Recent Publications

2021

May

Annabi, M.-S., Zhang, B., Bergler-Klein, J., Dahou, A., Burwash, I. G., Guzzetti, E., Ong, G., Tastet, L., Orwat, S., Baumgartner, H., Bartko, P. E., Koschutnik, M., Mascherbauer, J., Mundigler, G., Cavalcante, J., Ribeiro, H. B., Rodès-Cabau, J., Pibarot, P., & Clavel, M.-A. (2021). Usefulness of the B-Type Natriuretic Peptides in Low Ejection Fraction, Low-Flow, Low-Gradient Aortic Stenosis Results from the TOPAS Multicenter Prospective Cohort Study. Structural Heart. https://doi.org/10.1080/24748706.2021.1900630 

Balaji, A., Kelsey, L. J., Majeed, K., Schultz, C. J., & Doyle, B. J. (2021). Coronary artery segmentation from intravascular optical coherence tomography using  deep capsules. Artificial Intelligence in Medicine, 116, 102072. https://doi.org/10.1016/j.artmed.2021.102072 

Boodhwani, M. (2021). Commentary: Aortic valve repair—from art to science. JTCVS Techniques. https://doi.org/10.1016/j.xjtc.2021.04.002 

Byron-Alhassan, A., Collins, B., Bedard, M., Quinlan, B., Le May, M., Duchesne, L., Osborne, C., Wells, G., Smith, A. M., & Tulloch, H. E. (2021). Cognitive Dysfunction after Out-of-Hospital Cardiac Arrest: Rate of Impairment and  Clinical Predictors. Resuscitation. https://doi.org/10.1016/j.resuscitation.2021.05.002 

Cassidy, C. E., Beck, A. J., Conway, A., Demery Varin, M., Laur, C., Lewis, K. B., Ramage, E. R., Nguyen, T., Steinwender, S., Ormel, I., Stratton, L., & Shin, H. D. (2021). Using an integrated knowledge translation or other research partnership approach in  trainee-led research: a scoping review protocol. BMJ Open, 11(5), e043756. https://doi.org/10.1136/bmjopen-2020-043756 

Chen, J. L., Schipani, A., Schuch, C. P., Lam, H., Swardfager, W., Thiel, A., & Edwards, J. D. (2021). Does Cathodal vs. Sham Transcranial Direct Current Stimulation Over Contralesional Motor Cortex Enhance Upper Limb Motor Recovery Post-stroke? A Systematic Review and Meta-analysis. Frontiers in Neurology, 12. https://doi.org/10.3389/fneur.2021.626021 

Davies, B., Bartels, K., Hathaway, J., Xu, F., Roberts, J. D., Tadros, R., Green, M. S., Healey, J. S., Simpson, C. S., Sanatani, S., Steinberg, C., Gardner, M., Angaran, P., Talajic, M., Hamilton, R., Arbour, L., Seifer, C., Fournier, A., Joza, J., … Laksman, Z. W. M. (2021). Variant Re-interpretation in Survivors of Cardiac Arrest with Preserved Ejection Fraction (CASPER Registry) by Clinicians and Clinical Commercial Laboratories. Circulation. Genomic and Precision Medicine. https://doi.org/10.1161/CIRCGEN.120.003235 

deKemp, R., Juneau, D., Wells, G., & Beanlands, R. (2021). Response to Poitrasson-Rivière and Murthy. In Journal of nuclear cardiology : official publication of the American Society of  Nuclear Cardiology. https://doi.org/10.1007/s12350-021-02639-1 

Dewidar, O., Riddle, A., Ghogomu, E., Hossain, A., Arora, P., Bhutta, Z. A., Black, R. E., Cousens, S., Gaffey, M. F., Mathew, C., Trawin, J., Tugwell, P., Welch, V., & Wells, G. A. (2021). PRIME-IPD SERIES Part 1. The PRIME-IPD tool promoted verification and standardization of study datasets retrieved for IPD meta-analysis. Journal of Clinical Epidemiology. https://doi.org/10.1016/j.jclinepi.2021.05.007 

Dewidar, O., Riddle, A., Ghogomu, E., Hossain, A., Arora, P., Bhutta, Z. A., Black, R. E., Cousens, S., Mathew, C., Trawin, J., Tugwell, P., Welch, V., & Wells, G. A.(2021). PRIME-IPD SERIES Part 3. The PRIME-IPD tool fills a gap in guidance for preparing  IPD for analysis. Journal of Clinical Epidemiology. https://doi.org/10.1016/j.jclinepi.2021.05.001 

Gharibeh, L., Hosoyama, K., Glineur, D., Shaw, R. E., Lapierre, H., Ruel, M., & Grau, J. B. (2021). Comparative Analysis Following Implementation of Two Types of Y-Composite  Multiarterial Revascularization Strategies at a Single Academic Institution. Journal of the American Heart Association, 10(10), e020002. https://doi.org/10.1161/JAHA.120.020002 

Grace, S. L., Gallagher, J., & Tulloch, H. (2021). The psychological component of cardiac rehabilitation drives benefits achieved. European Journal of Preventive Cardiology. https://doi.org/10.1093/eurjpc/zwab040 

Guo, M. H., Appoo, J. J., Wells, G. A., Chu, M., Ouzounian, M., Fortier, J., & Boodhwani, M. (2021). Protocol for a randomised controlled trial for Treatment in Thoracic Aortic  Aneurysm: Surgery versus Surveillance (TITAN: SvS). BMJ Open, 11(5), e052070. https://doi.org/10.1136/bmjopen-2021-052070 

Guzmán-Soto, I., McTiernan, C., Gonzalez-Gomez, M., Ross, A., Gupta, K., Suuronen, E. J., Mah, T.-F., Griffith, M., & Alarcon, E. I. (2021). Mimicking biofilm formation and development: Recent progress in in vitro and in vivo biofilm models. IScience, 24(5). https://doi.org/10.1016/j.isci.2021.102443 

Han, H.-C., Hawkins, N. M., Pearman, C. M., Birnie, D. H., & Krahn, A. D. (2021). Epidemiology of cardiac implantable electronic device infections: incidence and risk  factors. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of  the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. https://doi.org/10.1093/europace/euab042 

Hu, L.-H., Miller, R. J. H., Sharir, T., Commandeur, F., Rios, R., Einstein, A. J., Fish, M. B., Ruddy, T. D., Kaufmann, P. A., Sinusas, A. J., Miller, E. J., Bateman, T. M., Dorbala, S., Di Carli, M., Liang, J. X., Eisenberg, E., Dey, D., Berman, D. S., & Slomka, P. J. (2021). Prognostically safe stress-only single-photon emission computed tomography  myocardial perfusion imaging guided by machine learning: report from REFINE SPECT. European Heart Journal. Cardiovascular Imaging, 22(6), 705–714. https://doi.org/10.1093/ehjci/jeaa134 

Ismailani, U. S., Munch, M., Mair, B. A., & Rotstein, B. H. (2021). Interrupted aza-Wittig reactions using iminophosphoranes to synthesize  (11)C-carbonyls. Chemical Communications (Cambridge, England), 57(43), 5266–5269. https://doi.org/10.1039/d1cc01016f 

Kaoutskaia, A., Shurrab, M., Amit, G., Parkash, R., Exner, D., Toal, S., Sterns, L., Sarrazin, J.-F., Chauhan, V., Sultan, O., Nair, G., Deyell, M., Macle, L., Klassen, S., Glover, B., & Crystal, E. (2021). Canadian national electrophysiology ablation registry report 2011-2016. BMC Health Services Research, 21(1), 435. https://doi.org/10.1186/s12913-021-06441-0 

Li, T., Wu, J., Liu, J., Sun, W., Qi, C., Liu, B., Wells, G. A., & Wang, J. (2021). Protocol for the Acute Myocardial Infarction Study in Northeastern China (AMINoC): a  real-world prospective cohort study. BMJ Open, 11(5), e042936. https://doi.org/10.1136/bmjopen-2020-042936 

Makhdoum, A., Dhingra, N. K., Kirubaharan, A., Eikelboom, R., Luc, J., Dagher, O., Bierer, J., Cartier, A., Vaillancourt, O., Vo, T. X., Forgie, K., Bisleri, G., Yau, T. M., Verma, S., & Yanagawa, B. (2021). Ticagrelor use and practice patterns among Canadian cardiac surgeons. Journal of Cardiac Surgery. https://doi.org/10.1111/jocs.15636 

McIsaac, D. I., Montroy, J., Gagne, S., Johnson, C., Ernst, J., Halman, S., Oake, J., Chan, J., Madden, S., Feng, S., Moody, M., Simard, C. G., Taljaard, M., Foster, M., Fergusson, D. A., & Lalu, M. M. (2021). Implementation of the Canadian Cardiovascular Society guidelines for perioperative  risk assessment and management: an interrupted time series study. Canadian Journal of Anaesthesia = Journal Canadien d’anesthésie. https://doi.org/10.1007/s12630-021-02026-x 

Mulloy, A., Siouti, L., Beauchesne, L., Chan, K. L., Vulesevic, B., Ascah, K., Countinho, T., Promislow, S., Burwash, I. G., & Messika-Zeitoun, D. (2021). Clinical implications of left atrial size adjustment: Impact of obesity. Archives of Cardiovascular Diseases. https://doi.org/10.1016/j.acvd.2021.01.007 

