Clinical Trials

Today’s research is tomorrow’s treatment! This is particularly true here at the University of Ottawa Heart Institute, where research spans from the laboratory to the patient’s bedside and back.

At any given time, the Heart Institute may have up to 200 active clinical trials, in various stages of the lifecycle of a study. Some projects are conducted only here at the Institute, while others are large national or international projects; some are led by us and others we participate in as a site. Thousands of patients and, in some cases, healthy volunteers, participate in our studies annually. Currently, we have 50 Scientists and Clinician Investigators leading research trials on site.

For more information please contact JoinAStudy@ottawaheart.ca.

Current Clinical Trials at the Heart Institute

Status Study
Recruiting RAdiolabeled Perfusion to Identify Coronary Artery Disease Using WAter To Evaluate Responses of Myocardial FLOW (RAPID-WATER-FLOW)
  • Conditions:Coronary Artery Disease
  • Sponsor:MedTrace Pharma A/S
Recruiting Blinded Randomized Trial of Anticoagulation to Prevent Ischemic Stroke and Neurocognitive Impairment in AF
  • Conditions:ATRIAL FIBRILLATION
  • Sponsor:Montreal Heart Institute, Canadian Stroke Prevention Intervention Network, The Montreal Health Innovations Coordinating Center (MHICC), Bayer Healthcare Pharmaceuticals, Inc./Bayer Schering Pharma, Montreal Heart Institute Foundation, Canadian Institutes of Health Research (CIHR), Hewitt Foundation
Recruiting A Study Comparing Abelacimab to Dalteparin in the Treatment of Gastrointestinal/Genitourinary Cancer and Associated VTE
  • Conditions:Venous Thromboembolism, Deep Venous Thrombosis, Pulmonary Embolism
  • Sponsor:Anthos Therapeutics, Inc., Itreas
Recruiting Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
  • Conditions:Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia, Mixed Phenotype Acute Leukemia, T Acute Lymphoblastic Leukemia
  • Sponsor:Children's Oncology Group, EsPhALL Network/ BFM Study Group, National Cancer Institute (NCI)
Recruiting The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study
  • Conditions:Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Acute Myeloid Leukemia Post Cytotoxic Therapy, Juvenile Myelomonocytic Leukemia, Mixed Phenotype Acute Leukemia, Myelodysplastic Syndrome, Myelodysplastic Syndrome Post Cytotoxic Therapy, Myeloid Leukemia Associated With Down Syndrome
  • Sponsor:LLS PedAL Initiative, LLC, Children's Oncology Group, National Cancer Institute (NCI)
Recruiting A Study to Test Asundexian to Prevent a Clot-related Stroke in Participants After an Acute Ischemic Stroke or High-risk TIA/Mini-stroke (Transient Ischemic Attack)
  • Conditions:Prevention of Ischemic Stroke, Acute Non-cardioembolic Ischemic Stroke, High-risk Transient Ischemic Attack
  • Sponsor:Bayer
Recruiting Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
  • Conditions:B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma, Central Nervous System Leukemia, Mixed Phenotype Acute Leukemia, Testicular Leukemia
  • Sponsor:Children's Oncology Group, National Cancer Institute (NCI)
Recruiting Stopping Tyrosine Kinase Inhibitors in Affecting Treatment-Free Remission in Patients With Chronic Phase Chronic Myeloid Leukemia
  • Conditions:Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive
  • Sponsor:Children's Oncology Group, National Cancer Institute (NCI)
Recruiting A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations
  • Conditions:Acute Myeloid Leukemia
