Recent Publications


Ahmad, S., Shanmugasegaram, S., Walker, K. L., & Prince, S. A. (2017). Examining sedentary time as a risk factor for cardiometabolic diseases and their markers in South Asian adults: a systematic review. International Journal of Public Health.

Al-Atassi, T., Kimmaliardjuk, D.-M., Dagenais, C., Bourke, M., Lam, B.-K., & Rubens, F. D. (2017). Should We Ablate Atrial Fibrillation During Coronary Artery Bypass Grafting and Aortic Valve Replacement? The Annals of Thoracic Surgery.

Alenazy, A. B., Wells, R. G., & Ruddy, T. D. (2017). New solid state cadmium-zinc-telluride technology for cardiac single photon emission computed tomographic myocardial perfusion imaging. Expert Review of Medical Devices, 14(3), 213-222.

Alqahtani, A. M., Boczar, K. E., Kansal, V., Chan, K., Dwivedi, G., & Chow, B. J. W. (2017). Quantifying Aortic Valve Calcification using Coronary Computed Tomography Angiography. Journal of Cardiovascular Computed Tomography, 11(2), 99-104.

Capoulade, R., Chan, K. L., Mathieu, P., Bosse, Y., Dumesnil, J. G., Tam, J. W., Teo, K. K., Yang, X., Witztum, J. L., Arsenault, B. J., Despres, J.-P., Pibarot, P., & Tsimikas, S. (2017). Autoantibodies and immune complexes to oxidation-specific epitopes and progression of aortic stenosis: Results from the ASTRONOMER trial. Atherosclerosis, 260, 1-7.

Chan, V., Mesana, T., & Verma, S. (2017). Functional mitral stenosis following mitral valve repair. Current Opinion in Cardiology, 32(2), 161-165.

Clyde, M., Pipe, A., Els, C., Reid, R., & Tulloch, H. (2017). Factor structure of the Smoking Cessation Self-Efficacy Questionnaire among smokers with and without a psychiatric diagnosis. Psychology of Addictive Behaviors, 31(2), 162-170.

Gasbarrino, K., Zheng, H., Hafiane, A., Veinot, J. P., Lai, C., & Daskalopoulou, S. S. (2017). Decreased Adiponectin-Mediated Signaling Through the AdipoR2 Pathway Is Associated With Carotid Plaque Instability. Stroke, 48(4), 915-924.

Juneau, D., Erthal, F., Clarkin, O., Alzahrani, A., Alenazy, A., Hossain, A., Inacio, J. R., Dwivedi, G., Dick, A. J., Rybicki, F. J., & Chow, B. J. W. (2017). Mid-diastolic left ventricular volume and mass: Normal values for coronary computed tomography angiography. Journal of Cardiovascular Computed Tomography, 11(2), 135-140.

Khera, A. V, Won, H.-H., Peloso, G. M., O’Dushlaine, C., Liu, D., Stitziel, N. O., Natarajan, P., Nomura, A., Emdin, C. A., Gupta, N., Borecki, I. B., Asselta, R., Duga, S., Merlini, P. A., Correa, A., Kessler, T., Wilson, J. G., Bown, M. J., Hall, A. S., Braund, P. S., Carey, D. J., Murray, M. F., Kirchner, H. L., Leader, J. B., Lavage, D. R., Manus, J. N., Hartzel, D. N., Samani, N. J., Schunkert, H., Marrugat, J., Elosua, R., McPherson, R., Farrall, M., Watkins, H., Lander, E. S., Rader, D. J., Danesh, J., Ardissino, D., Gabriel, S., Willer, C., Abecasis, G. R., Saleheen, D., Dewey, F. E., & Kathiresan, S. (2017). Association of Rare and Common Variation in the Lipoprotein Lipase Gene With Coronary Artery Disease. JAMA, 317(9), 937-946.

Kimmaliardjuk, D. M., & Ruel, M. (2017). Cardiac passive-aggressive behavior? The right ventricle in patients with a left ventricular assist device. Expert Review of Cardiovascular Therapy, 1-10.

Laffont, B., & Rayner, K. J. (2017). MicroRNAs in the Pathobiology and Therapy of Atherosclerosis. The Canadian Journal of Cardiology, 33(3), 313-324.

Maeda, K., Alarcon, E. I., Suuronen, E. J., & Ruel, M. (2017). Optimizing the host substrate environment for cardiac angiogenesis, arteriogenesis, and myogenesis. Expert Opinion on Biological Therapy, 17(4), 435-447.