Nakashima, T., Cheniti, G., Takagi, T., Vlachos, K., Goujeau, C., André, C., Krisai, P., Ramirez, F. D., Pintican, G., Kamakura, T., Nakatani, Y., Surget, E., Roux, J.-R., Meillet, V., Carapezzi, A., Tixier, R., Chauvel, R., Pambrun, T., Duchateau, J., … Sacher, F. (2021). Local abnormal ventricular activity detection in scar-related VT: Microelectrode  versus conventional bipolar electrode. Pacing and Clinical Electrophysiology : PACE. https://doi.org/10.1111/pace.14253 

Nakashima, T., Nakatani, Y., Ramirez, F. D., Cheniti, G., Jaïs, P., & Sacher, F. (2021). Varying physiologic ventricular resynchronization with changes in atrial rhythm in a  patient with a right-sided accessory pathway and right bundle branch block. Journal of Electrocardiology, 66, 122–124. https://doi.org/10.1016/j.jelectrocard.2021.04.012 

Nantsios, A., Vo, T. X., & Ruel, M. (2021). Commentary: External stenting of saphenous vein grafts—ReinVESTing to achieve best returns in coronary artery bypass grafting. Journal of Thoracic and Cardiovascular Surgery. https://doi.org/10.1016/j.jtcvs.2021.04.032 

Qin, Z., Zhang, L., Zasloff, M. A., Stewart, A. F. R., & Chen, H.-H. (2021). Ketamine’s schizophrenia-like effects are prevented by targeting PTP1B. Neurobiology of Disease, 155, 105397. https://doi.org/10.1016/j.nbd.2021.105397 

Rahmim, A., Uribe, C., MacKay, A., & Wells, G. (2021). Obituary for Dr. Anna Celler. In European journal of nuclear medicine and molecular imaging. https://doi.org/10.1007/s00259-021-05252-z 

Rahmouni, K., & Bernier, P.-L. (2021). Current Management of Anomalous Aortic Origin of a Coronary Artery: A Pan-Canadian  Survey. World Journal for Pediatric & Congenital Heart Surgery, 12(3), 387–393. https://doi.org/10.1177/2150135121999030 

Rahmouni, K., Deng, M., Gharibeh, L., Elmistekawy, E., Grau, J., Mesana, T., & Chan, V. (2021). Systematic Approach to the Calcified Mitral Valve Apparatus at Time of Mitral Valve  Replacement. The Annals of Thoracic Surgery. https://doi.org/10.1016/j.athoracsur.2021.03.109 

Reed, J. L., Terada, T., Way, K. L., Vidal-Almela, S., Pipe, A. L., & Risom, S. S. (2021). Exercise Targets in the 2020 CCS Guidelines for the Management of Patients with  Atrial Fibrillation. In The Canadian journal of cardiology. https://doi.org/10.1016/j.cjca.2021.04.019 

Reid, R. D., Wooding, E. A., Blanchard, C. M., Moghei, M., Harris, J., Proulx, G.-A., Prince, S. A., Mullen, K. A., Ghisi, G. M., Krahn, M., Chessex, C., Pipe, A. L.,Mark, A. E., & Grace, S. L. (2021). A Randomized Controlled Trial of an Exercise Maintenance Intervention in Men and  Women After Cardiac Rehabilitation (ECO-PCR Trial). The Canadian Journal of Cardiology, 37(5), 794–802. https://doi.org/10.1016/j.cjca.2020.10.015 

Rinfret, S., Jahan, I., McKenzie, K., Dendukuri, N., Bainey, K. R., Mansour, S., Natarajan, M., Ybarra, L. F., Chong, A.-Y., Bérubé, S., Breton, R., Curtis, M. J., Rodés-Cabau, J., Amlani, S., Bagherli, A., Ball, W., Barolet, A., Beydoun, H. K., Brass, N., … Brophy, J. M. (2021). COVID-19 pandemic and coronary angiography for ST-elevation myocardial infarction,  use of mechanical support and mechanical complications in Canada; a Canadian Association of Interventional Cardiology national survey. CJC Open. https://doi.org/10.1016/j.cjco.2021.04.017 

Rubens, F. D., Virani, A., Coylewright, M., Sathananthan, J., & Wood, D. (2021). Balancing patient-centered care and evidence-based medicine in patients needing coronary revascularization. Journal of Thoracic and Cardiovascular Surgery. https://doi.org/10.1016/j.jtcvs.2021.03.116 

Ryzhaya, N., Cermakova, L., Trinder, M., Ruel, I., Coutinho, T., Genest, J., & Brunham, L. R. (2021). Sex Differences in the Presentation, Treatment, and Outcome of Patients With  Familial Hypercholesterolemia. In Journal of the American Heart Association (p. e019286). https://doi.org/10.1161/JAHA.120.019286 

Sengupta, P. P., Shrestha, S., Kagiyama, N., Hamirani, Y., Kulkarni, H., Yanamala, N., Bing, R., Chin, C. W. L., Pawade, T. A., Messika-Zeitoun, D., Tastet, L., Shen, M., Newby, D. E., Clavel, M.-A., Pibarot, P., & Dweck, M. R. (2021). A Machine-Learning Framework to Identify Distinct Phenotypes of Aortic Stenosis  Severity. JACC. Cardiovascular Imaging. https://doi.org/10.1016/j.jcmg.2021.03.020 

Simpson, F. C., McTiernan, C. D., Islam, M. M., Buznyk, O., Lewis, P. N., Meek, K. M., Haagdorens, M., Audiger, C., Lesage, S., Gueriot, F.-X., Brunette, I., Robert, M.-C., Olsen, D., Koivusalo, L., Liszka, A., Fagerholm, P., Gonzalez-Andrades, M., & Griffith, M. (2021). Collagen analogs with phosphorylcholine are inflammation-suppressing scaffolds for  corneal regeneration from alkali burns in mini-pigs. Communications Biology, 4(1), 608. https://doi.org/10.1038/s42003-021-02108-y 

Small, G. R., & Chow, B. J. W. (2021). Imaging in CABG Patients. Current Treatment Options in Cardiovascular Medicine, 23(7). https://doi.org/10.1007/s11936-021-00922-5 

Steinberg, C., Davies, B., Mellor, G., Tadros, R., Laksman, Z. W., Roberts, J. D., Green, M., Alqarawi, W., Angaran, P., Healey, J., Sanatani, S., Leather, R., Seifer, C., Fournier, A., Duff, H., Gardner, M., McIntyre, C., Hamilton, R., Simpson, C. S., & Krahn, A. D. (2021). Short-coupled ventricular fibrillation represents a distinct phenotype among latent  causes of unexplained cardiac arrest: a report from the CASPER registry. European Heart Journal. https://doi.org/10.1093/eurheartj/ehab275 

Sunner, M., Qiu, F., Manoragavan, R., Roifman, I., Tam, D. Y., Fremes, S. C., Sun, L., Rahal, M., Woodward, G., Austin, P. C., & Wijeysundera, H. C. (2021). Predictors of cumulative cost for patients with severe aortic stenosis referred for  surgical or transcatheter aortic valve replacement: a population-based study in Ontario, Canada. European Heart Journal. Quality of Care & Clinical Outcomes, 7(3), 265–272. https://doi.org/10.1093/ehjqcco/qcaa094 

Vo, T. X., & Boodhwani, M. (2021, May). A clampless and atraumatic technique for surgical preclosure of peripheral arteries. In Multimedia manual of cardiothoracic surgery : MMCTS (Vol. 2021). https://doi.org/10.1510/mmcts.2021.030 

Wanschel, A. C. B. A., Moretti, A. I. S., & Ouimet, M. (2021). Editorial: Covid-19 Mechanisms on Cardio-Vascular Dysfunction: From Membrane Receptors to Immune Response. In Frontiers in cardiovascular medicine (Vol. 8, p. 686495). https://doi.org/10.3389/fcvm.2021.686495 

Weingarten, B. R., Tran, D. T. T., Mahaffey, R., & Sohmer, B. (2021). Tranexamic acid for primary elective off-pump coronary artery bypass grafting  surgery. In Canadian journal of anaesthesia = Journal canadien d’anesthésie. https://doi.org/10.1007/s12630-021-02013-2 

Yanofsky, R., Sancho, C., Gasbarrino, K., Zheng, H., Doonan, R. J., Jaunet, F., Steinmetz-Wood, S., Veinot, J. P., Lai, C., & Daskalopoulou, S. S. (2021). Expression of Resistin, Chemerin, and Chemerin’s Receptor in the Unstable Carotid  Atherosclerotic Plaque. Stroke, STROKEAHA120030228. https://doi.org/10.1161/STROKEAHA.120.030228 

Zhang, L., Qin, Z., Sharmin, F., Lin, W., Ricke, K. M., Zasloff, M. A., Stewart, A. F. R., & Chen, H.-H. (2021). Tyrosine phosphatase PTP1B impairs presynaptic NMDA receptor-mediated plasticity in  a mouse model of Alzheimer’s disease. Neurobiology of Disease, 156, 105402. https://doi.org/10.1016/j.nbd.2021.105402

April

Ahmady, E., Blais, A., & Burgon, P. G. (2021). Muscle Enriched Lamin Interacting Protein (Mlip) Binds Chromatin and Is Required for Myoblast Differentiation. Cells, 10(3). https://doi.org/10.3390/cells10030615 

