Wells, Glenn

Overview 

Dr. Glenn Wells is a Medical Physicist in the Department of Nuclear Cardiology at the University of Ottawa Heart Institute, Associate  Professor in the Division of Cardiology at the University of Ottawa and Adjunct Professor in the Department of Physics at Carleton University.  He is also a member of the Ottawa Medical Physics Institute (OMPI).

Background 

Dr. Wells received a BSc in Physics in 1991 from the University of Calgary in Alberta. He received an MSc in Physics (General Relativity) in 1994 and a PhD in Medical Physics (SPECT Imaging) in 1997, both from the University of British Columbia in Vancouver. He pursued post-doctoral research in SPECT imaging at the University of Massachusetts Medical Center in Worcester until 2000, when he took a position as a Medical Physicist with St. Joseph’s Hospital and the Lawson Health Research Institute in London, Ontario. In 2006, he joined the Nuclear Cardiology Department at the Heart Institute. Dr. Wells is a Member of the Board of Directors for the Canadian College of Physicists in Medicine (CCPM) (2010-2016).  He is the Chair of the Awards sub-committee of the Nuclear and Medical Imaging Sciences Council (NMISC) – IEEE Nuclear and Plasma Society (2014, 2015) and has been a member of the Imaging Committee of the Canadian Organization of Medical Physicists since 2012. In addition, he is a member of Working Group 2 (Nuclear Medicine Instrumentation) of the International Electrotechnical Commission Technical Committee 62, Subcommittee 62C (2015) and a member of the Editorial Board of the Journal of Nuclear Cardiology.

Research & Clinical Interests 

Dr. Wells’ research interests are in the physics of multimodality imaging with nuclear medicine: the combination of multislice X-ray computed tomography (CT) with single-photon emission computed tomography (SPECT) and positron emission tomography (PET). More specifically, he is interested in the modification of reconstruction algorithms to more accurately correct for attenuation, scatter, cross-talk, camera resolution, and physiological motion. He is also interested in applications of dynamic SPECT with dedicated cardiac SPECT cameras and dose reduction in nuclear medicine. He is applying this research in the fields of small-animal SPECT/CT and cardiac clinical SPECT.

Publications 

See current publications list at PubMed.
See Research Gate profile

Selected publications:

  1. R. Timmins, R. Klein, J. Petryk, B. Marvin, L. Wei, R.A. deKemp, T.D. Ruddy, R.G. Wells, Reduced dose measurement of absolute myocardial blood flow using dynamic SPECT imaging in a porcine model. Med. Phys. 2015 Sep;42(9):5075
  2. T.L. Miao, V. Kansal, R.G. Wells, I. Ali, T.D. Ruddy, B.J.W. Chow, Adopting New Gamma Cameras and Reconstruction Algorithms: Do we need to re-establish normal reference values? J Nucl Cardiol [EPub Sept 2015].
  3. R.G.Wells, L. Wei, J. Lockwood, Y. Duan, B. Marvin, R. Timmins, K. Soueidan, C. Bensimon, P. Fernando, T.D. Ruddy, Flow-dependent uptake of I-123-CMICE-013, a novel SPECT perfusion agent, compared to standard tracers. J Nucl Med 2015; 56:764-770.
  4. J.H. Strydhorst, R.G. Wells, Effects of CT-based attenuation correction on rat microSPECT images on relative myocardial perfusion and quantitative tracer uptake. Med Phys 2015; 42(4):1818-1824.
  5. R. Timmins, T.D. Ruddy, R.G. Wells, Patient position alters attenuation effects in multi-pinhole cardiac SPECT Med Phys 2015; 42(3):1233-1240.
  6. A. Pourmoghaddas, K. Vanderwerf, T.D. Ruddy, R.G. Wells, Scatter correction improves concordance in SPECT MPI with a dedicated cardiac SPECT solid state camera. J Nucl Cardiol, 2014; 22(2):334-343.
  7. E.J. Orton, I. Al Harbi, R. Klein, R.S.B. Beanlands, R.A. deKemp, and R.G. Wells, Detection and severity classification of extra-cardiac interference in 82Rb PET myocardial perfusion imaging. Med. Phys. 2014; 41, 102501 (11 pages).
  8. R.G. Wells, R. Timmins, R. Klein, J. Lockwood, B. Marvin, R.A. deKemp, and T.D. Ruddy, Dynamic SPECT measurement of Absolute Myocardial Blood Flow in a Porcine Model. J Nucl Med 2014; 55:1685-1691.
  9. M. Lalonde, R.G.Wells, D. Birnie, T.D. Ruddy, and R.Wassenaar, Development and optimization of SPECT gated blood pool cluster analysis for the prediction of CRT outcome. Med Phys 2014; 41(7):072506.
  10. J.H. Strydhorst, R.G. Wells, Quantitative Measurement of In Vivo Tracer Concentration in Rats with Multiplexed Multi-pinhole SPECT. IEEE Trans Nucl Sci 2014; 61(3):1136-1142.

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