Mielniczuk, L. M., Toth, G. G., Xie, J. X., De Bruyne, B., Shaw, L. J., & Beanlands, R. S. (2017). Can Functional Testing for Ischemia and Viability Guide Revascularization? JACC. Cardiovascular Imaging, 10(3), 354-364.

Ohira, H., Mc Ardle, B., DeKemp, R. A., Nery, P. B., Juneau, D., Renaud, J. M., Klein, R., Clarkin, O., MacDonald, K., Leung, E., Nair, G., Beanlands, R. S. B., & Birnie, D. (2017). Inter- and Intra- observer agreement of FDG-PET/CT image interpretation in patients referred for assessment of Cardiac Sarcoidosis. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine.

Pupkaite, J., Ahumada, M., Mclaughlin, S., Temkit, M., Alaziz, S., Seymour, R., Ruel, M., Kochevar, I., Griffith, M., Suuronen, E. J., & Alarcon, E. I. (2017). Collagen-Based Photoactive Agent for Tissue Bonding. ACS Applied Materials & Interfaces, 9(11), 9265-9270.

Riddell, M. A., Edwards, N., Thompson, S. R., Bernabe-Ortiz, A., Praveen, D., Johnson, C., Kengne, A. P., Liu, P., McCready, T., Ng, E., Nieuwlaat, R., Ovbiagele, B., Owolabi, M., Peiris, D., Thrift, A. G., Tobe, S., & Yusoff, K. (2017). Developing consensus measures for global programs: lessons from the Global Alliance for Chronic Diseases Hypertension research program. Globalization and Health, 13(1), 17.

Rodriguez, M. L., Lapierre, H. R., Sohmer, B., Glineur, D., & Ruel, M. (2017). Mid-Term Follow-up of Minimally Invasive Multivessel Coronary Artery Bypass Grafting: Is the Early Learning Phase Detrimental? Innovations (Philadelphia, Pa.).

Sapp, J. L., Parkash, R., & Wells, G. (2017, March). Early Catheter Ablation for Unstable Ventricular Tachycardia: Still Too Early to Tell. Circulation. Arrhythmia and Electrophysiology. United States.

Sapp, J. L., Parkash, R., Wells, G. A., Yetisir, E., Gardner, M. J., Healey, J. S., Thibault, B., Sterns, L. D., Birnie, D., Nery, P. B., Sivakumaran, S., Essebag, V., Dorian, P., & Tang, A. S. L. (2017). Cardiac Resynchronization Therapy Reduces Ventricular Arrhythmias in Primary but Not Secondary Prophylactic Implantable Cardioverter Defibrillator Patients: Insight From the Resynchronization in Ambulatory Heart Failure Trial. Circulation. Arrhythmia and Electrophysiology, 10(3).

Singh, J. A., Hossain, A., Tanjong Ghogomu, E., Mudano, A. S., Maxwell, L. J., Buchbinder, R., Lopez-Olivo, M. A., Suarez-Almazor, M. E., Tugwell, P., & Wells, G. A. (2017). Biologics or tofacitinib for people with rheumatoid arthritis unsuccessfully treated with biologics: a systematic review and network meta-analysis. The Cochrane Database of Systematic Reviews, 3, CD012591.

Tissot-Dupont, H., Casalta, J. P., Gouriet, F., Hubert, S., Salaun, E., Habib, G., Fernandez-Gerlinger, M. P., Mainardi, J. L., Tattevin, P., Revest, M., Lucht, F., Botelho-Nevers, E., Gagneux-Brunon, A., Snygg-Martin, U., Chan, K. L., Bishara, J., Vilacosta, I., Olmos, C., San Roman, J. A., Lopez, J., Tornos, P., Fernandez-Hidalgo, N., Durante-Mangoni, E., Utili, R., Paul, M., Baddour, L. M., De Simone, D. C., Sohail, M. R., Steckelberg, J. M., Wilson, W. R., & Raoult, D. (2017). International experts’ practice in the antibiotic therapy of infective endocarditis is not following the guidelines. Clinical Microbiology and Infection : The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases.

Zakariyah, A. F., Rajgara, R. F., Veinot, J. P., Skerjanc, I. S., & Burgon, P. G. (2017). Congenital heart defect causing mutation in Nkx2.5 displays in vivo functional deficit. Journal of Molecular and Cellular Cardiology, 105, 89-98.


Dojeiji, L., Taylor, A., Boland, C., Brennan, C., & Penney, R. (2017). Retail food reform: How to effectively bridge what we say and what we do in our hospital settings. Healthcare Management Forum, 30(2), 101-106.