  • Sponsor:Children's Oncology Group, National Cancer Institute (NCI)
Recruiting Project: Every Child for Younger Patients With Cancer
  • Conditions:Carcinoma In Situ, Central Nervous System Neoplasm, Childhood Immature Teratoma, Childhood Langerhans Cell Histiocytosis, Childhood Mature Teratoma, Congenital Mesoblastic Nephroma, Desmoid Fibromatosis, Lymphoproliferative Disorder, Malignant Solid Neoplasm, Myeloproliferative Neoplasm, Stromal Neoplasm
  • Sponsor:Children's Oncology Group, National Cancer Institute (NCI)
Recruiting A Study to Compare Early Use of Vinorelbine and Maintenance Therapy for Patients With High Risk Rhabdomyosarcoma
  • Conditions:Alveolar Rhabdomyosarcoma, Botryoid-Type Embryonal Rhabdomyosarcoma, Embryonal Rhabdomyosarcoma, Metastatic Embryonal Rhabdomyosarcoma, Metastatic Rhabdomyosarcoma, Solid Alveolar Rhabdomyosarcoma, Spindle Cell Rhabdomyosarcoma, Spindle Cell/Sclerosing Rhabdomyosarcoma
  • Sponsor:Children's Oncology Group, National Cancer Institute (NCI)
Recruiting A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT
  • Conditions:Anaplastic Kidney Wilms Tumor, Recurrent Kidney Wilms Tumor, Stage II Kidney Wilms Tumor, Stage III Kidney Wilms Tumor, Stage IV Kidney Wilms Tumor
  • Sponsor:Children's Oncology Group, National Cancer Institute (NCI)
Recruiting Web-Based Physical Activity Intervention in Improving Long Term Health in Children and Adolescents With Cancer
  • Conditions:Carcinoma In Situ, Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm
  • Sponsor:Children's Oncology Group, National Cancer Institute (NCI)
Recruiting Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
  • Conditions:Childhood Extracranial Germ Cell Tumor, Extragonadal Embryonal Carcinoma, Germ Cell Tumor, Malignant Germ Cell Tumor, Malignant Ovarian Teratoma, Stage I Ovarian Choriocarcinoma, Stage I Ovarian Embryonal Carcinoma AJCC v6 and v7, Stage I Ovarian Teratoma AJCC v6 and v7, Stage I Ovarian Yolk Sac Tumor AJCC v6 and v7, Stage I Testicular Choriocarcinoma AJCC v6 and v7, Stage I Testicular Embryonal Carcinoma AJCC v6 and v7, Stage I Testicular Seminoma AJCC v6 and v7, Stage I Testicular Yolk Sac Tumor AJCC v6 and v7, Stage II Ovarian Choriocarcinoma, Stage II Ovarian Embryonal Carcinoma AJCC v6 and v7, Stage II Ovarian Yolk Sac Tumor AJCC v6 and v7, Stage II Testicular Choriocarcinoma AJCC v6 and v7, Stage II Testicular Embryonal Carcinoma AJCC v6 and v7, Stage II Testicular Yolk Sac Tumor AJCC v6 and v7, Stage III Ovarian Choriocarcinoma, Stage III Ovarian Embryonal Carcinoma AJCC v6 and v7, Stage III Ovarian Yolk Sac Tumor AJCC v6 and v7, Stage III Testicular Choriocarcinoma AJCC v6 and v7, Stage III Testicular Embryonal Carcinoma AJCC v6 and v7, Stage III Testicular Yolk Sac Tumor AJCC v6 and v7, Stage IV Ovarian Choriocarcinoma, Stage IV Ovarian Embryonal Carcinoma AJCC v6 and v7, Stage IV Ovarian Yolk Sac Tumor AJCC v6 and v7, Testicular Mixed Choriocarcinoma and Embryonal Carcinoma, Testicular Mixed Choriocarcinoma and Teratoma, Testicular Mixed Choriocarcinoma and Yolk Sac Tumor
  • Sponsor:Children's Oncology Group, National Cancer Institute (NCI)
Recruiting Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma
  • Conditions:Medulloblastoma
  • Sponsor:Children's Oncology Group, National Cancer Institute (NCI)
Recruiting A Study of Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy
  • Conditions:Cardiomyopathy, Hypertrophic
  • Sponsor:Bristol-Myers Squibb
Recruiting Florbetaben for Imaging of Vascular Amyloid
