About Our Research

ORACLE

At the University of Ottawa Heart Institute (UOHI), research is closely integrated with clinical care. Affiliated with the University of Ottawa, we align research with clinical needs to establish a seamless linkage, effectively translating research from “bench to bedside.” Indeed, we are uniquely placed to achieve complete integration and synergy between clinical care and research innovation and excellence through our large patient population base.

Our investigators regularly publish in prestigious journals and our extensive network of partnerships encompass regional, national, and international activities. Since 2011, the Institute has been ranked in the top 3% of worldwide research institutions for normalized research impact, by Scimago Institutional Rankings (SIR), the most comprehensive ranking in this area. In 2014, we placed as the number one cardiovascular research centre in Canada. 

ORACLE

The Ottawa region’s cardiovascular disease research roadmap, the 2013-2017 Ottawa Region for Advanced Cardiovascular Research Excellence (ORACLE) Strategic Plan (pdf) builds on the UOHI’s clinical and research excellence, and leverages the diverse pool of expertise of our regional partners. The vision, under the leadership of Chief Scientific Officer Peter Liu, MD, is to position the Institute and regional partners in five years as key Canadian leaders in cardiovascular innovation and knowledge translation, and in 10 years to be recognized as among the top international hubs in cutting-edge cardiovascular research and knowledge implementation. To achieve this, we have created Innovation Clusters to foster collaboration, leverage Ottawa’s unique regional advantage, and generate lateral connectivity to harness talent, expertise, resources and opportunities. In turn, Ottawa is defining the next cutting edge and becoming a magnet for the global talent of trainees, rising research stars, and established investigators. For more information on ORACLE and ORACLE 1.5, see Research Priorities.

Research Infrastructure

The UOHI’s research infrastructure includes advanced equipment, endowed fellowships and research chairs, and data analysis and administrative support offices, all of which foster the pursuit of excellence, scientific achievement and clinical impact. Our research endeavours are supported through competitive funding obtained via grants and contracts, as well as a vigorous fundraising campaign by the Heart Institute Foundation (which includes a more than $50 million research endowment).

Our researchers are highly successful in obtaining competitive peer-reviewed grants awarded from the Canadian Institutes of Health Research, Heart and Stroke Foundation of Canada, Genome Canada, and the Ontario Ministry of Research and Innovation, among others. State-of-the-art research facilities at UOHI include the Ruddy Canadian Cardiovascular Genetics Centre (the only one of its kind in Canada), advanced cardiac imaging and analysis capabilities, electron microscopy, and a cyclotron facility. In addition, the Ottawa region is home to world class centres such as the Canadian Vascular Network, Heart Foundation Centre for Stroke Recovery, the Brain and Mind Research Institute, the Stem Cell Network, and the Canadian Stroke Network. Other core facility service laboratories, such as those provided by the University of Ottawa Faculty of Medicine, are available in the Ottawa region.

Education

In close collaboration with the University of Ottawa and Carleton University, the Heart Institute educates and trains undergraduates, graduates and post-graduates in an environment that mandates a vigorous pursuit of research.

Selected Research Publications

Our research has received worldwide recognition through publications in prestigious journals:

*Led by our Ottawa regional partners

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