Alqarawi, W., Grose, E., Ramirez, F. D., Sikora, L., Golian, M., Nair, G. M., Nery, P. B., Klein, A., Davis, D., Green, M. S., Redpath, C. J., Birnie, D. H., Burwash, I., & Sadek, M. M. (2021). Prevalence of Left Atrial Appendage Thrombus in Patients Anticoagulated With Direct Oral Anticoagulants: Systematic Review and Meta-analysis. CJC Open. https://doi.org/10.1016/j.cjco.2020.12.012 

Arangalage, D., Cattan, L., Eugène, M., Cimadevilla, C., Monney, P., Iung, B., Brochet, E., Burwash, I. G., Vahanian, A., & Messika-Zeitoun, D. (2021). Prognostic Value of Peak Exercise Systolic Pulmonary Arterial Pressure in  Asymptomatic Primary Mitral Valve Regurgitation. Journal of the American Society of Echocardiography : Official Publication of the  American Society of Echocardiography. https://doi.org/10.1016/j.echo.2021.04.009 

Bagchi, A. K., Malik, A., Akolkar, G., Zimmer, A., Belló-Klein, A., De Angelis, K., Jassal, D. S., Fini, M. A., Stenmark, K. R., & Singal, P. K. (2021). Study of ER stress and apoptotic proteins in the heart and tumor exposed to  doxorubicin. Biochimica et Biophysica Acta. Molecular Cell Research, 1868(7), 119039. https://doi.org/10.1016/j.bbamcr.2021.119039 

Bateman, T. M., Heller, G. V, Beanlands, R., Calnon, D. A., Case, J., deKemp, R., Gordon DePuey, E., Di Carli, M., Guler, E. C., Murthy, V. L., Rosenblatt, J., Sher, R., Slomka, P., & Ruddy, T. D. (2021). Practical guide for interpreting and reporting cardiac PET measurements of  myocardial blood flow: an Information Statement from the American Society of Nuclear Cardiology, and the Society of Nuclear Medicine and Molecular Imaging. Journal of Nuclear Cardiology : Official Publication of the American Society of  Nuclear Cardiology, 28(2), 768–787. https://doi.org/10.1007/s12350-021-02552-7 

Boczar, K. E., Liu, P., Chong, A. Y., So, D., Dowlatshahi, D., Rayner, K., & Beanlands, R. (2021). Observational Cross-Sectional Study of Inflammatory Markers After Transient Ischemic Attacks, Acute Coronary Syndromes, and Vascular Stroke Events. CJC Open. https://doi.org/10.1016/j.cjco.2020.12.020 

Chen, Y.-X., Shi, C., Deng, J., Diao, C., Maarouf, N., Rosin, M., Shrivastava, V., Hu, A. A., Bharadwa, S., Adijiang, A., Ulke-Lemee, A., Gwilym, B., Hellmich, A., Malozzi, C., Batulan, Z., Dean, J. L. E., Ramirez, F. D., Liu, J., Gerthoffer, W. T., & O’Brien, E. R. (2021). HSP25 Vaccination Attenuates Atherogenesis via Upregulation of LDLR Expression, Lowering of PCSK9 Levels and Curbing of Inflammation. Arteriosclerosis, Thrombosis, and Vascular Biology, ATVBAHA121315933. https://doi.org/10.1161/ATVBAHA.121.315933 

Chow, B. J. W., Yam, Y., Alenazy, A., Crean, A. M., Clarkin, O., Hossain, A., & Small, G. R. (2021). Are Training Programs Ready for the Rapid Adoption of CCTA?: CBME in CCTA. JACC. Cardiovascular Imaging. https://doi.org/10.1016/j.jcmg.2021.01.040 

Clifford, C. R., Le May, M., Chow, A., Boudreau, R., Fu, A. Y. N., Barry, Q., Chong, A. Y., & So, D. Y. F. (2021). Delays in ST-Elevation Myocardial Infarction Care During the COVID-19 Lockdown: An Observational Study. CJC Open. https://doi.org/10.1016/j.cjco.2020.12.009 

Clifford, C. R., Jung, R. G., Hibbert, B., Chong, A. Y., Lordkipanidzé, M., Tanguay, J.-F., & So, D. Y. F. (2021). Dual antiplatelet therapy (PEGASUS) vs. dual pathway (COMPASS): a head-to-head in  vitro comparison. Platelets, 1–6. https://doi.org/10.1080/09537104.2021.1904134 

deKemp, R., Juneau, D., Wu, K. Y., Wells, G., Ruddy, T., & Beanlands, R. (2021). On the roles of reproducibility, ethics, and statistical modeling in medical  research. In Journal of nuclear cardiology : official publication of the American Society of  Nuclear Cardiology. https://doi.org/10.1007/s12350-021-02592-z 

Elmistekawy, E., Nair, V., & Rubens, F. D. (2021). Skin cancer at median sternotomy scar. Asian Cardiovascular & Thoracic Annals, 2184923211006864. https://doi.org/10.1177/02184923211006864 

Garcia, S., Dehghani, P., Grines, C., Davidson, L., Nayak, K. R., Saw, J., Waksman, R., Blair, J., Akshay, B., Garberich, R., Schmidt, C., Ly, H. Q., Sharkey, S., Mercado, N., Alfonso, C. E., Misumida, N., Acharya, D., Madan, M., Hafiz, A. M., … Chong, A.-Y. … Henry, T. D. (2021). Initial Findings From the North American COVID-19 Myocardial Infarction Registry. Journal of the American College of Cardiology, 77(16), 1994–2003. https://doi.org/10.1016/j.jacc.2021.02.055 

Gharibeh, L., Ferrari, G., Ouimet, M., & Grau, J. B. (2021). Conduits’ Biology Regulates the Outcomes of Coronary Artery Bypass Grafting. JACC: Basic to Translational Science, 6(4), 388–396. https://doi.org/10.1016/j.jacbts.2020.11.015 

Guo, M. H., & Rubens, F. D. (2021). Commentary: Never let semantics get in the way of a good idea. JTCVS Techniques. https://doi.org/10.1016/j.xjtc.2021.03.001 

Hu, M., Jana, S., Kilic, T., Wang, F., Shen, M., Winkelaar, G., Oudit, G. Y., Rayner, K., Zhang, D.-W., & Kassiri, Z. (2021). Loss of TIMP4 (Tissue Inhibitor of Metalloproteinase 4) Promotes Atherosclerotic  Plaque Deposition in the Abdominal Aorta Despite Suppressed Plasma Cholesterol Levels. Arteriosclerosis, Thrombosis, and Vascular Biology, ATVBAHA120315522. https://doi.org/10.1161/ATVBAHA.120.315522 

Lalande, K., Greenman, P. S., Bouchard, K., Johnson, S. M., & Tulloch, H. (2021). The Healing Hearts Together Randomized Controlled Trial and the COVID-19 Pandemic: A  Tutorial for Transitioning From an In-Person to a Web-Based Intervention. Journal of Medical Internet Research, 23(4), e25502. https://doi.org/10.2196/25502 

Lee, F., & Mielniczuk, L. M. (2021). Pulmonary Hypertension Due to Left Heart Disease-A Practical Approach to Diagnosis  and Management. The Canadian Journal of Cardiology, 37(4), 572–584. https://doi.org/10.1016/j.cjca.2020.11.003 

Lemay, S., Massot, M., Philippon, F., Belzile, D., Turgeon, P. Y., Beaudoin, J., Laliberté, C., Fortin, S., Dion, G., Milot, J., Trottier, M., Gosselin, J., Charbonneau, É., Birnie, D. H., & Sénéchal, M. (2021). Ten Questions Cardiologists Should Be Able to Answer About Cardiac Sarcoidosis: Case-Based Approach and Contemporary Review. CJC Open, 3(4), 532–548. https://doi.org/10.1016/j.cjco.2020.11.022 

Massalha, S., & Slart, R. H. J. A. (2021). Anderson-Fabry disease: Worthy to in-SPECT the nerves? In Journal of nuclear cardiology : official publication of the American Society of  Nuclear Cardiology (Vol. 28, Issue 2, pp. 650–652). https://doi.org/10.1007/s12350-019-01787-9 

McDonald, M., Virani, S., Chan, M., Ducharme, A., Ezekowitz, J. A., Giannetti, N., Heckman, G. A., Howlett, J. G., Koshman, S. L., Lepage, S., Mielniczuk, L., Moe, G. W., O’Meara, E., Swiggum, E., Toma, M., Zieroth, S., Anderson, K., Bray, S. A., Clarke, B., … Yip, A. M. C. (2021). CCS/CHFS Heart Failure Guidelines Update: Defining a New Pharmacologic Standard of  Care for Heart Failure With Reduced Ejection Fraction. In The Canadian journal of cardiology (Vol. 37, Issue 4, pp. 531–546). https://doi.org/10.1016/j.cjca.2021.01.017 

Muser, D., Nucifora, G., Muser, D., Nucifora, G., Pieroni, M., Castro, S. A., Casado Arroyo, R., Maeda, S., Benhayon, D. A., Liuba, I., Sadek, M., Magnani, S., Enriquez, A., Liang, J. J., Sassone, B., Desjardins, B., Dixit, S., Deo, R., Garcia, F. C., … Santangeli, P. (2021). Prognostic Value of Nonischemic Ringlike Left Ventricular Scar in Patients With  Apparently Idiopathic Nonsustained Ventricular Arrhythmias. Circulation, 143(14), 1359–1373. https://doi.org/10.1161/CIRCULATIONAHA.120.047640 

