Chan, Kwan-Leung

Overview 

Dr. Kwan-Leung Chan is a Cardiologist at the University of Ottawa Heart Institute and The Ottawa Hospital. He is also Professor in the Department of Medicine at the University of Ottawa.

Background 

Dr. Chan earned a BSc, MSc and MD from the University of Manitoba in Winnipeg. After doing his internship at the Health Science Centre in Winnipeg, he did residencies in Internal Medicine at the Toronto East General Hospital and at the University of Ottawa. In 1982, he was named Chief Resident of Internal Medicine at the National Defence Medical Centre in Ottawa, and in 1984, he became Chief Resident in Cardiology at the Heart Institute.

He was certified as a Fellow of the Royal College of Physicians and Surgeons of Canada (FRCPC) in Internal Medicine in 1983 and Cardiology in 1984.

Dr. Chan sits on the Executive Committee of the Canadian Society of Echocardiography and is a member of the Board of Directors of the American Society of Echocardiography.

Research & Clinical Interests 

Dr. Chan’s research interests include valvular heart disease, infective endocarditis and aortic diseases. He has a special interest in the application of ultrasound in the study of cardiac structure and function, and has been actively involved in continuing medical education in this area.

Publications 

LATEST PUBLICATIONS

  • Chan KL, Morin J, Veinot JP. Unusual cause of sudden death in a young patient with atrioventricular septal defect. Can J Cardiol (Images in Cardiology) 2009 Jan;25(1):e19.
  • Abraham A, Chow B, Chan K, Ruddy TD, Beanlands RS. A systematic review and meta-analysis of the impact of myocardial viability by echocardiography on survival after revascularization or medical management in patients with ischemic cardiomyopathy. Can J Cardiol Oct 2008;24(Suppl E):253E.
  • Allan R, Hynes M, Burwash IG, Veinot JP, Chan KL. Coronary artery complications in infective endocarditis. Ann Thorac Surg 2008 Oct;86(4):1381.
  • Stewart RL, Chan K, Beauchesne L, Peters GL, Ascah K, Hay KM, Burwash IG. Can BNP levels predict exercise capacity or functional impairment in patients with asymptomatic severe aortic stenosis? Can J Cardiol Oct 2008;24(Suppl E):319-320E.
  • Embil JM, Chan KL. The American Heart Association 2007 endocarditis prophylaxis guidelines: a compromise between science and common sense. Can J Cardiol 2008 Sep;24(9):673-675.
  • Mussivand T, Alshaer H, Haddad H, Beanlands DS, Beanlands RS, Chan KL, Higginson LA, Leenen F, Ruddy T, Messan T, Silver MA. Thermal therapy: a viable adjunct in the treatment of heart failure? Congest Heart Fail 2008;14:180-186.