  • Conditions:Acute Coronary Syndrome, Stroke, Transient Ischemic Attack, Atherosclerosis of Artery
  • Sponsor:Ottawa Heart Institute Research Corporation
Recruiting A Study to Assess Long-term Safety, Tolerability, and Efficacy of Rocatinlimab in Adult and Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)
  • Conditions:Atopic Dermatitis
  • Sponsor:Amgen
Recruiting A Study to Assess the Safety, Tolerability, and Efficacy of Rocatinlimab in Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)
  • Conditions:Atopic Dermatitis
  • Sponsor:Amgen
Recruiting Study of Sacituzumab Govitecan-hziy Versus Treatment of Physician's Choice in Patients With Previously Untreated Metastatic Triple-Negative Breast Cancer
  • Conditions:Triple Negative Breast Cancer, PD-L1 Negative
  • Sponsor:Gilead Sciences
Recruiting A Study Comparing Abelacimab to Apixaban in the Treatment of Cancer-associated VTE
  • Conditions:Venous Thromboembolism, Deep Venous Thrombosis, Pulmonary Embolism
  • Sponsor:Anthos Therapeutics, Inc., Itreas
Recruiting Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study
  • Conditions:Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
  • Sponsor:National Cancer Institute (NCI)
Recruiting Nivolumab in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed Primary Mediastinal B-Cell Lymphoma
  • Conditions:Primary Mediastinal Large B-Cell Lymphoma
  • Sponsor:National Cancer Institute (NCI)
Recruiting Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial
  • Conditions:Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease
  • Sponsor:Edwards Lifesciences
Recruiting MRI Assessment of Pulmonary Edema in Acute Heart Failure
  • Conditions:Acute Heart Failure, Pulmonary Edema With Heart Failure
  • Sponsor:University of Alberta, Canadian Institutes of Health Research (CIHR)
Recruiting A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia
  • Conditions:B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma, Down Syndrome
  • Sponsor:National Cancer Institute (NCI)
Recruiting Blood Flow Reserve: Effects After Training With Heavy Inspiratory Exercises
Recruiting Nicotinamide Chemoprevention for Keratinocyte Carcinoma in Solid Organ Transplant Recipients - Pivotal Trial
  • Conditions: Non-melanoma Skin Cancer,   Carcinoma, Squamous Cell,   Carcinoma, Basal Cell,   Keratinocyte Carcinoma
  • Sponsor: Women's College Hospital,   Canadian Institutes of Health Research (CIHR),   University Health Network, Toronto,   NOW Foods
Recruiting Reexamining Her Cardiovascular Risk - Ottawa WomeN's Longitudinal Cohort Study
  • Interventions: Diagnostic Test PET scan
Recruiting Active-control Randomised Trial Comparing 4-factor Prothrombin Complex Concentrate With Frozen Plasma in Cardiac Surgery
Recruiting COmparison of Bleeding Risk Between Rivaroxaban and Apixaban in Patients With Atrial Fibrillation
  • Sponsor: Ottawa Hospital Research Institute,   Canadian Venous Thromboembolism Clinical Trials and Outcomes Research (CanVECTOR) Network,   Canadian Institutes of Health Research (CIHR)
Recruiting Catheter Ablation Versus Radio-Ablation for Ventricular Tachycardia: a Randomized Controlled Trial
Recruiting Albumin To Enhance Recovery After Acute Kidney Injury
  • Conditions:Acute Kidney Injury, Renal Replacement Therapy, Hypotension, Critical Illness
  • Sponsor:Ottawa Hospital Research Institute, The Physicians' Services Incorporated Foundation, The Kidney Foundation of Canada, The Ottawa Hospital Academic Medical Organization (TOHAMO) Innovation Fund Grant.