O’Neill, C. D., Vidal-Almela, S., Tulloch, H. E., Coutinho, T., Prince, S. A., & Reed, J. L. (2021). COVID-19 pandemic: Inequities and inequalities to exercise and their consequences on  the physical and mental health of women with cardiovascular disease; Recommendations on how to address the needs of women. Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquee, Nutrition et Métabolisme. https://doi.org/10.1139/apnm-2020-1094 

Pereira, N. L., Rihal, C., Lennon, R., Marcus, G., Shrivastava, S., Bell, M. R., So, D., Geller, N., Goodman, S. G., Hasan, A., Lerman, A., Rosenberg, Y., Bailey, K., Murad, M. H., & Farkouh, M. E. (2021). Effect of CYP2C19 Genotype on Ischemic Outcomes During Oral P2Y12 Inhibitor Therapy: A Meta-Analysis. JACC: Cardiovascular Interventions, 14(7), 739–750. https://doi.org/10.1016/j.jcin.2021.01.024 

Pipe, A. L. (2021). Vaping, Smoking Cessation, and Harm Reduction? Look Before You Leap. In The Canadian journal of cardiology. https://doi.org/10.1016/j.cjca.2021.02.002 

Rahmouni, K., & Rubens, F. D. (2021). Commentary: The Goldilocks annuloplasty: Not too big, not too small. Journal of Thoracic and Cardiovascular Surgery. https://doi.org/10.1016/j.jtcvs.2021.02.030 

Rozencwajg, S., Blet, A., Lamer, A., Boisson, M., Clavier, T., & Abou-Arab, O. (2021). SARS-CoV-2 vaccination efficacy on hospitalisation and variants. In Anaesthesia, critical care & pain medicine (p. 100867). https://doi.org/10.1016/j.accpm.2021.100867 

Rubens, F. D., Ngu, J., Malvea, A., Samuels, S. J., & Burwash, I. G. (2021). Early Midterm Results After Valve Replacement With Contemporary Pericardial Prostheses for Severe Aortic Stenosis. Annals of Thoracic Surgery. https://doi.org/10.1016/j.athoracsur.2020.08.029 

Sabag, A., Keating, S. E., Way, K. L., Sultana, R. N., Lanting, S. M., Twigg, S. M., & Johnson, N. A. (2021). The association between cardiorespiratory fitness, liver fat and insulin resistance  in adults with or without type 2 diabetes: a cross sectional-analysis. BMC Sports Science, Medicine & Rehabilitation, 13(1), 40. https://doi.org/10.1186/s13102-021-00261-9 

Shahinian, J. H., Chong, A. Y., & Glineur, D. (2021). Cutting-Edge Coronary Imaging Guiding CABG. In Innovations (Philadelphia, Pa.) (p. 15569845211008162). https://doi.org/10.1177/15569845211008162 

Simard, T., Motazedian, P., Dhaliwal, S., Di Santo, P., Jung, R. G., Ramirez, F. D., Labinaz, A., Short, S., Parlow, S., Joseph, J., Rasheed, A., Rockley, M., Marbach, J., Domecq, M.-C., Russo, J. J., Chong, A.-Y., Beanlands, R. S., & Hibbert, B. (2021). Revisiting the Evidence for Dipyridamole in Reducing Restenosis: A Systematic Review  and Meta-analysis. Journal of Cardiovascular Pharmacology, 77(4), 450–457. https://doi.org/10.1097/FJC.0000000000000976 

Son, J. E., Dou, Z., Kim, K.-H., Wanggou, S., Cha, V. S. Bin, Mo, R., Zhang, X., Chen, X., Ketela, T., Li, X., Huang, X., & Hui, C.-C. (2021). Irx3 and Irx5 in Ins2-Cre(+) cells regulate hypothalamic postnatal neurogenesis and  leptin response. Nature Metabolism. https://doi.org/10.1038/s42255-021-00382-y 

Sun, L. Y., Eddeen, A. B., & Mesana, T. G. (2021). Disability-free survival after major cardiac surgery: a population-based  retrospective cohort study. CMAJ Open, 9(2), E384–E393. https://doi.org/10.9778/cmajo.20200096 

Terada, T., Almela, S. V., Tulloch, H. E., Pipe, A. L., & Reed, J. L. (2021). Cardiac Rehabilitation Following Percutaneous Coronary Intervention Is Associated  With Superior Psychological Health and Quality of Life in Males but Not in Females. Journal of Cardiopulmonary Rehabilitation and Prevention. https://doi.org/10.1097/HCR.0000000000000597 

Welsh, R. C., Cantor, W. J., Traboulsi, M., Schampaert, E., & Le May, M. (2021). Primary Percutaneous Coronary Intervention and Application of the Pharmacoinvasive  Approach Within ST-Elevation Myocardial Infarction Care Networks: CJC Supplement - 40 Years of Innovation in Interventional Cardiology in Canada. The Canadian Journal of Cardiology. https://doi.org/10.1016/j.cjca.2021.02.023

March

Alqarawi, W., Dewidar, O., Tadros, R., Roberts, J. D., Steinberg, C., MacIntyre, C. J., Laksman, Z. W. M., Green, M. S., Nair, G., Wells, G., & Krahn, A. D. (2021). Defining Idiopathic Ventricular Fibrillation: A Systematic Review of Diagnostic  Testing Yield in Apparently Unexplained Cardiac Arrest. Heart Rhythm. https://doi.org/10.1016/j.hrthm.2021.03.030

Birnie, D. H., Nair, V., & Veinot, J. P. (2021). Cardiac Sarcoidosis and Giant Cell Myocarditis: Actually, 2 Ends of the Same  Disease? In Journal of the American Heart Association (Vol. 10, Issue 6, p. e020542). https://doi.org/10.1161/JAHA.121.020542

Colella, T. J. F., Hardy, M., Hart, D., Price, J. A. D., Sarfi, H., Mullen, K.-A., Mulvagh, S., & Norris, C. M. (2021). The Canadian Women’s Heart Health Alliance Atlas on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women—Chapter 3: Patient Perspectives. CJC Open, 3(3), 229–235. https://doi.org/10.1016/j.cjco.2020.11.020

Corrales-Medina, V. F., deKemp, R. A., Chirinos, J. A., Zeng, W., Wang, J., Waterer, G., Beanlands, R. S. B., & Dwivedi, G. (2021). Persistent lung inflammation after clinical resolution of community-acquired  pneumonia as measured by (18)FDG-PET/CT. Chest. https://doi.org/10.1016/j.chest.2021.02.048

Di Santo, P., Simard, T., Wells, G. A., Jung, R. G., Ramirez, F. D., Boland, P., Marbach, J. A., Parlow, S., Kyeremanteng, K., Coyle, D., Fergusson, D., Russo, J. J., Chong, A.-Y., Froeschl, M., So, D. Y., Dick, A., Glover, C., Labinaz, M., Hibbert, B., & Le May, M. (2021). Transradial Versus Transfemoral Access for Percutaneous Coronary Intervention in  ST-Segment-Elevation Myocardial Infarction: A Systematic Review and Meta-Analysis. Circulation. Cardiovascular Interventions, 14(3), e009994. https://doi.org/10.1161/CIRCINTERVENTIONS.120.009994

Elliott, J., Wells, G. A., & Coyle, D. (2021). The Continued Need for Transparent Evidence on the Cost Effectiveness of Drugs for  Rare Diseases. In PharmacoEconomics. https://doi.org/10.1007/s40273-021-01007-8

Fernando, S. M., Mathew, R., Hodgson, C. L., Fan, E., & Brodie, D. (2021). Media Portrayals of the Acute Respiratory Distress Syndrome. Chest. https://doi.org/10.1016/j.chest.2021.03.017

Hansom, S. P., Alqarawi, W., Birnie, D. H., Golian, M., Nery, P. B., Redpath, C. J., Klein, A., Green, M. S., Davis, D. R., Sheppard-Perkins, E., Ramirez, F. D., Nair, G. M., & Sadek, M. M. (2021). High-power, short-duration atrial fibrillation ablation compared with a conventional  approach: Outcomes and reconnection patterns. Journal of Cardiovascular Electrophysiology. https://doi.org/10.1111/jce.14989

Kelly, S. E., Campbell, D., Duhn, L. J., Giddens, K., Gillis, A. M., AbdelWahab, A., Nault, I., Raj, S. R., Lockwood, E., Basta, J., Doucette, S., Wells, G. A., & Parkash, R. (2021). Remote Monitoring of Cardiovascular Implantable Electronic Devices in Canada: Survey of Patients and Device Health Care Professionals. CJC Open. https://doi.org/10.1016/j.cjco.2020.11.010

Kim, K.-H., & Backx, P. H. (2021). Understanding the Role of Iroquois Homeobox Transcription Factor 5 (IRX5) in Cardiac  Function: Getting to the (Human) Heart of the Matter. Cardiovascular Research. https://doi.org/10.1093/cvr/cvab098

Lauck, S. B., Lewis, K. B., Borregaard, B., & de Sousa, I. (2021). “What is the right decision for me?” Integrating patient perspectives through shared  decision-making for valvular heart disease therapy. The Canadian Journal of Cardiology. https://doi.org/10.1016/j.cjca.2021.02.022