PAPERS IN REFEREED JOURNALS

  • Chan K, Wiseman C. A new colonial type of N. Gonorrhoeae. Brit J Vener Dis 1975;51:251-6.
  • Chan K, Wiseman G, Caird J. Cultivation of Type I N. Gonorrhoea in liquid media. Brit J Vener Dis 1975;51:382-6.
  • Chan K, Davies R, Chambers J. Coronary Thrombosis and subsequent lysis after a marathon. J Am Coll Cardiol 1985;4:1322-25.
  • Chan K, Cruise C. Problems in diagnosis of bilateral obstruction of bronchi by foreign bodies. Can Med Assoc 1982;127:870-6.
  • Currie P, Seward J, Chan K, et al. Continuous wave Doppler determination of right ventricular pressure: a simultaneous Doppler-catheterization study in 127 patients. J Am Coll Cardiol 1985;6:750-6.
  • Davies R, Koshal A, Jindal S, Walley V, Green M, Morton B, Chan K, et al. University of Ottawa Heart Institute Transplant Program. The Journal of Heart Transplantation 1986;5:1, 57:58.
  • Klein A, Chan K, Walley V. A new paraspinal window in the echocardiographic diagnosis of descending aortic dissection. American Heart Journal. 1987;114(4):902-904.
  • 8. Chan K, Callahan J, Seward J, Jamil A, Tajik A. Marfan syndrome diagnosed in patients 32 years of age and older. Mayo Clinic Proc 1987;62:589-594.
  • 9. Chan K, Currie P, Seward J, Hagler D, Mair D, Tajik A. Comparison of three Doppler ultrasound methods in the prediction of pulmonary artery disease. The Journal of the American College of Cardiology, 1987;9:549-554.
  • Chan K, Nishimura R, Tajik A. Doppler demonstration of the mechanism of mitral regurgitation mimicking aortic stenosis. The Canadian Journal of Cardiology, 1988;4(3):130 3.
  • Chan K. Transesophageal echocardiography for assessing cause of hypotension after cardiac surgery. The American Journal of Cardiology. 1988; vol. 62:1142-1143.
  • Chan K. Comprehensive assessment of cardiac anatomy in anesthetized patients by transesophageal echocardiography. The Canadian Journal of Cardiology. 1988;8:397-401.
  • Chan K. Noninvasive assessment of prosthetic heart valves. The Canadian Journal of Cardiology. 1988;8:417-421
  • Pipe A, Chan K, Rippe J. Asymptomatic heart murmur in a professional football player. The Physician and Sports medicine. 1988;16(11)November.
  • Kafka H Chan K, Leach AJ. Asymptomatic aortic-left ventricular tunnel in adulthood. Am J Cardiol 1989;63(13) 897-1024.
  • Tesky R, Chan K, Beanlands DS. Diverticulum of the mitral valve complicating bacterial endocarditis. American Heart Journal. 1989;118(5)(1):1063-1065.
  • Dzavik V, Lemay M, Chan K. Echocardiographic diagnosis of an aortic coronary bypass graft aneurysm. A Heart J 1989;118(3):619-621.
  • Zhang B, Pipe A, Chan K, The effect of marathon race on the cardiac structure, function and the serum enzymes in the elderly. Chinese Journal of Sports Medicine. 1989;9:76-79.
  • Chan K, Marquis J-F, Ascah K, Morton B, Baird M. Role of transesophageal echocardiography in percutaneous balloon mitral valvuloplasty. Echocardiography 1990;7:115-123.
  • Turabian M, Chan K. Rupture of mitral chordae tendineae resulting from blunt chest trauma: Diagnosis by transthoracic and transesophageal echocardiography. Can J Cardiol 1990;6(5):3-5.
  • Cohen G, Chan K. Physical examination and echo Doppler study in the assessment of femoral arterial complications following cardiac catheterization. Catheterization and Cardiovascular Diagnosis 1990;1(21):137-143.
  • Cohen G, Chan K, Walley V. Anatomic correlations of the long-axis views in biplane transesophageal echocardiography. Am J Card. 1990;66:1007-1012.
  • Giannoccaro P, Marquis J-F, Chan K, Walley V, Chambers R. Aortic dissection presenting as upper airway obstruction. Chest, 1991;99(1):256-258.
  • Cohen G, Chan K. Biplane transesophageal echocardiography: Clinical applications of the long-axis plane. J Am Soc Echocardiogr 1991;4:155-163.
  • Giannoccaro P, Ascah K, Sochowski R, Chan K, Ruddy T. Spontaneous drainage of paravalvular abscess diagnosed by transesophageal echocardiography. J Am Soc Echocardiogr. 1991;4:397-400.
  • Pachulski R, Weinberg A, Chan K. Aortic aneurysm in functionally normal or minimally stenotic bicuspid aortic valve. Am J Cardiol 1991;67(8):781-782.
  • Chan K. Usefulness of transesophageal echocardiography in the diagnosis of conditions mimicking aortic dissection. Am Heart J 1991;122:495-504.
  • Dzavik V, Cohen G, Chan K. Role of transesophageal echocardiography in the diagnosis and management of prosthetic valve thrombosis. J Am Coll Cardiol 1991;18,1829-33.
  • Sochowski R, Chan K, Ascah K, Bedard P. Improved accuracy of transesophageal versus transthoracic echocardiography for the detection of flail myxomatous mitral valves. Am J Cardiol. 1991;67(15):1251-1255.
  • Black M, Calvin J, Chan K, Walley V. Paradoxical air embolism in the absence of an intracardiac defect. Chest 1991;99:754-55.
  • Chan K, Cohen G, Sochowski R, Baird M. Complications of transesophageal echocardiography in ambulatory adult patients: Analysis of 1500 consecutive patients. J Am Soc Echocardiogr, 1991;4:577-82