Essebag, V., Proietti, R., Birnie, D. H., Wang, J., Douketis, J., Coutu, B., Parkash, R., Lip, G. Y. H., Hohnloser, S. H., Moriarty, A., Oldgren, J., Connolly, S. J., Ezekowitz, M., & Healey, J. S. (2017). Short-term dabigatran interruption before cardiac rhythm device implantation: multi-centre experience from the RE-LY trial. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal  of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology.

Gabrani-Juma, H., Clarkin, O. J., Pourmoghaddas, A., Driscoll, B., Wells, R. G., Dekemp, R. A., & Klein, R. (2017). Validation of a Multimodality Flow Phantom and Its Application for Assessment of Dynamic SPECT and PET Technologies. IEEE Transactions on Medical Imaging, 36(1), 132-141.

Hamel, V., Cheng, K., Liao, S., Lu, A., Zheng, Y., Chen, Y., Xie, Y., & Liang, W. (2017). De Novo Human Cardiac Myocytes for Medical Research: Promises and Challenges. Stem Cells International, 2017, 4528941.

Le May, M. R., & Wells, G. A. (2017, February). Unraveling the Radial Paradox. Circulation. Cardiovascular Interventions. United States.

Maeda, K., Seymour, R., Ruel, M., & Suuronen, E. J. (2017). Echocardiography-Guided Intramyocardial Injection Method in a Murine Model. Methods in Molecular Biology (Clifton, N.J.), 1553, 217-225.

Ocneanu, A. F., deKemp, R. A., Renaud, J. M., Adler, A., Beanlands, R. S. B., & Klein, R. (2017). Optimally Repeatable Kinetic Model Variant for Myocardial Blood Flow Measurements with 82Rb PET. Computational and Mathematical Methods in Medicine, 2017, 6810626.

Padfield, G. J., Steinberg, C., Swampillai, J., Qian, H., Connolly, S. J., Dorian, P., Green, M. S., Humphries, K. H., Klein, G. J., Sheldon, R., Talajic, M., & Kerr, C. R. (2017). Progression of paroxysmal to persistent atrial fibrillation: Canadian Registry of Atrial Fibrillation 10-year follow-up. Heart Rhythm.

Parkash, R., Wells, G. A., Sapp, J. L., Healey, J. S., Tardif, J.-C., Greiss, I., Rivard, L., Roux, J.-F., Gula, L., Nault, I., Novak, P. G., Birnie, D. H., Ha, A. C., Wilton, S. B., Mangat, I., Gray, C. J., Gardner, M. J., & Tang, A. S. L. (2017). The Effect of Aggressive Blood Pressure Control on the Recurrence of Atrial Fibrillation After Catheter Ablation: A Randomized, Open Label, Clinical Trial (Substrate Modification with Aggressive Blood Pressure Control: SMAC- AF). Circulation.

Pourdjabbar, A., Hibbert, B., Chong, A.-Y., Le May, M. R., Labinaz, M., Simard, T., Daniel Ramirez, F., Lugomirski, P., Maze, R., Froeschl, M., Glove, C., Dick, A., Marquis, J.-F., Bernick, J., Wells, G., & So, D. Y. F. (2017). A randomised study for optimising crossover from ticagrelor to clopidogrel in patients with acute coronary syndrome. Thrombosis and Haemostasis, 117(2), 303-310.

Reed, J. L., Prince, S. A., Elliott, C. G., Mullen, K.-A. K.-A., Tulloch, H. E., Hiremath, S., Cotie, L. M., Pipe, A. L., & Reid, R. D. (2017). Impact of workplace physical activity interventions on physical activity and cardiometabolic health among working-age women. Circulation: Cardiovascular Quality and Outcomes, 10(2).

Simard, T., Jung, R. G., Motazedian, P., Di Santo, P., Ramirez, F. D., Russo, J. J., Labinaz, A., Yousef, A., Anantharam, B., Pourdjabbar, A., & Hibbert, B. (2017). Progenitor Cells for Arterial Repair: Incremental Advancements towards Therapeutic Reality. Stem Cells International, 2017, 8270498.

Webb, T. R., Erdmann, J., Stirrups, K. E., Stitziel, N. O., Masca, N. G. D., Jansen, H., Kanoni, S., Nelson, C. P., Ferrario, P. G., Konig, I. R., Eicher, J. D., Johnson, A. D., Hamby, S. E., Betsholtz, C., Ruusalepp, A., Franzen, O., Schadt, E. E., Bjorkegren, J. L. M., Weeke, P. E., Auer, P. L., . Kathiresan, S. (2017). Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease. Journal of the American College of Cardiology, 69(7), 823-836.