Lewis, K. B., Graham, I. D., Boland, L., & Stacey, D. (2021). Writing a compelling integrated discussion: a guide for integrated discussions in  article-based theses and dissertations. International Journal of Nursing Education Scholarship, 18(1). https://doi.org/10.1515/ijnes-2020-0057

McIsaac, D. I., Fottinger, A., Sucha, E., & McDonald, B. (2021). Association of frailty with days alive at home after cardiac surgery: a  population-based cohort study. British Journal of Anaesthesia. https://doi.org/10.1016/j.bja.2021.02.011

Miller, R. J. H., Sharir, T., Otaki, Y., Gransar, H., Liang, J. X., Einstein, A. J., Fish, M. B., Ruddy, T. D., Kaufmann, P. A., Sinusas, A. J., Miller, E. J., Bateman, T. M., Dorbala, S., Di Carli, M., Tamarappoo, B. K., Dey, D., Berman, D. S., & Slomka, P. J. (2021). Quantitation of Post-Stress Change in Ventricular Morphology Improves Risk  Stratification. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. https://doi.org/10.2967/jnumed.120.260141

Nantsios, A., & Rubens, F. D. (2021). Unexplained fever following DeBakey type I aortic dissection repair with woven  Dacron grafts. In Journal of cardiac surgery. https://doi.org/10.1111/jocs.15497

Nery, P. B., Nair, G. M., & Birnie, D. H. (2021). Letter to the Editor: Catheter Ablation of Low Voltage Areas for Persistent Atrial  Fibrillation: Procedural Outcomes using High-Density Voltage Mapping. In The Canadian journal of cardiology. https://doi.org/10.1016/j.cjca.2021.03.011

Nguyen, E. T., Bayanati, H., Bilawich, A.-M., Sanchez Tijmes, F., Lim, R., Harris, S., Dennie, C., & Oikonomou, A. (2021). Canadian Society of Thoracic Radiology/Canadian Association of Radiologists Clinical  Practice Guidance for Non-Vascular Thoracic MRI. Canadian Association of Radiologists Journal = Journal l’Association Canadienne Des  Radiologistes, 846537121998961. https://doi.org/10.1177/0846537121998961

Pearson, G. J., Thanassoulis, G., Anderson, T. J., Barry, A. R., Couture, P., Dayan, N., Francis, G. A., Genest, J., Grégoire, J., Grover, S. A., Gupta, M., Hegele, R. A., Lau, D., Leiter, L. A., Leung, A. A., Lonn, E., Mancini, G. B. J., Manjoo, P., McPherson, R., … Wray, W. (2021). 2021 Canadian Cardiovascular Society Guidelines for the Management of Dyslipidemia  for the Prevention of Cardiovascular Disease in the Adult. In The Canadian journal of cardiology. https://doi.org/10.1016/j.cjca.2021.03.016

Pereira, N. L., Rihal, C., Lennon, R., Marcus, G., Shrivastava, S., Bell, M. R., So, D., Geller, N., Goodman, S. G., Hasan, A., Lerman, A., Rosenberg, Y., Bailey, K., Murad, M. H., & Farkouh, M. E. (2021). Effect of CYP2C19 Genotype on Ischemic Outcomes During Oral P2Y(12) Inhibitor  Therapy: A Meta-Analysis. JACC. Cardiovascular Interventions. https://doi.org/10.1016/j.jcin.2021.01.024

Pottie, K., Magwood, O., Rahman, P., Concannon, T., Alonso-Coello, P., Jaramillo Garcia, A., Santesso, N., Thombs, B., Welch, V., Wells, G. A., Saad, A., Archibald, D., Grad, R., Moore, A., Ximena Rojas, M., Iorio, A., Pinto, N., Doull, M., Morton, R., … Tugwell, P. (2021). GRADE Concept Paper 1: Validating the “F.A.C.E” instrument using stakeholder  perceptions of feasibility, acceptability, cost, and equity in guideline implement. Journal of Clinical Epidemiology, 131, 133–140. https://doi.org/10.1016/j.jclinepi.2020.11.018

Rooprai, J., Boodhwani, M., Beauchesne, L., Chan, K.-L., Dennie, C., Wells, G. A., & Coutinho, T. (2021). Central Hypertension in Patients With Thoracic Aortic Aneurysms: Prevalence and  Association With Aneurysm Size and Growth. American Journal of Hypertension. https://doi.org/10.1093/ajh/hpaa183

Ross, A., Muñoz, M., Rotstein, B. H., Suuronen, E. J., & Alarcon, E. I. (2021). A low cost and open access system for rapid synthesis of large volumes of gold and  silver nanoparticles. Scientific Reports, 11(1), 5420. https://doi.org/10.1038/s41598-021-84896-1

Sedlakova, V., McTiernan, C., Cortes, D., Suuronen, E. J., & Alarcon, E. I. (2021). 3D Bioprinted Cardiac Tissues and Devices for Tissue Maturation. Cells, Tissues, Organs, 1–14. https://doi.org/10.1159/000512792

Wallis, J. W., Klein, R., Bradshaw, T. J., Catana, C., Hatt, M., Laforest, R., Liu, C., Mawlawi, O., McCall, K. C., Osborne, D. R., Tang, J., Wells, R. G., & Ghesani, M. (2021). Guidelines on Setting Up Stations for Remote Viewing of Nuclear Medicine and  Molecular Imaging Studies During COVID-19. Journal of Nuclear Medicine Technology, 49(1), 2–6. https://doi.org/10.2967/jnmt.120.261890

February

Blet, A., Deniau, B., Santos, K., van Lier, D. P. T., Azibani, F., Wittebole, X., Chousterman, B. G., Gayat, E., Hartmann, O., Struck, J., Bergmann, A., Antonelli, M., Beishuizen, A., Constantin, J.-M., Damoisel, C., Deye, N., Di Somma, S., Dugernier, T., François, B., … Mebazaa, A. (2021). Monitoring circulating dipeptidyl peptidase 3 (DPP3) predicts improvement of organ  failure and survival in sepsis: a prospective observational multinational study. Critical Care (London, England)25(1), 61. https://doi.org/10.1186/s13054-021-03471-2

Bourque, J. M., Hanson, C. A., Agostini, D., Bateman, T. M., Bax, J. J., Beanlands, R. S. B., Berman, D. S., Garcia, E. V, Heller, G. V, Knuuti, J., Tamaki, N., Udelson, J. E., & Maddahi, J. (2021). Assessing myocardial perfusion in suspected coronary artery disease: rationale and  design of the second phase 3, open-label multi-center study of flurpiridaz (F-18) injection for positron emission tomography (PET) imaging. Journal of Nuclear Cardiology : Official Publication of the American Society of  Nuclear Cardiology. https://doi.org/10.1007/s12350-021-02527-8

Cheskes, L., Krywenky, A., & Sadek, M. M. (2021). Just the facts: management of electrical storm and recurrent ICD shocks in the emergency department. Canadian Journal of Emergency Medicine. https://doi.org/10.1007/s43678-020-00049-9

Collins, R. L., Brand, H., Karczewski, K. J., Zhao, X., Alföldi, J., Francioli, L. C., Khera, A. V, Lowther, C., Gauthier, L. D., Wang, H., Watts, N. A., Solomonson, M., O’Donnell-Luria, A., Baumann, A., Munshi, R., Walker, M., Whelan, C. W., Huang, Y., Brookings, T., … McPherson, R. … Consortium, G. A. D. (2021). Author Correction: A structural variation reference for medical and population genetics (Nature, (2020), 581, 7809, (444-451), 10.1038/s41586-020-2287-8). Nature. https://doi.org/10.1038/s41586-020-03176-6

Cummings, B. B., Karczewski, K. J., Kosmicki, J. A., Seaby, E. G., Watts, N. A., Singer-Berk, M., Mudge, J. M., Karjalainen, J., Satterstrom, F. K., O’Donnell-Luria, A. H., Poterba, T., Seed, C., Solomonson, M., Alföldi, J., Alföldi, J., Armean, I. M., Banks, E., Bergelson, L., Cibulskis, K., …McPherson, R. … Consortium, G. A. D. (2021). Author Correction: Transcript expression-aware annotation improves rare variant interpretation (Nature, (2020), 581, 7809, (452-458), 10.1038/s41586-020-2329-2). Nature. https://doi.org/10.1038/s41586-020-03175-7

Ghofrani, H.-A., Gomez Sanchez, M.-A., Humbert, M., Pittrow, D., Simonneau, G., Gall, H., Grünig, E., Klose, H., Halank, M., Langleben, D., Snijder, R. J., Escribano Subias, P., Mielniczuk, L. M., Lange, T. J., Vachiéry, J.-L., Wirtz, H., Helmersen, D. S., Tsangaris, I., Barberá, J. A., … LIST, N. E. W. C. (2021). Riociguat treatment in patients with chronic thromboembolic pulmonary hypertension: Final safety data from the EXPERT registry. Respiratory Medicine178. https://doi.org/10.1016/j.rmed.2020.106220

Huang, J. W., Lahey, B., Clarkin, O. J., Kong, J., Clark, E., Kanji, S., McCudden, C., Akbari, A., J.W. Chow, B., Shabana, W., & Hiremath, S. (2021). A Systematic Review of the Effect of N-Acetylcysteine on Serum Creatinine and Cystatin C Measurements. Kidney International Reports6(2), 396–403. https://doi.org/10.1016/j.ekir.2020.11.018