  • Taylor D, Chan K, Higginson L. Complementary role of two-dimensional and Doppler echocardiography in the diagnosis of left ventricular free wall rupture. J Am Soc Echocardiogr 1992;5(1):93-95.
  • 33. Melendez L, Chan K, Cheung P, Sochowski R, Wong S, Austin T. Incidence of bacteremia in transesophageal echocardiography: A prospective study of 140 consecutive patients. J Amer Coll Cardiol. 1991, 18;1650-4.
  • Giannoccaro P, Ascah K, Chan K. Left atrial mass produced by extensive mitral annular calcification. J Am Soc Echocardiogr 1991;4:619-22.
  • Chan K. Impact of Transesophageal echocardiography on the management of patients with aortic dissection. Chest 1991;101(2):406-410.
  • Cohen G, Klein A, Chan K, Stewart W, Salcedo E. Transesophageal echocardiographic diagnosis of right-sided cardiac masses in patients with central lines. Am J Cardiol 1992;70:925-929.
  • Rattes M, Sochowski R, Baird M, Chan K. Intraoperative transesophageal echocardiographic demonstration of mitral leaflet tear following resection of a subaortic membrane. Can J Cardiol 1992;8(8):785-787.
  • Sochowski R, Chan K. Implication of negative results on a monoplane transesophageal echocardiographic study in patients with suspected infective endocarditis. J Am Coll Cardiol, 1993 21(1):216-21.
  • Pachulski R, Chan K. Progression of aortic valvular dysfunction in 51 adult patients with congenital bicuspid aortic valve: assessment and followup by Doppler echocardiography. British Heart Journal 1993;69(3):237-240.
  • Giannoccaro P, Sochowski R, Morton B, Chan K. Complementary role of transesophageal echocardiography in the assessment of coronary artery anomalies. British Heart Journal 1993 (70):70-4.
  • Yvorchuk K, Chan K. Application of transthoracic and transesophageal echocardiography in the diagnosis and management of infective endocarditis. J Am Soc Echocardiogr 1994;7(3 Part 1):294-308.
  • Antecol D. Chan K. Congentially bicuspid aortic valve: Diagnosis, Complications, and progression of aortic valvular dysfunction. Primary Cardiology 1994;20(3):15-18.
  • Antecol D, Walley V, Chan K. Massive acute thrombosis of the descending thoracic aorta in heparin-associated thrombocytopenia and thrombosis. J Am Soc Echocardiogr 1994;7:550-2.
  • Walley V, Chan K, Antecol D. Congenitally bicuspid aortic valves: A study of an atypical variant with fenestrated raphe. Can J Cardiol 1994;10(5):535-542.
  • Yvorchuk K, Davies RA, Chan K. Measurement of left ventricular ejection fraction by acoustic quantification and comparison with radionuclide angiography. Am J Cardiol 1994;74:1052-1056.
  • Yvorchuk K, Sochowski R, Chan K. A prospective comparison of the multiplane probe with the biplane probe in structure visualization and Doppler examination during transesophageal echocardiography. J Am Soc Echocardiog 1995;8:111-20.
  • Taskforce (Chan K, Chairman) Guidelines from the Canadian Cardiovascular Society and the Canadian Hypertension Society on the echocardiographic determination of left ventricular mass. Can J Cardiol 1995;11(5):391-5.
  • 48. Cohen JL, Chan K, Jaarsma W, Bach DS, Muller DWM, Starling MR, Armstrong WF. Arbutamine echocardiogaphy: Efficacy and Safety of a new pharmacological stress agent to induce myocardial ischemia and detect coronary artery disease. Am Col Cardiol 1995;26(5):1168-75.
  • Gilchrist D, Chan K, Marfan Syndrome: Experience of the Multiplicinary Canadian Marfan Association national Clinic. Annals RCPSC 1995;28(6):348-52.
  • Sochowski RA, Yvorchuk KJ, Yang Y, Rattes MF, Chan K. Dobutamine and Dipyridamole stress echocardiography is patients with a low incidence of severe coronary artery disease. J Am Soc Echocardiogr 1995;8:482-7.
  • 51. Cohen G, White M, Sochowski RA, Klein AL, Patrick D, Bridge MS, Stewart WJ, Chan K. Reference Values for Normal Adult Transesophageal Echocardiographic Measurements. J Am Soc Echocardiogr 1995;8:221-30.
  • Dumesnil JG, Dion D, Yvorchuk K, Davies RA, Chan K. A New, simple and accurate method for determining ejection fraction by Doppler echocardiography. Can J Cardiol 1995;11(11):1007-14.
  • 53. Stroke Prevention in Atrial Fibrillation Investigators, (Chan K, Co-Investigator. Risk Factors for Thrombooembolism During Aspirin Therapy in Patients with Atrial Fibrillation: The stroke prevention in Atrial Fibrillation Study. J Stroke Cerebrovasc Dis 1996;5:147-57.
  • Yvorchuk K, Sochowski R, Chan K. Sonicated albumin in exercise echocardiography: Technique and Feasibility to enhance endocardial visualization. J Am Soc Echocardiogr 1996;9(4):462-9.
  • Echocardiography Subcommittee of the Canadian Cardiovascular Society Committee on Standards (Chan K, Chair). Standards for adult echocardiographic training. Can J Cardiol 1996;12(5):473-6.