Recruiting Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women
  • Conditions: Heart Diseases,   Coronary Artery Disease,   Coronary Artery Bypass Grafting
  • Sponsor: Weill Medical College of Cornell University,   New York Presbyterian Hospital,   Sunnybrook Health Sciences Centre,   Cedars-Sinai Medical Center,   Columbia University,   Duke University
Recruiting Effect of Colchicine on the Progression of Aortic Valve Stenosis - A Pilot Study
  • Conditions: Aortic Stenosis,   Inflammation
Recruiting CardiAMP™ Cell Therapy for Heart Failure Trial
Recruiting Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion
  • Conditions:Stroke, Patent Foramen Ovale
  • Sponsor:Occlutech International AB
Recruiting Evaluating the Use of a Remote Telehome Monitoring Hypertension Program for Patients Receiving Virtual Care
  • Interventions: Behavioral Telehome Monitoring
Recruiting Feasibility of High-Intensity Interval Nordic Walking in Patients With Coronary Artery Disease
Recruiting Patient Engagement Study to Evaluate the Use of Biological Therapies for Cardiac Arrhythmias
Recruiting Transcatheter Mitral Valve Repair for Inotrope Dependent Cardiogenic Shock
  • Conditions:Cardiogenic Shock, Mitral Regurgitation
  • Sponsor:Ottawa Heart Institute Research Corporation
Recruiting CAPITAL DOREMI 2: Inotrope Versus Placebo Therapy for Cardiogenic Shock
Recruiting An Evaluation of the Talk Test for Exercise Prescription for Home-Based Cardiac Rehabilitation
Recruiting AERIAL Trial: Antiplatelet Therapy in Heart Transplantation
  • Conditions: Cardiac Allograft Vasculopathy,   Heart Transplant
  • Sponsor: Ottawa Heart Institute Research Corporation,   Canadian Institutes of Health Research (CIHR)
Recruiting QOL Improvement After Cardioversion of Persistent AF (QOL-CAFRCT)
Recruiting Randomized Ablation-based AF Rhythm-control Versus Rate-control in Patients With HF and High-burden AF Extend
  • Conditions: Atrial Fibrillation,   Heart Failure
  • Interventions: 
Recruiting Acute Responses to Exercise in Females and Males With Symptomatic Atrial Fibrillation
  • Conditions: Atrial Fibrillation,   Persistent Atrial Fibrillation,   Paroxysmal Atrial Fibrillation
Recruiting Improving Goal Directed Medical Therapy for Device Clinic Patients With Reduced EF at UOHI: a QI Initiative (VIGILANT)
  • Interventions: 
  • Sponsor: Ottawa Heart Institute Research Corporation,   Novartis,   Servier,   AstraZeneca
Recruiting COVID-19 Vaccine-induced Inflammatory Heart Disease Prevalence Registry
  • Conditions: Myocarditis,   Pericarditis
  • Interventions: 
Recruiting A Randomized Trial of Lenient Versus Strict Arm Instruction Post Cardiac Device Surgery
Recruiting REvascularization and Valve Intervention for Ischemic Valve diseasE: REVIVE Trial
  • Conditions: Mitral Valve Insufficiency,   Coronary Artery Disease
Recruiting Watchman for Patients With Atrial Fibrillation Undergoing Transcatheter Mitral Valve Repair (WATCH-TMVR)
  • Conditions: Nonvalvular Atrial Fibrillation,   Severe Degenerative Mitral Regurgitation
  • Interventions: Procedure MitraClip TMVR and Watchman LAAO
Recruiting Bentracimab (PB2452) in Ticagrelor-treated Patients With Uncontrolled Major or Life-Threatening Bleeding or Requiring Urgent Surgery or Invasive Procedure
  • Conditions: Hemorrhage,   Urgent Surgery,   Invasive Procedure
  • Interventions: Drug Bentracimab (PB2452) Infusion
Recruiting Exercise Training in Women With Heart Disease
  • Conditions: Cardiovascular Diseases,   Coronary Heart Disease
  • Interventions: Behavioral Exercise
Recruiting Amplatzer Amulet LAAO vs. NOAC
  • Conditions: Atrial Fibrillation,   Stroke,   Bleeding
Recruiting MitraClip REPAIR MR Study
Recruiting Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation
  • Conditions: Mitral Regurgitation,   Mitral Insufficiency,   Mitral Valve Insufficiency,   Cardiovascular Diseases,   Valve Disease, Heart,   Heart Valve Diseases,   Functional Mitral Regurgitation,   Degenerative Mitral Valve Disease