Jenkins, D. J. A., Dehghan, M., Mente, A., Bangdiwala, S. I., Rangarajan, S., Srichaikul, K., Mohan, V., Avezum, A., Díaz, R., Rosengren, A., Lanas, F., Lopez-Jaramillo, P., Li, W., Oguz, A., Khatib, R., Poirier, P., Mohammadifard, N., Pepe, A., Alhabib, K. F., … Yusuf, S. (2021). Glycemic Index, Glycemic Load, and Cardiovascular Disease and Mortality. The New England Journal of Medicine. https://doi.org/10.1056/NEJMoa2007123

Juneau, D., & Pelletier-Galarneau, M. (2021). Assessment of myocardial inflammation post-infarct with PET/MRI: Getting into the  nitty-gritty. In Journal of nuclear cardiology : official publication of the American Society of  Nuclear Cardiology. https://doi.org/10.1007/s12350-021-02558-1

Jung, R. G., Di Santo, P., Clifford, C., Prosperi-Porta, G., Skanes, S., Hung, A., Parlow, S., Visintini, S., Ramirez, F. D., Simard, T., & Hibbert, B. (2021). Methodological quality of COVID-19 clinical research. Nature Communications12(1), 943. https://doi.org/10.1038/s41467-021-21220-5

Karczewski, K. J., Francioli, L. C., Tiao, G., Cummings, B. B., Alföldi, J., Wang, Q., Collins, R. L., Laricchia, K. M., Ganna, A., Birnbaum, D. P., Gauthier, L. D., Brand, H., Solomonson, M., Watts, N. A., Rhodes, D., Singer-Berk, M., England, E. M., Seaby, E. G., Kosmicki, J. A., …McPherson, R. … Consortium, G. A. D. (2021). Author Correction: The mutational constraint spectrum quantified from variation in 141,456 humans (Nature, (2020), 581, 7809, (434-443), 10.1038/s41586-020-2308-7). Nature. https://doi.org/10.1038/s41586-020-03174-8

Kendzerska, T., Zhu, D. T., Gershon, A. S., Edwards, J. D., Peixoto, C., Robillard, R., & Kendall, C. E. (2021). The Effects of the Health System Response to the COVID-19 Pandemic on Chronic  Disease Management: A Narrative Review. Risk Management and Healthcare Policy14, 575–584. https://doi.org/10.2147/RMHP.S293471

Klein, A., Shenasa, M., & Baranchuk, A. (2021). Social Risk Factors and Atrial Fibrillation. Cardiac Electrophysiology Clinics13(1), 165–172. https://doi.org/10.1016/j.ccep.2020.10.008

Kumar, S., Davis, J., Thibault, B., Mangat, I., Coutu, B., Bennett, M., Philippon, F., Sandhu, R., Sterns, L., Essebag, V., Nery, P., Wells, G., Yee, R., Exner, D., Krahn, A., & Parkash, R. (2021). Canadian Registry of Electronic Device Outcomes: remote monitoring outcomes in the  Abbott battery performance alert-a multicentre cohort. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of  the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. https://doi.org/10.1093/europace/euab025

Lewis, K. B., Harkness, K., Hummel, A., Leung, J., & MacIver, J. (2021). The relational dynamics of caregivers of patients with a left ventricular assist  device for destination-therapy: A qualitative investigation. Heart & Lung : The Journal of Critical Care50(3), 375–381. https://doi.org/10.1016/j.hrtlng.2021.01.008

Minikel, E. V, Karczewski, K. J., Martin, H. C., Cummings, B. B., Whiffin, N., Rhodes, D., Alföldi, J., Trembath, R. C., van Heel, D. A., Daly, M. J., Alföldi, J., Armean, I. M., Banks, E., Bergelson, L., Cibulskis, K., Collins, R. L., Connolly, K. M., Covarrubias, M., Cummings, B. B., …McPherson, R. … Consortium, G. A. D. (2021). Author Correction: Evaluating drug targets through human loss-of-function genetic variation (Nature, (2020), 581, 7809, (459-464), 10.1038/s41586-020-2267-z). Nature. https://doi.org/10.1038/s41586-020-03177-5

Nikpay, M., & McPherson, R. (2021). Convergence of biomarkers and risk factor trait loci of coronary artery disease at  3p21.31 and HLA region. NPJ Genomic Medicine6(1), 12. https://doi.org/10.1038/s41525-021-00174-z

Noda, T., Kamiya, K., Hamazaki, N., Nozaki, K., Ichikawa, T., Nakamura, T., Yamashita, M., Uchida, S., Maekawa, E., Reed, J. L., Yamaoka-Tojo, M., Matsunaga, A., & Ako, J. (2021). Prognostic value of cardio-hepatic-skeletal muscle syndrome in patients with heart  failure. Scientific Reports11(1), 3715. https://doi.org/10.1038/s41598-020-80641-2

Ouk, M., Wu, C.-Y., Rabin, J. S., Jackson, A., Edwards, J. D., Ramirez, J., Masellis, M., Swartz, R. H., Herrmann, N., Lanctôt, K. L., Black, S. E., & Swardfager, W. (2021). The use of angiotensin-converting enzyme inhibitors vs. angiotensin receptor  blockers and cognitive decline in Alzheimer’s disease: the importance of blood-brain barrier penetration and APOE ε4 carrier status. Alzheimer’s Research & Therapy13(1), 43. https://doi.org/10.1186/s13195-021-00778-8

Qureshi, S. H., & Ruel, M. (2021). Commentary: A long-lasting complication: Re-exploration for bleeding and its  negative correlation with long-term survival. In Seminars in thoracic and cardiovascular surgery. https://doi.org/10.1053/j.semtcvs.2020.12.025

Racey, M., MacFarlane, A. J., Carlson, S., Stark, K. D., Plourde, M., Field, C. J., Yates, A. A., Wells, G. A., Grantham, A., Bazinet, R. P., & Ma, D. W. L. (2021). Dietary Reference Intakes Based on Chronic Disease Endpoints: Outcomes from a case  study workshop for omega 3’s EPA and DHA. Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition et  Métabolisme. https://doi.org/10.1139/apnm-2020-0994

Rahmouni, K., & Rubens, F. D. (2021). Commentary: Multi-Arterial Grafting in Atrial Fibrillation: Pushing the envelope of  practicality? In Seminars in thoracic and cardiovascular surgery. https://doi.org/10.1053/j.semtcvs.2021.01.015

Rasheed, A., & Rayner, K. J. (2021). Macrophage Responses to Environmental Stimuli During Homeostasis and Disease. Endocrine Reviews. https://doi.org/10.1210/endrev/bnab004

Robichaud, S., Fairman, G., Vijithakumar, V., Mak, E., Cook, D. P., Pelletier, A. R., Huard, S., Vanderhyden, B. C., Figeys, D., Lavallée-Adam, M., Baetz, K., & Ouimet, M. (2021). Identification of novel lipid droplet factors that regulate lipophagy and  cholesterol efflux in macrophage foam cells. Autophagy, 1–19. https://doi.org/10.1080/15548627.2021.1886839

Rosenfeld, L. E., Chung, M. K., Harding, C. V, Spagnolo, P., Grunewald, J., Appelbaum, J., Sauer, W. H., Culver, D. A., Joglar, J. A., Lin, B. A., Jellis, C. L., Dickfeld, T.-M., Kwon, D. H., Miller, E. J., Cremer, P. C., Bogun, F., Kron, J., Bock, A., Mehta, D., …Birnie, D., … Estep, J. D. (2021). Arrhythmias in Cardiac Sarcoidosis Bench to Bedside: A Case-Based Review. Circulation. Arrhythmia and Electrophysiology14(2), e009203. https://doi.org/10.1161/CIRCEP.120.009203

Ruel, M. (2021). Commentary: Sternotomy for every cardiac surgery patient ain’t the future, so let’s  get going. In The Journal of thoracic and cardiovascular surgery. https://doi.org/10.1016/j.jtcvs.2021.01.096

Sadek, J., Moloo, H., Belanger, P., Nadeau, K., Aitken, D., Foss, K., Zwiep, T., McIsaac, D., Williams, L., Raiche, I., Musselman, R., & Mullen, K.-A. (2021). Implementation of a systematic tobacco treatment protocol in a surgical outpatient  setting: a feasibility study. Canadian Journal of Surgery. Journal Canadien de Chirurgie64(1), E51–E58. https://doi.org/10.1503/cjs.009919

Sarathy, K., Wells, G. A., Singh, K., Couture, E., Chong, A. Y., Rubens, F., Lordkipanidzé, M., Tanguay, J.-F., & So, D. (2021). Platelet Quiescence in Patients With Acute Coronary Syndrome Undergoing Coronary  Artery Bypass Graft Surgery. Journal of the American Heart Association, e016602. https://doi.org/10.1161/JAHA.120.016602

Simard, T., Alqahtani, F., Hibbert, B., Mamas, M. A., El-Hajj, S., Harris, A. H., Hohmann, S. F., & Alkhouli, M. (2021). Sex-specific in-hospital outcomes of transcatheter aortic valve replacement with  third generation transcatheter heart valves. Catheterization and Cardiovascular Interventions : Official Journal of the Society  for Cardiac Angiography & Interventions. https://doi.org/10.1002/ccd.29499

