., Rayner, K.,Simard, T., Hu, T., Cuerrier, C.M., Zhao, X., Wells, D.J., de Belleroche, J.,Chow, B.J., Wilson, K.R., Hawken, S., O’Brien, E.R. (2013). Serum Heat Shock Protein 27 Levels represent a PotentialTherapeutic Target for Atherosclerosis: Observations from a Human Cohort and Treatment of Female Mice. Journal of the American College of Cardiology 62(16):1446-54.
  7. Ramirez, F.D., Hibbert, B.* (shared first author),Simard, T., Pourdjabbar, A., Wilson, K., Hibbert, R., Kazmi, M., Hawken, S.,Ruel, M., Labinaz, M., O’Brien, E.R. (2012)Natural history and management of aortocoronary saphenous vein graft aneurysms:a systematic review of published cases. Circulation 126(18): 2248-56.
  8. Hibbert, B.,MacDougall, A., Blondeau, M., O’Brien, E.R., So, D.Y.F., Labinaz, M., Dick, A.,Glover, C., Froeschl, M., Marquis, J., Wells, G.A., Le May, M.R. (2012) Bivalirudin for primarypercutaneous coronary interventions: outcome assessment in the Ottawa STEMIregistry. Circulation: Cardiovascular Interventions 5(6): 805-12.
  9. Simard, T., Hibbert, B.* (shared first author),Pourdjabbar, A., Wilson, K.R., Hawken, S., O’Brien, E.R. (2012) Percutaneous Coronary Intervention With or Without On-SiteCoronary Artery Bypass Surgery: a Systematic Review and Meta-Analysis. Int Journal Cardiol 167(1): 197-204.
  10. Hibbert, B.,Simard, T. Wilson, K.R., Hawken, S., Wells, G.A., Le May, M.R., So, D.Y.,Glover, C.A., Froeschl, M., Marquis, J., Labinaz, M., Dick, A., O’Brien, E.R. (2012) Radial versus Femoral ArteryApproach for Coronary Angiography in the Extremely Obese. Journal of the American College of Cardiology: Cardiovascular Interventions 5(8): 819-26.

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