Recruiting The Psychological, Social, and Economic Impacts of COVID-19
  • Conditions: COVID-19,   Chronic Disease,   Psychiatric Disorder,   Cardiovascular Diseases
  • Interventions: 
  • Sponsor: University of Ottawa,   Hopital du Sacre-Coeur de Montreal,   Sunnybrook Health Sciences Centre,   Southlake Regional Health Centre,   The Ottawa Hospital Research Institute,   Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal,   Centre for Addiction and Mental Health,   CHEO Research Institute,   Ottawa Heart Institute Research Corporation,   McGill University,   Johns Hopkins University,   Université de Montréal,   The Royal's Institute of Mental Health Research
Recruiting Exploratory Study of the Edwards Transcatheter Atrial Shunt System (ALt FLOW CANADA)
  • Interventions: Device Atrial Shunt
Recruiting Cytisine Compared to Combination NRT in Relapsed Smokers
  • Conditions: Smoking Cessation,   Coronary Artery Disease
Recruiting Canadian Study of Arterial Inflammation in Patients With Diabetes and Vascular Events: EvaluatioN of Colchicine
  • Conditions: Cardiovascular Diseases,   Atherosclerosis,   Inflammation,   Diabetes
  • Sponsor: Ottawa Heart Institute Research Corporation,   Canadian Institutes of Health Research (CIHR)
Recruiting Effect of a Hybrid Rehabilitation Program on Walking, Quality of Life & Cardiovascular Risk in People With PAD
  • Interventions: Behavioral HY-PAD
  • Sponsor: Ottawa Heart Institute Research Corporation,   AFP Innovation Fund
Recruiting Left Atrial Imaging Prior to Cardioversion: Leveraging Computed Tomography to Rule Out Thrombus
Recruiting Healing Hearts Together: Evaluating a Couples-based Intervention to Improve Health Outcomes
  • Interventions: Other Healing Hearts Together
Recruiting The Effect of High-Intensity Interval Training on Glucose Variability and Atrial Fibrillation Symptoms
  • Conditions: Atrial Fibrillation,   Type 2 Diabetes
  • Interventions: Behavioral High-intensity interval training + standard care
Recruiting The INITIATE Study: Initiating Nicotine Dependence Treatment for Smokers Admitted to Emergency Departments
  • Conditions: Nicotine Dependence, Cigarettes,   Nicotine Withdrawal
  • Interventions: Behavioral Quit Card Intervention (QCI)
  • Sponsor: Ottawa Heart Institute Research Corporation,   Canadian Institutes of Health Research (CIHR)
Recruiting Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance
  • Conditions: Ascending Aortic Aneurysm Enlargement,   Ascending Aorta Aneurysm
  • Interventions: Procedure Thoracic Aortic Surgery
  • Sponsor: Ottawa Heart Institute Research Corporation,   University of Calgary
Recruiting Multi-Center Evaluation of Feasibility of SPECT Measurement of Myocardial Blood Flow and Reserve
  • Interventions: 
  • Sponsor: Ottawa Heart Institute Research Corporation,   GE Healthcare
Recruiting Sildenafil for the Prevention of Right Heart Failure Following LVAD Implantation
  • Interventions: Drug Sildenafil Citrate
  • Sponsor: University of Calgary,   Pfizer
Recruiting TRILUMINATE Pivotal Trial
  • Conditions:Tricuspid Regurgitation
  • Interventions: Device Tricuspid valve repair
  • Sponsor:Abbott Medical Devices
Recruiting Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
  • Conditions:Atrial Fibrillation, Stroke, Bleeding
  • Sponsor:Icahn School of Medicine at Mount Sinai, National Heart, Lung, and Blood Institute (NHLBI), Vanderbilt University Medical Center
Recruiting Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension
  • Conditions:Pulmonary Arterial Hypertension
  • Sponsor:Actelion
Recruiting Exercise Training in Patients With Persistent or Permanent Atrial Fibrillation (Exercise-AF)
  • Conditions:Persistent or Permanent Atrial Fibrillation (Exercise-AF)
  • Interventions:Participants will attend on-site moderate-intensity continuous exercise training two times weekly for 12 weeks. Participants will attend on-site high-intensity interval training two times weekly for 12 weeks.