Stiell, I. G., Mielniczuk, L., Clark, H. D., Hebert, G., Taljaard, M., Forster, A. J., Wells, G. A., Clement, C. M., Brinkhurst, J., Brown, E. L., Nemnom, M.-J., & Perry, J. J. (2021). Interdepartmental program to improve outcomes for acute heart failure patients seen in the emergency department. Canadian Journal of Emergency Medicine. https://doi.org/10.1007/s43678-020-00047-x

Stiell, I. G., Sivilotti, M. L. A., Taljaard, M., Birnie, D., Vadeboncoeur, A., Hohl, C. M., McRae, A. D., Morris, J., Mercier, E., Macle, L., Brison, R. J., Thiruganasambandamoorthy, V., Rowe, B. H., Borgundvaag, B., Clement, C. M., Brinkhurst, J., Brown, E., Nemnom, M.-J., Wells, G. A., & Perry, J. J. (2021). A randomized, controlled comparison of electrical versus pharmacological cardioversion for emergency department patients with acute atrial flutter. Canadian Journal of Emergency Medicine. https://doi.org/10.1007/s43678-020-00067-7

Wairimu, F., Ward, N. C., Liu, Y., & Dwivedi, G. (2021). Cardiac transplantation in HIV positive patients: a narrative review. Journal of Acquired Immune Deficiency Syndromes (1999). https://doi.org/10.1097/QAI.0000000000002647

Wang, Q., Pierce-Hoffman, E., Cummings, B. B., Alföldi, J., Francioli, L. C., Gauthier, L. D., Hill, A. J., O’Donnell-Luria, A. H., Armean, I. M., Banks, E., Bergelson, L., Cibulskis, K., Collins, R. L., Connolly, K. M., Covarrubias, M., Daly, M. J., Donnelly, S., Farjoun, Y., Ferriera, S., … McPherson, R., … Consortium, G. A. D. (2021). Author Correction: Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes (Nature Communications, (2020), 11, 1, (2539), 10.1038/s41467-019-12438-5). Nature Communications12(1). https://doi.org/10.1038/s41467-021-21077-8

Whiffin, N., Armean, I. M., Kleinman, A., Marshall, J. L., Minikel, E. V, Goodrich, J. K., Quaife, N. M., Cole, J. B., Wang, Q., Karczewski, K. J., Cummings, B. B., Francioli, L., Laricchia, K., Guan, A., Alipanahi, B., Morrison, P., Baptista, M. A. S., Merchant, K. M., Armean, I. M., … McPherson, R., …Team, 23andMe Research. (2021). Author Correction: The effect of LRRK2 loss-of-function variants in humans (Nature Medicine, (2020), 26, 6, (869-877), 10.1038/s41591-020-0893-5). Nature Medicine. https://doi.org/10.1038/s41591-020-01185-6

Whiffin, N., Karczewski, K. J., Zhang, X., Chothani, S., Smith, M. J., Evans, D. G., Roberts, A. M., Quaife, N. M., Schafer, S., Rackham, O., Alföldi, J., O’Donnell-Luria, A. H., Francioli, L. C., Armean, I. M., Banks, E., Bergelson, L., Cibulskis, K., Collins, R. L., Connolly, K. M., … McPherson, R., … Consortium, G. A. D. (2021). Author Correction: Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals (Nature Communications, (2020), 11, 1, (2523), 10.1038/s41467-019-10717-9). Nature Communications12(1). https://doi.org/10.1038/s41467-021-21052-3

January

An, K. R., Luc, J. G. Y., Tam, D. Y., Dagher, O., Eikelboom, R., Bierer, J., Cartier, A., Vo, T. X., Vaillancourt, O., Forgie, K., Elbatarny, M., Gao, S. W., Whitlock, R., Lamba, W., Arora, R. C., Adams, C., & Yanagawa, B. (2021). Infective endocarditis secondary to injection drug use: A survey of Canadian cardiac surgeons. The Annals of Thoracic Surgery. https://doi.org/10.1016/j.athoracsur.2020.12.003

Chih, S., Wiefels, C. C., & Beanlands, R. S. B. (2021). PET Assessment of Cardiac Allograft Vasculopathy. Seminars in Nuclear Medicine. https://doi.org/10.1053/j.semnuclmed.2020.12.010

Cruz, S. A., Qin, Z., Ricke, K. M., Stewart, A. F. R., & Chen, H.-H. (2021). Neuronal protein-tyrosine phosphatase 1B hinders sensory-motor functional recovery and causes affective disorders in two different focal ischemic stroke models. Neural Regeneration Research16(1), 129–136. https://doi.org/10.4103/1673-5374.286970

Davis, M. K., Fine, N. M., Small, G. R., Connolly, K., Bosley, D., Zieroth, S., & Virani, S. A. (2021). Establishing a Cardiac Amyloidosis Clinic: A Practical Primer for Cardiologists. The Canadian Journal of Cardiology. https://doi.org/10.1016/j.cjca.2021.01.015

de Oliveira Brito, J. B., deKemp, R. A., & Ruddy, T. D. (2021). Evolving use of PET viability imaging. In Journal of nuclear cardiology : official publication of the American Society of  Nuclear Cardiology. https://doi.org/10.1007/s12350-020-02460-2

Deng, M., Elmistekawy, E., Mesana, T., & Chan, V. (2021). Correction of Bileaflet Mitral Valve Prolapse Through Reduction of Posterior Leaflet  Height. The Annals of Thoracic Surgery111(1), e55–e56. https://doi.org/10.1016/j.athoracsur.2020.04.131

Dhanani, S., Hornby, L., van Beinum, A., Scales, N. B., Hogue, M., Baker, A., Beed, S., Boyd, J. G., Chandler, J. A., Chassé, M., D’Aragon, F., Dezfulian, C., Doig, C. J., Duska, F., Friedrich, J. O., Gardiner, D., Gofton, T., Harvey, D., Herry, C., …So, D., … Shemie, S. D. (2021). Resumption of Cardiac Activity after Withdrawal of Life-Sustaining Measures. The New England Journal of Medicine384(4), 345–352. https://doi.org/10.1056/NEJMoa2022713

Edwards, J. D., Black, S. E., Boe, S., Boyd, L., Chaves, A., Chen, R., Dukelow, S., Fung, J., Kirton, A., Meltzer, J., Moussavi, Z., Neva, J., Paquette, C., Ploughman, M., Pooyania, S., Rajji, T. K., Roig, M., Tremblay, F., & Thiel, A. (2021). Canadian Platform for Trials in Noninvasive Brain Stimulation (CanStim) Consensus Recommendations for Repetitive Transcranial Magnetic Stimulation in Upper Extremity Motor Stroke Rehabilitation Trials. Neurorehabilitation and Neural Repair35(2), 103–116. https://doi.org/10.1177/1545968320981960

Fernando, S. M., Mathew, R., Slutsky, A. S., Rochwerg, B., Kyeremanteng, K., Combes, A., & Brodie, D. (2021). Media Portrayals of Outcomes After Extracorporeal Membrane Oxygenation. JAMA Internal Medicine. https://doi.org/10.1001/jamainternmed.2020.6094

Guo, M. H., Cole, E., Fei, L. Y. N., Mussani, J., Tran, D., Glineur, D., & Boodhwani, M. (2021). Preoperative left ventricular end-systolic dimension predicts occurrence of aortic insufficiency following aortic valve preservation and repair surgery. Journal of Thoracic and Cardiovascular Surgery. https://doi.org/10.1016/j.jtcvs.2020.10.159

Hoeper, M. M., Gomez Sanchez, M.-A., Humbert, M., Pittrow, D., Simonneau, G., Gall, H., Grünig, E., Klose, H., Halank, M., Langleben, D., Snijder, R. J., Escribano Subias, P., Mielniczuk, L. M., Lange, T. J., Vachiéry, J.-L., Wirtz, H., Helmersen, D. S., Tsangaris, I., Barberà, J. A., … Ghofrani, H.-A. (2021). Riociguat treatment in patients with pulmonary arterial hypertension: Final safety data from the EXPERT registry. Respiratory Medicine177. https://doi.org/10.1016/j.rmed.2020.106241

Jabagi, H., Juanda, N., Nantsios, A., & Boodhwani, M. (2021). Aortic arch surgery at 32°C: mild hypothermia and unilateral antegrade cerebral  perfusion. Interactive Cardiovascular and Thoracic Surgery. https://doi.org/10.1093/icvts/ivaa321

Juneau, D., Wu, K. Y., Kaps, N., Yao, J., Renaud, J. M., Beanlands, R. S. B., Ruddy, T. D., & deKemp, R. A. (2021). Internal validation of myocardial flow reserve PET imaging using stress/rest  myocardial activity ratios with Rb-82 and N-13-ammonia. Journal of Nuclear Cardiology : Official Publication of the American Society of  Nuclear Cardiology. https://doi.org/10.1007/s12350-020-02464-y

Kong, D., Munch, M., Qiqige, Q., Cooze, C. J. C., Rotstein, B. H., & Lundgren, R. J. (2021). Fast Carbon Isotope Exchange of Carboxylic Acids Enabled by Organic Photoredox  Catalysis. Journal of the American Chemical Society. https://doi.org/10.1021/jacs.0c12819

Kuk, M., Ward, N. C., & Dwivedi, G. (2021). Extrinsic and Intrinsic Responses in the Development and Progression of Atherosclerosis. Heart Lung and Circulation. https://doi.org/10.1016/j.hlc.2020.12.002