  • Stroke Prevention in Atrial Fibrillation Investigators, Committee on Echocardiography (Chan K, Co-investigation): Transesophageal echocardiography in atrial fibrillation: Standards for acquisition and interpretation and assessment of inter-observer variability. J Am Soc Echocardiogr 1996;9:556-66.
  • Stroke Prevention in Atrial Fibrillation Investigators: Chan K, (Co-Investigator). Superiority of adjusted-dose Warfarin over low-intensity, fixed-dose Warfarin plus aspirin for high-risk patients with atrial fibrillation: The Stroke Prevention in Atrial Fibrillation III randomized clinical trial. Lancet 1996;348:633-8.
  • Tam JW. Chan K. Unmasking the origin of a pseudo-left atrial mass. Circulation. (letter) 1996;94(11)2990-1.
  • Rakowski H, Appleton C, Chan K, Dumesnil JG, Honos G, Jue J, Koilpillai C, Lepage S, Martin RP, Mercier LA, O’Kelly B, Prieur T, Sanfilippo A, Sasson Z, Alvarez N, Pruitt R, Tompson C, Tomlinson C. Canadian consensus recommendations for the measurement and reporting of diastolic dysfunction by echocardiography. J Am Soc Echocardiog 1996;9(5):736-60.
  • Stroke Prevention in Atrial Fibrillation Investigators, (Chan K, Co-investigator): The Stroke Prevention in Atrial Fibrillation III study: Rationale design and patient features. J Stroke Cerebrovasc Dis. 1997;6:1-4.
  • Tam JW, Chan K. Feasibility and complications of single-plane and biplane versus multiplane transesophageal imaging: A review of 2947 consecutive studies. Can J of Cardiol 1997;13(1):81-4.
  • Huntington K, Hunter Alasdair GW, Chan K. A prospective study to assess the frequency of familial clustering of congenital bicuspid aortic valve. J Am Coll Cardiol 1997;30(7):1809-12 .
  • The Stroke Prevention in Atrial Fibrillation Investigators Committee on Echocardiography, Chan K Chairman Writing Committee. Transesophageal echocardiographic correlates of thromboembolism in high-risk patients with nonvalvular atrial fibrillation. Annals 1998;128(8):639-47.
  • Chan K, Burwash I. Unusual structural abnormality in a biplane transesophageal transducer with normal imaging function. Am Soc Echocardiog 1998;11(3):310-2.
  • Tam J, Masters R, K Chan. Late sequelae of traumatic aortic rupture. Circulation 1998;97:932-3.
  • Tam J, Masters R, Burwash I, Mayhew A, Chan K. Management of patients with mild aortic stenosis undergoing coronary artery bypass surgery. Annals Thoracic Surgery 1998;65:1215-9.
  • Stroke Prevention in Atrial Fibrillation Investigators, Chan K (Co-investigator). Identifying AF Patients at Low Risk for Stroke. JAMA 1998;279:1273-7.
  • Chan K, Halperin J. Transesophageal Echocardiography in High-Risk Patients with Atrial Fibrillation. Annals 1998;129(9):748, Letter.
  • Chan K, Stinson, WA, Veinot JP. Reliability of Transthoracic Echocardiography In The Assessment of Aortic Valve Morphology: Pathological Correlation In 178 Patients. Can J Cardiol 1999;15(1):48-52.
  • Tam JW, Antecol D, Kim HH, Yvorchuk KJ, Chan K. Low Dose Dobutamine Echocardiography In The Assessment Of Contractile Reserve To Predict The Outcome Of Valve Replacement For Chronic Aortic Regurgitation. Can J Cardiol 1999;15(1):73-9.
  • Hynes MS, Tam JL, Burwash IG, Chan K. Predictive value of pulmonary venous flow patterns in detecting mitral regurgitation and left ventricular abnormalities. Can J Cardiol 1999;15(6):665-70.
  • Fagan SM, Chan K. Pericardiocentesis–Blind No More! (Editorial). Chest 1999;116(2):275-6.
  • Kim HH, Tam JW, Chan K. A prospective transesophageal echocardiographic study to assess a new type of left atrial spontaneous contrast at rest and during respiratory manoeuvres. Can J Cardiol 1999;15(11):1217-22.
  • Chan K, Abdulla A. Giant coronary sinus and absent right superior vena cava. Heart 2000;83:704.
  • Chan K. Mitral valve aneurysm in endocarditis. (Letter) Circulation 2000;102:e102.
  • Chan K. A continuous murmur after surgery for dissecting ascending aortic aneurysm. Ann Thorac Surg 2000;69:1929-31.
  • Fagan SM, Chan K. TEE risk factors for stroke in nonvalvular atrial fibrillation. Echocardiography 2000;17:365-72.
  • Fagan SM, Veinot JP, Chan K. Residual sinus venous atrial septal defect following surgical closure of atrial septal defect. J Am Soc Echocardiog 2001;14:738-41.
  • Burwash IG, Dickinson A, Teskey RJ, Tam JW, Chan KL. Aortic valve area discrepancy by Gorlin equation and Doppler echocardiography continuity equation: Relationship to flow in patients with valvular aortic stenosis. Can J Cardiol 2000;16:985-92.
  • Chan K, Veinot J, Leach A, Bedard P, Smith S, Marquis J-F. Diagnosis of left atrial sarcoma by transvenous endocardial biopsy. Can J Cardiol 2001;17(2):206-8.
  • Isotalo PA, Chan KL, Rubens F, Beanlands DS, Auclair F, Veinot JP. Prosthetic valve fungal endocarditis due to histoplasmosis. Can J Cardiol 2001;17(3):297-303.
  • Chan K, Ghani M, Woodend K, Burwash I. Case-controlled study to assess risk factors for aortic stenosis in congenitally bicuspid aortic valve. Am J Cardiol; Sept 2001;88:690-692.