Aleksova, N., Juneau, D., Dick, A., Green, M., Birnie, D., Beanlands, R. S., & Nery, P. B. (2017). Role of 18F-Fluorodeoxyglucose/Positron Emission Tomography Imaging to Demonstrate Resolution of Acute Myocarditis. The Canadian Journal of Cardiology, 33(2), 293.e3-293.e5.

Andreini, D., Pontone, G., Mushtaq, S., Gransar, H., Conte, E., Bartorelli, A. L., Pepi, M., Opolski, M. P., O Hartaigh, B., Berman, D. S., Budoff, M. J., Achenbach, S., Al-Mallah, M., Cademartiri, F., Callister, T. Q., Chang, H.-J., Chinnaiyan, K., Chow, B. J. W., Cury, R., Delago, A., Hadamitzky, M., Hausleiter, J., Feuchtner, G., Kim, Y.-J., Kaufmann, P. A., Leipsic, J., Lin, F. Y., Maffei, E., Raff, G., Shaw, L. J., Villines, T. C., Dunning, A., Marques, H., Rubinshtein, R., Hindoyan, N., Gomez, M., & Min, J. K. (2017). Long-term prognostic impact of CT-Leaman score in patients with non-obstructive CAD: Results from the COronary CT Angiography EvaluatioN For Clinical Outcomes InteRnational Multicenter (CONFIRM) study. International Journal of Cardiology, 231, 18-25.

Bennett, M., Parkash, R., Nery, P., Senechal, M., Mondesert, B., Birnie, D., Sterns, L. D., Rinne, C., Exner, D., Philippon, F., Campbell, D., Cox, J., Dorian, P., Essebag, V., Krahn, A., Manlucu, J., Molin, F., Slawnych, M., & Talajic, M. (2017). Canadian Cardiovascular Society/Canadian Heart Rhythm Society 2016 Implantable Cardioverter-Defibrillator Guidelines. The Canadian Journal of Cardiology, 33(2), 174-188.

Cheung, K., Boodhwani, M., Chan, K.-L., Beauchesne, L., Dick, A., & Coutinho, T. (2017). Thoracic Aortic Aneurysm Growth: Role of Sex and Aneurysm Etiology. Journal of the American Heart Association, 6(2).

Clarke, B., Ducharme, A., Giannetti, N., Kim, D., McDonald, M., Pflugfelder, P., Rajda, M., Senechal, M., Stadnick, E., Toma, M., Zieroth, S., & Isaac, D. (2017). Multicenter evaluation of a national organ sharing policy for highly sensitized patients listed for heart transplantation in Canada. The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation.

Clavel, M.-A., Burwash, I. G., & Pibarot, P. (2017). Cardiac Imaging for Assessing Low-Gradient Severe Aortic Stenosis. JACC. Cardiovascular Imaging, 10(2), 185-202.

Czarnecki, A., Qiu, F., Koh, M., Prasad, T. J., Cantor, W. J., Cheema, A. N., W A Chu, M., Feindel, C., Fremes, S. E., Kingsbury, K., Natarajan, M. K., Peterson, M. D., Ruel, M., Strauss, B. H., Wijeysundera, H. C., & Ko, D. T. (2017). Clinical outcomes after trans-catheter aortic valve replacement in men and women  in Ontario, Canada. Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions.

de Bold, A. J., & de Bold, M. L. (2017). Techniques for the Evaluation of the Genetic Expression, Intracellular Storage, and Secretion of Polypeptide Hormones with Special Reference to the Natriuretic Peptides (NPs). Methods in Molecular Biology (Clifton, N.J.), 1527, 163-176.

Fleischmann, R., Tongbram, V., van Vollenhoven, R., Tang, D. H., Chung, J., Collier, D., Urs, S., Ndirangu, K., Wells, G., & Pope, J. (2017). Systematic review and network meta-analysis of the efficacy and safety of tumour  necrosis factor inhibitor-methotrexate combination therapy versus triple therapy in rheumatoid arthritis. RMD Open, 3(1), e000371.

Gaudino, M., Puskas, J. D., Di Franco, A., Ohmes, L. B., Iannaccone, M., Barbero, U., Glineur, D., Grau, J. B., Benedetto, U., D’Ascenzo, F., Gaita, F., Girardi, L. N., & Taggart, D. P. (2017). Three Arterial Grafts Improve Late Survival: A Meta-Analysis of Propensity Matched Studies. Circulation.

Hage, A., Hage, F., Toeg, H., Davies, R., & Boodhwani, M. (2017). Aortic dissection following heart transplantation. Journal of Cardiac Surgery, 32(2), 156-158.

