Sun, Louise

Overview 

Dr. Louise Sun is a cardiac anesthesiologist at the University of Ottawa Heart Institute (UOHI) and an assistant professor of anesthesiology and epidemiology at the University of Ottawa. Dr. Sun also holds a full status adjunct scientist position at the Institute for Clinical Evaluative Sciences (ICES).  Dr. Sun is the director of Cardiocore Big Data Research Unit and Team Soleil at UOHI.

Background 

Dr. Sun received her medical degree from McMaster University in 2008. She completed her anesthesiology residency at the University of Ottawa in 2013 and received her Master of Science in epidemiology from Harvard University that same year. As a trainee, Dr. Sun received several awards, including the Canadian Anesthesiologists’ Society Residents Research Awards (2012 and 2013), and is published in high impact journals such as The Journal of the American Medical Association (JAMA) Internal Medicine, and Anesthesiology. Dr. Sun completed a combined clinical and research fellowship in cardiac anesthesia at the Toronto General Hospital in December 2014 and joined the UOHI in early 2015. She was appointed to ICES faculty the following year. In September 2019, Dr. Sun was elected as a Fellow of the American Heart Association.

Dr. Sun sits on the Heart and Stroke Foundation (H&S) Scientific Review Committee and served on the grant review panel for the Dutch Organization for Health Research and Development. She collaborates with CorHealth Ontario on the Task Force for Cardiac Surgery Reports Risk Adjustment, and with regional health authorities to evaluate current models of cardiac health care delivery. Dr. Sun is an active committee/task force member of the American Heart Association and the Society of Cardiovascular Anesthetists.

Dr. Sun’s research is focused on leveraging big data to tackle key issues in health care delivery, and outcomes for patients with heart failure and/or undergoing cardiovascular interventions. Her program is funded by the Canadian Institutes of Health Research (CIHR), the Ministry of Health and Long-Term Care, the University of Ottawa, and the UOHI ORACLE Strategic Plan. Her work has garnered global interest. Her study on the sex differences in outcomes of heart failure, published in the Canadian Medical Association Journal (2018), generated world-wide media attention, with interviews and editorial in the US and European news networks. Her paper on the association between intraoperative hypotension and stroke was featured as “Article of the Month” (Anesthesiology 2018); her work on identifying critical intraoperative blood pressure thresholds in association with acute kidney injury was ranked in the top three most cited articles in Anesthesiology (2017), and top 20 most cited articles in Anesthesiology (2016). She has been invited to provide cardiovascular health-related commentaries on national channels such as CTV News.

Dr. Sun was a recipient of the uOttawa Junior Faculty Excellence Award (2019) for her outstanding contributions to research, education and professionalism in the Department of Anesthesia and Pain Medicine; and the UOHI Dr. Robert Roberts Award of Research Excellence (2019) for her high-impact paper on sex differences in heart failure outcomes published in the Canadian Medical Association Journal (CMAJ). She was amongst a panel of cardiovascular specialists selected to showcase the accomplishments of women in cardiovascular medicine and science at the Canadian Cardiovascular Congress in 2019. She was a finalist for the American Heart Association’s Vivien Thomas Young Investigator Award (2018) and was named a top reviewer for the Annals of Internal Medicine (2015 and 2018).

Research & Clinical Interests 

Clinical

  • Heart failure
  • Ventricular assist devices and heart transplantation
  • Hemodynamic monitoring

Research

Dr. Sun’s research interests include:

  • heart failure epidemiology, disability consequences and health service utilization.
  • impact of cardiac surgery and percutaneous interventions on long-term outcomes and quality of life.
  • risk prediction and precision medicine, focusing on sex/gender and patient engagement.
Publications 

See current publications list at ORCID.

Selected publications:

  • Johnston A, Mesana TG, Lee DS, Bader Eddeen A, Sun LY. Sex Differences in Long-Term Survival After Major Cardiac Surgery: A Population-Based Cohort Study. Journal of the American Heart Association. 2019 Sep 3;8(17):e013260.
  • Ruel M, Sun LY. Postoperative Use of Calcium-Channels Blockers in Patients with a Radial Artery Graft: Do We Now Have a Definitive Answer? Journal of the American College of Cardiology, 2019. May 14;73(18):2307-2309.
  • Sun LY, Kimmoun A, Takagi K, Liu PP, Bader Eddeen A, Mebazaa A. Ethnic Differences in Acute
  • Heart Failure Outcomes in Ontario. International Journal of Cardiology, 2019. Sept 15;291:177-182.
  • Sun LY, Tu JV, Lee DS, Beanlands RS, Ruel M, Austin PC, Bader Eddeen A, Liu PP. Disability-Free Survival After Coronary Artery Bypass Grafting in Women and Men with Heart Failure and Preserved versus Reduced Ejection Fraction. BMJ Open Heart. 2018. Nov 5;5(2):e000911.
  • Sun LY, Chung AM, Farkouh M, Van Diepen S, Weinberger J, Bourke M, Ruel M. Defining a Perioperative Hypotension Threshold in Association with Stroke in Cardiac Surgery. Anesthesiology. 2018 Sep;129(3):440-447.
  • Sun LY, Tu JV, Coutinho T, Turek M, Rubens F, McDonnell L, Tulloch H, Bader Eddeen, A. Mielniczuk LM. Sex Differences in Heart Failure Outcomes in an Ambulatory, Population-Based Cohort. CMAJ. 2018 Jul 16;190(28):E848-E854.
  • Tran DTT, Tu JV, Dupuis JY, Bader Eddeen A, Sun LY. Association of Frailty and Long-Term Survival in Patients Undergoing Coronary Artery Bypass Grafting. Journal of the American Heart Association. 2018 Jul 20;7(15). pii: e009882.
  • Sun LY, Tu JV, Bader Eddeen A, Liu PP. Long-Term Survival After Coronary Artery Bypass Grafting in Men and Women with Heart Failure and Preserved vs Reduced Ejection Fraction. Journal of the American Heart Association. 2018;7(e008902).
  • Sun LY, Wijeysundera DN, Tait G, Beattie WS. Association of Intraoperative Hypotension with Acute Kidney Injury after Elective Noncardiac Surgery. Anesthesiology. 2015 Sept;123(3): 515-23.
  • Sun LY, Gershon AS, Ko DT, Thilen SR, Yun L, Beattie WS, Wijeysundera DN. Trends of Pulmonary Function Testing before Non-Cardiothoracic Surgery in a Population-Based Cohort. JAMA Internal Medicine. 2015 Aug;175(8):1410-2.

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