  • Chan K. Early clinical course and long-term outcome of patients with infective endocarditis complicated by perivalvular abscess. CMAJ 2002;167(1):19-24.
  • Hynes MS, Veinot JP, Chan KL. Occurrence of a second primary papillary fibroelastoma. Can J Cardiol 2002;18(7):753-756.
  • Burwash IG, Hay K, Chan K, Hemodynamic stability of valve area, valve resistance, and stroke work loss in aortic stenosis: a comparative analysis. J Am Soc Echocardiogr. 2002 Aug;15(8):814-22.
  • Chan K, Tang ASL, Achilli A, et al. Functional and echocardiographic improvement following multi-site biventricular pacing for congestive heart failure. Can J Cardiol. 2003 Mar 31;19(4):387-90.
  • Chan K. Echocardiography in right sided endocarditis (Editorial) Clin Invest Med. 2002 Aug;25(4):134-6.
  • Tardif JC, Dore A, Chan KL, Fagan S, Honos G, Marcotte F, Yu E, Siu S, Dumesnil J, Arsenault M, Koilpillai C, D'onofrio F. Economic impact of contrast stress echocardiography on the diagnosis and initial treatment of patients with suspected coronary artery disease. J Am Soc Echocardiogr. 2002 Nov;15(11):1335-45.
  • Campbell JALJ, Higginson LAJ, Chan KL, Woulfe JM, Veinot JP. Acute myocardial infarction in a young man with dilated cardiomyopathy: clinicopathological correlation. Can J Cardiol. 2003 March 15;19, No 3. 287-292.
  • Chow B, Tang ASL, Chan K, et al. Prevalence and significance of lead-related thrombi in patients with implantable cardioverter defibrillators. Am J Cardiol 2003 Jan;91:88-90.
  • Campbell N, Rosaeg OP, Chan KL. Anaesthesia management of a parturient with pulmonary stenosis and aortic incompetence for caesarean section. Br K Anaesth 2003 Feb;90(2):241-3.
  • Chan KL, Tang ASL, Achilli A, Sassara M, Bocchiardo M, Gaita F, Cavaglia S, Hilpisch K, Hill M, Gras D. Functional and echocardiographic improvement following multisite biventricular pacing for CHF. Can J Cardiol 2003;19(4):387-390.
  • Beauchesne LM, Veinot JP, Brais MP, Burwash IG, Chan KL. Acute aortic intimal tear without a mobile flap mimicking an intramural hematoma. J Am Soc Echocardiogr. 2003 Mar;16(3):285-8.
  • Chan KL. Is aortic stenosis a preventable disease? J Am Coll Cardiol. 2003 Aug 20;42(4):593-9.
  • Beauchesne LM, Dekemp R, Chan KL, Burwash IG. Temporal variations in effective orifice area during ejection in patients with valvular aortic stenosis. J Am Soc Echocardiogr. 2003 Sep;16(9):958-64.
  • Chan KL, Dumesnil JG, Cujec B, Sanfilippo AJ, Jue J, Turek MA, Robinson TI, Moher D; Investigators of the Multicenter Aspirin Study in Infective Endocarditis A randomized trial of aspirin on the risk of embolic events in patients with infective endocarditis..J Am Coll Cardiol. 2003 Sep 3;42(5):775-80.
  • Chan KL, Scott N, Veinot JP. Symptoms in Cardiac Myxoma. (Commentary) Chest 2003;123:2408.
  • Kinsara A, Ramadan F, Chan KL. Prevalence and significance of increased intraventricular velocities in healthy elderly subjects. Can J Cardiol 2004 Feb;20(2):201-3.
  • Kurdi M, Beanlands DS, Chan KL, Veinot JP. Nonbacterial thrombotic endocarditis presenting as aortic stenosis with suspected infective endocarditis: Clinicopathological correlation. Can J Cardiol. 2004 Apr;20(5):549-52.
  • Chan KL et al. A randomized trial of aspirin on the risk of embolic events in patients with infective endocarditis: Reply. J Am Coll Cardiol. 2004 Mar 17;43(6):1134-1135.
  • Chan KL, Liu X, Ascah KJ, Beauchesne LM, Burwash IG. Comparison of real-time 3-dimensional echocardiography with conventional 2-dimensional echocardiography in the assessment of structural heart disease. J Am Soc Echocardiogr 2004;17:976-80.
  • Kinsara A, Chan KL. Noninvasive imaging modalities in coarctation of the aorta. Chest 2004 Oct. 126(4): 1016 – 8
  • Salehian O, Chan KL. Should brain natriuretic peptides be measured in patients with aortic valve disease? Eur Heart J. 2005 Mar 21; Eur Heart J. 2005 May;26(10):951-2
  • Salehian O, Chan KL. Impact of three-dimensional echocardiography in valvular heart disease. Curr Opin Cardiol. 2005 Mar;20(2):122-6.
  • Al-Faleh H, Marquis JF, Chan K. Device closure of a patent foramen ovale in a patient with lipomatous hypertrophy of the atrial septum. Can J Cardiol 2005 July;21(9):789-790.
  • Sanfilippo AJ, Bewick D, Chan KL, Cujec B, Dumesnil JG, Honos G, Munt B,
  • Sasson Z, Tam J, Tomlinson C, Aboguddah A, Ahmed S, Ali M, Arsenault M, Ascah K,
  • Ashton T, Baird M, Basmadjian A, Beique F, Blakeley M, Blais MJ, Burggraf G,
  • Burwash I, Cochrane J, Fagan S, Giannoccaro P, Hughes W, Jones A, Jue J,
  • Koilpillai C, Leblanc MH, Londry C, Morgan D, O'reilly M, Sawchuk C, Siu S,
  • Sochowski R, Tremblay G, Welikovitch L, Yu E. Guidelines for the provision of echocardiography in Canada: Recommendations of a joint Canadian Cardiovascular Society/Canadian Society of Echocardiography Consensus Panel. Can J Cardiol. 2005 Jul;21(9):763-80.