Recruiting Rivaroxaban Post-Transradial Access for the Prevention of Radial Artery Occlusion
  • Interventions: Drug Rivaroxaban 15 MG Oral Tablet [Xarelto]
Recruiting Cardiac Sarcoidosis Randomized Trial
  • Conditions: Cardiac Sarcoidosis,   Sarcoidosis
  • Sponsor: Ottawa Heart Institute Research Corporation,   Canadian Institutes of Health Research (CIHR)
Recruiting The Minimally Invasive Coronary Surgery Compared to STernotomy Coronary Artery Bypass Grafting Trial
  • Sponsor: Ottawa Heart Institute Research Corporation,   London Health Sciences Centre,   Heart Center Leipzig - University Hospital,   Fortis Escorts Heart Institute,   The Methodist Hospital Research Institute,   Carolinas Medical Center,   Gundersen Lutheran Health System,   Jilin Heart Hospital,   Far Eastern Memorial Hospital,   Medtronic,   Apollo Hospitals Enterprise Limited,   Fresno Heart and Surgical Hospital,   Ichinomiya-Nishi Hospital
Recruiting Peer Support for Women With Heart Disease: Women@Heart
  • Conditions: Coronary Heart Disease,   Women's Health
  • Interventions: Behavioral Women@Heart Program
Recruiting Exercise Training in Patients With Persistent or Permanent Atrial Fibrillation
Recruiting Characterization of Arrhythmia Substrate to Ablate Persistent Atrial Fibrillation
  • Interventions: Procedure Catheter ablation
  • Sponsor: Ottawa Heart Institute Research Corporation,   Heart and Stroke Foundation of Canada
Recruiting Biomarker Guided Discharge of Heart Failure Patients
  • Interventions: Other Biomarker guided discharge algorithm
  • Sponsor: Peter Liu,   Genome Canada,   Roche Diagnostics,   Ottawa Heart Institute Research Corporation
Recruiting Sub-Clinical Atrial Fibrillation Biomarker Study
  • Interventions: 
  • Sponsor: Ottawa Heart Institute Research Corporation,   Population Health Research Institute,   Genome Canada,   Bristol-Myers Squibb,   Pfizer,   Medtronic,   Canadian Institutes of Health Research (CIHR)
Recruiting Comparing Hypothermic Temperatures During Hemiarch Surgery
  • Interventions: Procedure Hypothermic circulatory arrest
Recruiting Predicting Development of SCAF in Device Patients
  • Interventions: 
  • Sponsor: Ottawa Heart Institute Research Corporation,   Genome Canada
Recruiting Circulating BDNF in Patients With Atrial Fibrillation Undergoing Catheter Ablation or Exercise Training
Recruiting The Canadian Mitral Research Alliance (CAMRA) Trial CardioLink-2
  • Sponsor: Unity Health Toronto,   Ottawa Heart Institute Research Corporation,   London Health Sciences Centre
Recruiting Cadmium-zinc-telluride (CZT) Imaging of Myocardial Blood Flow (MBF) (SPECT MBF)
  • Interventions: Other single photon emission computed tomography
  • Sponsor: Ottawa Heart Institute Research Corporation,   GE Healthcare
Recruiting Efficacy of Implantable Defibrillator Therapy After a Myocardial Infarction
  • Conditions: Myocardial Infarction,   Sudden Death
  • Sponsor: University of Calgary,   Canadian Institutes of Health Research (CIHR),   Alberta Innovation and Science,   Medtronic,   GE Healthcare
Recruiting Cardiac FDG PET Viability Registry
  • Conditions: Heart Failure,   Ischemic Heart Disease,   Myocardial Dysfunction
  • Interventions: 
  • Sponsor: Ottawa Heart Institute Research Corporation,   Ontario Ministry of Health and Long Term Care
Recruiting Cardiac Sarcoidosis Multi-Center Prospective Cohort
  • Interventions: 
  • Sponsor: Ottawa Heart Institute Research Corporation,   Ontario Ministry of Health and Long Term Care,   Canadian Institutes of Health Research (CIHR)
Recruiting Multicenter Prospective Study of Low-Flow Low-Gradient Aortic Stenosis (TOPAS Study)
  • Sponsor: Laval University,   University Hospital, Brest
Recruiting SodiUm SeleniTe Administration IN Cardiac Surgery (SUSTAIN CSX®-Trial).
  • Sponsor: Daren K. Heyland,   biosyn Arzneimittel GmbH,   Queen's University,   RWTH Aachen University