Lauten, A., Rudolph, T. K., Messika-Zeitoun, D., Thambyrajah, J., Serra, A., Schulz, E., Frey, N., Maly, J., Aiello, M., Lloyd, G., Bortone, A. S., Clerici, A., Delle-Karth, G., Rieber, J., Indolfi, C., Mancone, M., Belle, L., Arnold, M., Bouma, B. J., … Steeds, R. P. (2021). Management of patients with severe aortic stenosis in the TAVI-era: How recent recommendations are translated into clinical practice. Open Heart8(1). https://doi.org/10.1136/openhrt-2020-001485

Marbach, J. A., Wells, G., Santo, P. Di, So, D., Chong, A.-Y., Russo, J., Labinaz, M., Dick, A., Froeschl, M., Glover, C., Hibbert, B., Marquis, J.-F., MacDougall, A., Kass, M., Paddock, V., Quraishi, A. U. R., Chandrasekhar, J., Ghosh, N., Bernick, J., & Le May, M. (2021). Acute kidney injury after radial or femoral artery access in ST-segment elevation  myocardial infarction: AKI-SAFARI. American Heart Journal234, 12–22. https://doi.org/10.1016/j.ahj.2020.12.019

Mehri, R., Alatrash, A., Ogrodnik, N., Matida, E. A., & Fiorenza, F. (2021). In vitro investigation of the FlussoTM Bypass adapter efficiency upon ventilator circuit disconnect in a clinical simulated environment. Canadian Journal of Respiratory Therapy56, 86–91. https://doi.org/10.29390/CJRT-2020-033

Moghaddam, N., van Diepen, S., So, D., Lawler, P. R., & Fordyce, C. B. (2021). Cardiogenic shock teams and centres: a contemporary review of multidisciplinary care  for cardiogenic shock. ESC Heart Failure. https://doi.org/10.1002/ehf2.13180

Mullen, K. A., Walker, K. L., Hobler, L. A., Wells, G. A., Moroz, I. A., Pipe, A. L., Patzer, K., Aitken, D. A., & Reid, R. D. (2021). Performance Obligations to Improve Delivery of Hospital-Initiated Smoking Cessation  Interventions: A Before-and-After Evaluation. Nicotine & Tobacco Research : Official Journal of the Society for Research on  Nicotine and Tobacco23(1), 77–84. https://doi.org/10.1093/ntr/ntz186

Muñoz, M., Comtois-Bona, M., Cortes, D., Cimenci, C. E., Du, Q., Thompson, C., Figueroa, J. D., Franklin, V., Liu, P., & Alarcon, E. I. (2021). Integrated photothermal decontamination device for N95 respirators. Scientific Reports11(1). https://doi.org/10.1038/s41598-020-80908-8

Muser, D., Nucifora, G., Pieroni, M., Castro, S. A., Casado Arroyo, R., Maeda, S., Benhayon, D. A., Liuba, I., Sadek, M., Magnani, S., Enriquez, A., Liang, J. J., Sassone, B., Desjardins, B., Dixit, S., Deo, R., Garcia, F. C., Callans, D. J., Frankel, D. S., … Santangeli, P. (2021). Prognostic Value of Non-Ischemic Ring-Like Left Ventricular Scar in Patients with  Apparently Idiopathic Non-Sustained Ventricular Arrhythmias. Circulation. https://doi.org/10.1161/CIRCULATIONAHA.120.047640

Nair, V., Belanger, E. C., Lamacie, M. M., Davies, R. A., & Veinot, J. P. (2021). Unexpected diagnosis of metastatic breast carcinoma in an endomyocardial biopsy done for cardiac allograft rejection evaluation. Cardiovascular Pathology50, 107266. https://doi.org/10.1016/j.carpath.2020.107266

Nolan, R. P., Ross, H. J., Farkouh, M. E., Huszti, E., Chan, S., Toma, M., D’Antono, B., White, M., Thomas, S., Barr, S. I., Perreault, S., McDonald, M., Zieroth, S., Isaac, D., Wielgosz, A., & Mielniczuk, L. M. (2021). Automated E-Counseling for Chronic Heart Failure: CHF-CePPORT Trial. Circulation. Heart Failure14(1), e007073. https://doi.org/10.1161/CIRCHEARTFAILURE.120.007073

Oh, Y., Yang, S., Liu, X., Jana, S., Izaddoustdar, F., Gao, X., Debi, R., Kim, D.-K., Kim, K.-H., Yang, P., Kassiri, Z., Lakin, R., & Backx, P. H. (2020). Transcriptomic Bioinformatic Analyses of Atria Uncover Involvement of Pathways Related to Strain and Post-translational Modification of Collagen in Increased Atrial Fibrillation Vulnerability in Intensely Exercised Mice. Frontiers in Physiology11. https://doi.org/10.3389/fphys.2020.605671

Ouk, M., Wu, C.-Y., Rabin, J. S., Edwards, J. D., Ramirez, J., Masellis, M., Swartz, R. H., Herrmann, N., Lanctôt, K. L., Black, S. E., Swardfager, W., & Initiative, A. D. N. (2021). Associations between brain amyloid accumulation and the use of angiotensin-converting enzyme inhibitors versus angiotensin receptor blockers. Neurobiology of Aging100, 22–31. https://doi.org/10.1016/j.neurobiolaging.2020.12.011

Rahmouni, K., Hébert, Y., Pellerin, M., & Perrault, L. P. (2021). Sudden Tamponade due to Vein Graft Side Branch Avulsion Upon Removal of Temporary  Pacemaker Wires. In The Annals of thoracic surgery. https://doi.org/10.1016/j.athoracsur.2020.10.060

Robillard, R., Daros, A. R., Phillips, J. L., Porteous, M., Saad, M., Pennestri, M.-H., Kendzerska, T., Edwards, J. D., Solomonova, E., Bhatla, R., Godbout, R., Kaminsky, Z., Boafo, A., & Quilty, L. C. (2021). Emerging New Psychiatric Symptoms and the Worsening of Pre-existing Mental Disorders  during the COVID-19 Pandemic: A Canadian Multisite Study: Nouveaux symptômes psychiatriques émergents et détérioration des troubles mentaux préexistants pendanturant la pandémie de la COVID-19: une étude canadienne multisite. Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie, 706743720986786. https://doi.org/10.1177/0706743720986786

Sapp, J. A., Gillis, A. M., AbdelWahab, A., Nault, I., Nery, P. B., Healey, J. S., Raj, S. R., Lockwood, E., Sterns, L. D., Sears, S. F., Wells, G. A., Yee, R., Philippon, F., Tang, A., & Parkash, R. (2021). Remote-only monitoring for patients with cardiac implantable electronic devices: a  before-and-after pilot study. CMAJ Open9(1), E53–E61. https://doi.org/10.9778/cmajo.20200041

Steeds, R. P., Messika-Zeitoun, D., Thambyrajah, J., Serra, A., Schulz, E., Maly, J., Aiello, M., Rudolph, T. K., Lloyd, G., Bortone, A. S., Clerici, A., Delle-Karth, G., Rieber, J., Indolfi, C., Mancone, M., Belle, L., Lauten, A., Arnold, M., Bouma, B. J., … Frey, N. (2021). IMPULSE: The impact of gender on the presentation and management of aortic stenosis across Europe. Open Heart8(1). https://doi.org/10.1136/openhrt-2020-001443

Sun, L. Y., Rodger, J., Duffett, L., Tulloch, H., Crean, A. M., Chong, A.-Y., Rubens, F. D., MacPhee, E., Mesana, T. G., Lee, D. S., van Diepen, S., Beanlands, R. S., Ruel, M., Julien, A.-M., & Bilodeau, J. (2021). Derivation of Patient-Defined Adverse Cardiovascular and Noncardiovascular Events Through a Modified Delphi Process. JAMA Network Open4(1), e2032095. https://doi.org/10.1001/jamanetworkopen.2020.32095

Tulloch, H., Johnson, S., Demidenko, N., Clyde, M., Bouchard, K., & Greenman, P. S. (2020). An attachment-based intervention for patients with cardiovascular disease and their  partners: A proof-of-concept study. Health Psychology : Official Journal of the Division of Health Psychology, American  Psychological Association. https://doi.org/10.1037/hea0001034

Way, K. L., Vidal-Almela, S., Moholdt, T., Currie, K. D., Aksetøy, I.-L. A., Boidin, M., Cornelissen, V. A., Joa, K.-L., Keech, A., Jayo-Montoya, J. A., Taylor, J. L., Fouriner, K., & Reed, J. L. (2021). Sex Differences in Cardiometabolic Health Indicators following HIIT in Patients with  Coronary Artery Disease. Medicine and Science in Sports and Exercise. https://doi.org/10.1249/MSS.0000000000002596

Zelt, J. G. E., Schock, S., deKemp, R. A., Stewart, D. J., Staines, W. A., Ahmadi, A., Beanlands, R., & Mielniczuk, L. M. (2021). [(11)C]meta-hydroxyephedrine PET evaluation in experimental pulmonary arterial  hypertension: Effects of carvedilol of right ventricular sympathetic function. Journal of Nuclear Cardiology : Official Publication of the American Society of  Nuclear Cardiology. https://doi.org/10.1007/s12350-020-02494-6