  • Wolfsohn AL, So DY, Chan KL, Burwash IG, Hendry P, Veinot JP, Labinaz M. Thrombus of the ascending aorta A rare cause of myocardial infarction. Cardiovasc Pathol. 2005 Jul-Aug;14(4):214-8.
  • Sylvius N, Bilinska ZT, Veinot JP, Fidzianska A, Bolongo PM, Poon S, McKeown
  • P, Davies RA, Chan KL, Tang AS, Dyack S, Grzybowski J, Ruzyllo W, McBride H,
  • Tesson F. In vivo and in vitro examination of the functional significances of novel lamin
  • gene mutations in heart failure patients. J Med Genet. 2005 Aug;42(8):639-47.
  • Chan KL, Teo K. Lipid-lowering therapy in calcific aortic stenosis. N Engl J Med. 2005 Sep 8;353(10):1066-7; author reply 1066-7.
  • Dore A, Houde C, Chan KL, Ducharme A, Khairy P, Juneau M, Marcotte F, Mercier LA. Angiotensin receptor blockade and exercise capacity in adults with systemic right ventricles: a multicenter, randomized, placebo-controlled clinical trial. Circulation. 2005 Oct 18;112(16):2411-6. Epub 2005 Oct 10.
  • Al-Shehri F, Chan KL, Dennie C, Veinot JP. Tuberculous Pericarditis. Current Cardiology Reviews, 2005, I, 165-169.
  • Ruel M, Al-Faleh H, Kulik A, Chan KL, Mesana T, Burwash IG. Prosthesis-patient mismatch after aortic valve replacement predominantly affects patients with pre-existing left ventricular dysfunction: Effect on survival, freedom from heart failure, and left ventricular mass regression. J Thorac Cardiovasc Surg 2006 May;131(5):1036-44.
  • Mahmoud S, Beanlands RS, deKemp R, Chan KL, Beauchesne LM. Native anomalous left coronary artery from the pulmonary artery in an adult: Evidence of impaired coronary flow reserve by rubidium-82 positron emission tomography quantification. Can J Cardiol. 2006 Oct;22(12):1069-70.
  • Little SH, Chan KL, Burwash IG. Impact of Blood Pressure on the Doppler Echocardiographic Assessment of Aortic Stenosis Severity. Heart. 2006 Nov 29;
  • Law A, Chan KL. Surgical referral in symptomatic mitral regurgitation: greater compliance with guidelines is needed. Eur Heart J. 2007 Jun;28(11):1281-2.
  • Chan KL, Teo K, Tam J, Dumesnil JG; Astronomer Investigators. Rationale, design, and baseline characteristics of a randomized trial to assess the effect of cholesterol lowering on the progression of aortic stenosis: the Aortic Stenosis Progression Observation: Measuring Effects of Rosuvastatin (ASTRONOMER) trial. Am Heart J. 2007 Jun;153(6):925-31.
  • Salehian O, Burwash IG, Chan KL, Beauchesne LM. Tricuspid Annular Systolic Velocity Predicts Maximal Oxygen Consumption During Exercise in Adult Patients with Repaired Tetralogy of Fallot. J Am Soc Echocardiogr. 2008 Apr;21(4):342-346.
  • Chan KL, Tam J, Dumesnil JG, Cujec B, Sanfilippo AJ, Jue J, Turek M, Robinson T, Williams K. Effect of long-term aspirin use on embolic events in infective endocarditis. Clin Infect Dis. 2008 Jan 1;46(1):37-41.
  • Jassal DS, Tam JW, Dumesnil JG, Giannoccaro PJ, Jue J, Pandey AS, Joyner CD, Teo KK, Chan KL. Clinical Usefulness of Tissue Doppler Imaging in Patients with Mild to Moderate Aortic Stenosis: A Substudy of the Aortic Stenosis Progression Observation Measuring Effects of Rosuvastatin Study. J Am Soc Echocardiogr. 2008 Apr 10; [Epub ahead of print
  • Jassal DS, Tam JW, Bhagirath KM, Gaboury I, Sochowski RA, Dumesnil JG, Giannoccaro PJ, Jue J, Pandey AS, Joyner CD, Teo KK, Chan KL. Association of mitral annular calcification and aortic valve morphology: a substudy of the aortic stenosis progression observation measuring effects of rosuvastatin (ASTRONOMER) study. Eur Heart J. 2008 Jun;29(12):1542-7.
  • Cunningham KS, Chan KL, Veinot JP. Pathology of isolated atrial infarction: case report and review of literature. Cardiovasc Pathol. 2008;(17):183-185.
  • Mussivand T, Alshaer H, Haddad H, Beanlands DS, Beanlands RS, Chan KL, Higginson LA, Leenen F, Ruddy T, Messan T, Silver MA. Thermal therapy: a viable adjunct in the treatment of heart failure? Congest Heart Fail. 2008;14:180-186.
  • Embil JM, Chan KL. The American Heart Association 2007 endocarditis prophylaxis guidelines: A compromise between science and common sense. Can J Cardiol. 2008 Sep;24(9):673-5.
  • Allan R, Hynes M, Burwash IG, Veinot JP, Chan KL. Coronary artery complications in infective endocarditis. Ann Thorac Surg. 2008 Oct;86(4):1381.
  • Chan KL, Morin J, Veinot JP. Unusual cause of sudden death in a young patient with atrioventricular septal defect. Can J Cardiol (Images in Cardiology). 2009 Jan;25(1):e19.
  • Abraham A, Chow B, Chan K, Ruddy TD, Beanlands RS. A systematic review and meta-analysis of the impact of myocardial viability by echocardiography on survival after revascularization or medical management in patients with ischemic cardiomyopathy. Can J Cardiol. Oct 2008;24(Suppl E):253E.
  • Stewart RL, Chan K, Beauchesne L, Peters GL, Ascah K, Hay KM, Burwash IG. Can BNP levels predict exercise capacity or functional impairment in patients with asymptomatic severe aortic stenosis. Can J Cardiol. Oct 2008;24(Suppl E):319-320E.