Kavurma, M. M., Rayner, K. J., & Karunakaran, D. (2017). The walking dead: macrophage inflammation and death in atherosclerosis. Current Opinion in Lipidology.

Kimmaliardjuk, D. M., Chan, V., & Ruel, M. (2017). Invited Commentary. The Annals of Thoracic Surgery, 103(2), 593-594.

Kipp, R. T., Abu Sham’a, R., Hiroyuki, I., Han, F. T., Refaat, M., Hsu, J. C., Field, M. E., Kopp, D. E., Marcus, G. M., Scheinman, M. M., & Hoffmayer, K. S. (2017). Concealed Accessory Pathways with a Single Ventricular and Two Discrete Atrial Insertion Sites. Pacing and Clinical Electrophysiology : PACE.

Linseman, T., Soubeyrand, S., Martinuk, A., Nikpay, M., Lau, P., & McPherson, R. (2017). Functional Validation of a Common Nonsynonymous Coding Variant in ZC3HC1 Associated With Protection From Coronary Artery Disease. Circulation. Cardiovascular Genetics, 10(1).

Major, J. L., Dewan, A., Salih, M., Leddy, J. J., & Tuana, B. S. (2017). E2F6 Impairs Glycolysis and Activates BDH1 Expression Prior to Dilated Cardiomyopathy. PloS One, 12(1), e0170066.

Nikpay, M., Stewart, A. F. R., & McPherson, R. (2017). Partitioning the heritability of Coronary Artery Disease highlights the importance of immune-mediated processes and epigenetic sites associated with transcriptional activity. Cardiovascular Research.

Ramirez, F. D., Motazedian, P., Jung, R. G., Di Santo, P., MacDonald, Z., Simard, T., Clancy, A. A., Russo, J. J., Welch, V., Wells, G. A., & Hibbert, B. (2017). Sex Bias Is Increasingly Prevalent in Preclinical Cardiovascular Research: Implications for Translational Medicine and Health Equity for Women: A Systematic Assessment of Leading Cardiovascular Journals Over a 10-Year Period. Circulation. United States.

Rayner, K. J. (2017). A big shot of small RNAs repairs a broken heart. Science Translational Medicine, 9(374).

Renaud, J. M., Moody, J. B., & deKemp, R. A. (2017). Reply: Variation in maximum count rates during myocardial blood flow quantification using Rubidium-82 PET. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine.

Rodriguez, M. L., Glineur, D., & Ruel, M. (2017). Consideration of Native Coronary Disease Progression in the Decision to Perform Hybrid Coronary Revascularization. Innovations (Philadelphia, Pa.), 12(1), 1-3.

Russo, J. J., James, T. E., Hibbert, B., Yousef, A., Osborne, C., Wells, G. A., Froeschl, M. P. V, So, D. Y., Chong, A. Y., Labinaz, M., Glover, C. A., Marquis, J.-F., Dick, A., Bernick, J., & Le May, M. R. (2017). Impact of mean arterial pressure on clinical outcomes in comatose survivors of out-of-hospital cardiac arrest: Insights from the University of Ottawa Heart Institute Regional Cardiac Arrest Registry (CAPITAL-CARe). Resuscitation, 113, 27-32.

Saw, J., Fahmy, P., Azzalini, L., Marquis, J.-F., Hibbert, B., Morillo, C., Carrizo, A., & Ibrahim, R. (2017). Early Canadian Multi-Center Experience with WATCHMAN for Percutaneous Left Atrial Appendage Closure. Journal of Cardiovascular Electrophysiology.

Stiell, I. G., Clement, C. M., Rowe, B. H., Brison, R. J., Wyse, D. G., Birnie, D., Dorian, P., Lang, E., Perry, J. J., Borgundvaag, B., Eagles, D., Redfearn, D., Brinkhurst, J., & Wells, G. A. (2017). Outcomes for Emergency Department Patients With Recent-Onset Atrial Fibrillation  and Flutter Treated in Canadian Hospitals. Annals of Emergency Medicine.

Wijeysundera, H. C., Qiu, F., Koh, M., Prasad, T. J., Cantor, W. J., Cheema, A., Chu, M. W. A., Czarnecki, A., Feindel, C., Fremes, S. E., Kingsbury, K. J., Natarajan, M. K., Peterson, M., Ruel, M., Strauss, B., & Ko, D. T. (2017). Comparison of Outcomes of Balloon-Expandable Versus Self-Expandable Transcatheter Heart Valves for Severe Aortic Stenosis. The American Journal of Cardiology.