ABSTRACTS

  • Chan K, Callahan J, Gordon H, et al. Prognosis of patients with the Marfan's syndrome diagnosed after age 32. American College of Cardiology (1986).
  • Chan K, Tajik. Effect of aortic regurgitation on the Doppler-derived mitral pressure halftime. American College of Cardiology (1986).
  • Chan K, Currie P, Sewart J, et al. Comparison of three Doppler methods in the prediction of pulmonary artery pressure. American College of Cardiology. (1986).
  • Chan K, Davies R, Barrie M, Keon W. Incidence of valvular Aortic involvement in ankylosing spondylitis: An echo-Doppler study. Clinical and Investigative Medicine. 1987:10(4) Abst R516;B127.
  • Chan K, Barrie M, Hay K, Andrews J. Color flow Doppler improves the accuracy of mitral area measurement by planimetry. Clinical and Investigative Medicine. 1987;10(5)Abst 120;C58.
  • Chan K, Niznick J, Laramee L, Andrews J, Baird M. Echocardiographic diagnosis of left ventricular thrombus: Importance of the short axis apical view. Clinical and Investigative Medicine. 1987:10(4)Abst C45;B54.
  • Chan K, Tang A, Thompson J, Kraag G, Habibi H, Higginson L. Aortic involvement in ankylosing spondylitis: An echo-Doppler study. Clinical and Investigative Medicine. 1987:10(4) Abst R516;B127.
  • Chan K, Pipe A, Barrie M. Acute effect of marathon running on left ventricular function. Medicine and Science in Sports and Exercise. Suppl. April 1987:583.
  • Chan K, Blakley M. Evaluation of patients following cardiac surgery using transesophageal echocardiography: Initial experience. Clinical and Investigative Medicine. 1987:10(5) Abst 55;C42.
  • Chan K, Barrie M, Hay K, Andrews J. Does mitral annual calcification cause mitral valvular dysfunction in the elderly. Clinical and Investigative Medicine. 1988;11(4);C51.
  • Chan K. Analysis of 115 consecutive transesophageal echocardiographic studies in ambulatory patients. Clinical and Investigative Medicine, 1988;11(5):D38.
  • Chan K. Superiority of transesophageal echocardiography in the evaluation of mitral dysfunction. Clinical and Investigative Medicine, 1988:11(5);D38.
  • Chan K, Bedard P, Goldstein W, Koshal A, Keon W. Intraoperative assessment of mitral valve repair by transesophageal echocardiography. Clinical and Investigative Medicine, 1988;11(5);D75.
  • Chan K, Diagnosis of aortic dissection by transesophageal echocardiography. Clinical and Investigative Medicine. 1988:11(5) Abst 12;D34.
  • Chan K, Pipe A, DeBold A, Atrial natriurtic hormone in marathon running. Medicine and Science in Sports and Exercise. 1988:20(2) April (Suppl):232.
  • Chan K, Pipe A. Asymptomatic heart murmur - Pro football player. Medicine and Science in Sports and Exercise. 1988;20(2) April(Suppl):164.
  • Chan K, Ascah K, Baird M. Comparison of Medtronic-Hall mechanical valve with Ionescu-Shiley tissue valve: An echo Doppler study. Echocardiography 1988:5(4);417-421.
  • Chan K. Superiority of transesophageal echocardiography in the evaluation of mitral dysfunction. European Heart Journal. 1988:(9) Abst (Suppl 1);28.
  • Chan K, Pipe A, DeBold A. Atrial Natriuretic hormone in marathon running. European Heart Journal. 1988:(9) Abst. (Suppl 1);379.
  • Chan K. Diagnosis of aortic dissection by transesophageal echocardiography. Chest 1988:94;775.
  • Chan K. Analysis of 125 consecutive transesophageal echocardiographic studies in ambulatory patients. Circulation 1988;78(4):II-440.
  • Chan K. Transesophageal echocardiography in the management of intubated cardiac patients. Circulation 1988:78(4);II-298.
  • Chan K. Aortic disease in suspected aortic dissection:A transesophageal echo study. A new window to the heart. Proceedings of the International Symposium on Transesophageal Echocardiography. 1988;Nov 30 - Dec 2:10
  • Chan K. Aortic disease in suspected aortic dissection. A transesophageal echo study. Circulation 1988:78:298.
  • Pipe A, Chan K. A heart murmur and a normal ECG in a college football player. Medicine and Science in Sports and Exercise. 1988;20(2) April (Suppl):164.
  • Bedard P, Chan K. Carpentier ring and mitral valve repair: short term results. Clinical and Investigative Medicine 1989;12(5):C-62 (116).
  • Chan K. Transesophageal color flow Doppler is reliable in intra-operative evaluation of valvular regurgitation. Clinical and Investigative Medicine 1989;12(5):C65 (131).
  • Chan K. Transesophageal echocardiography is crucial in the evaluation of patients with endocarditis. Clinical and Investigative Medicine 1989;12(5):C66 (133)
  • Chan K. Diagnosis of cardiac source of emboli by transesophageal echocardiography. Clinical and Investigative Medicine 1989;12(5):C66 (134).
  • Grigg, L, Daniel L, Chan K, Weisel R, Baird R, Rakowski H. Transesophageal echocardiography (TEE) improves detection of residual abnormalities after ascending aortic surgery (AAS). Clinical and Investigative Medicine. 1989;12(5): C66 (135).
  • Chan K. Cardiac chamber size and wall thickness in fetuses of diabetic mothers. Clinical and Investigative Medicine. 1989:12(5):C100 (272).
  • Chan K. Importance of transesophageal echocardiography in the management of endocarditis. Clinical and Investigative Medicine 1989;12(4):R-346.
  • Teskey R, Marquis, J-F, Chan, K, Morton B, Gordon J. Does previous surgical commissurotomy affect the results of percutaneous balloon mitral valvuloplasty? Clinical and Investigative Medicine, 1990;13(5):C 53 (72).
  • Cohen G, Klein A, Chan K, Stewart W, Salcedo E. Delineation of right heart masses by transesophageal echocardiography in patients with central venous lines. Clinical and Investigative Medicine, 1990;13(5):C67 (129).
  • Chan K, Walley V. Pathologic correlations of transesophageal echocardiographic findings in degenerated bioprosthetic valves. Clinical and Investigative Medicine, 1990;13(5) C67 (131)
  • Sochowski R, Ascah K, Chan K. Detection of flail myxomatous mitral valve by transthoracic and transesophageal echocardiography. Clinical and Investigative Medicine, 1990;13(5):C87 (211).
  • Chan K, Daniel L, Rakowski H, Ascah K, Baird M. Transesophageal echocardiography is crucial in the evaluation of patients with endocarditis. Circulation 1989;80(4):II-668.
  • Chan K, Walley V. Transesophageal Echocardiography in the detection of cusp tears in degenerated bioprosthetic valves. Clinical and Investigative Medicine, 1990;13(5): C88 (212).
  • Chan K, Cohen G, Beanlands D. Evaluation of physical signs in the diagnosis of vascular complications following femoral arterial cannulation. Clinical and Investigative Medicine, 1990;13(4): B12(45).
  • Pachulski R, Chan K. Progression of valvular dysfunction in bicuspid aortic valve. Journal of American Society of Echocardiography. 1990;3(3):218.
  • Greigg L, Daniel L, Chan K, Wiesel R, Baird R, Rakowski H. Transesophageal echocardiography (TEE) improves detection of residual abnormalities after ascending aortic surgery (AAS). J Am Soc Echo 1990;3(3):223.
  • Chan K. Cohen G, Dore S, Left atrial spontaneous contrast in mitral stenosis - A transesophageal echo study. J Am Soc Echo. 1990;3(3):212.
  • Chan K, Walley V. Pathologic correlations of transesophageal echocardiographic findings in degenerated bioprosthetic valves. Circulation 1990 Suppl III; 82(4):III-44(0173).
  • Chan K, Baird M. Failed attempts and complications of transesophageal echocardiography in 1000 ambulatory patients. Circulation 1990 Suppl III; 82(4):III-30(0120).
  • Cohen G, Chan K. Comparison of transesophageal echocardiographic and angiography in the assessment of mitral regurgitation. Circulation 1990 Suppl III; 82(4):III-0550 (2185).
  • Chan K, Cheung P, Wong S, Sochowski R, Austin T, Melendez L. Transesophageal echocardiography (TEE) and bacteremia. Circulation 1990 Suppl III;82(4):III-244 (0970).
  • Cohen G, Klein A, Chan K, Schiavone W. Transesophageal echocardiographic imaging of right heart masses in patients with central venous lines. Circulation 1990 Suppl III;82(4):III-32 (0125).
  • Cohen G, Klein A, Sochowski R, Chan K, Klein A, Stewart W. Normal reference measurements obtained from transesophageal echocardiographic studies. Circulation 1990 Suppl III;82(4):III-30 (0118).
  • Mayhew A, Chan K, Dafoe W, Cupper L. Transesophageal echocardiography: A new method of evaluating cardiac response to weight lifting - A case study. J Cardiopul rehab 1990 10:375.
  • Chan K, Walley V. Accuracy of transesophageal echocardiographic detection of cusp tears in degenerated bioprosthetic valves. JACC 1991;17(2):371A.
  • Chan K, Sochowski R, Ascah K, Baird M. Does a negative transesophageal echocardiographic study rule out infective endocarditis? JACC 1991;17(2):371A.
  • Chan K, Sochowski R. Comparison of transesophageal continuous-wave Doppler with transthoracic doppler in the assessment of mitral stenosis. Can J Cardiol 1991;7(Suppl A):64A (Abstr-23).
  • Chan K, Sochowski R. Management and outcome of patients with prosthetic valvular thrombosis diagnosed by transesophageal echocardiography. Can J Cardiol 1991;7(Suppl A):92A (Abstr-119).
  • Giannoccaro P, Chan K, Sochowski R, Ascah K, Habibi H, Baird M. Does age affect the yield of transesophageal echocardiography in the detection of a potential cardiac source of immobilisation? Can J Cardiol 1991;7(Supple A):108A (Abstr-182).
  • Chan K. Diagnosis of conditions mimicking aortic dissection -A unique role of transesophageal echocardiography. Can J Cardiol 1991;7(Supple A):108A (Abstr-183.)
  • Taylor D, Chan K. Transesophageal echocardiographic identification of two types of left atrial spontaneous contrast in patients with mitral mechanical valves. Circulation 1991; Supp II 84(4):II-161 (Abstr-0644).
  • Tang T, Robblee J, Nathan H, Wynands J, Eagle C, Belenkie I, Chan K, Tyberg J. The pericardium and left ventricular diastolic pressure-volume relation and filling: An intraoperative study. Can J Anaesth 1991;38(4):Part II.
  • Pachulski R, Chan K. Progression of aortic valvular dysfunction in bicuspid aortic Valve: Assessment and followup by Doppler echocardiography. Clinical and Investigative Medicine, 1992;15(suppl)(4):A14(66) Abstract.
  • Sochowski R, Tang, A, Chan K, Baird M. Greater importance of atrial contraction with increasing degrees of cardiac tamponade. Clinical and Investigative Medicine, 1992; 15(suppl 4):A14(57) Abstract.
  • Bedard P, Chan K, Sochowski R. The importance of intra-operative assessment of mitral valve repair. Cdn J Cardiol 1992 Aug;8(B):284.
  • Labinez M, Chan K, Tang A. Transesophageal Doppler parameters & atrial electrogram during atrial fibrillation-flutter: Prediction of Recurrence After Cardioversion. Cdn J Cardiol 1992 Aug;8(B):66B.
  • Auclair R, Chan K, Masters R. Saginur R. Infective endocarditis: Potential role of sequential echocardiographic studies. Cdn J Cardiol 1992;8(B):66B.
  • Chan K, Sochowski R. Management and outcome of patients with prosthetic valvular thrombosis diagnosed by transesophageal echocardiography. 1992;19(3):39A(714-6
  • Chan K, Sochowski R. Comparison of transesophageal continuous wave Doppler with transthoracic Doppler in the assessment of mitral stenosis. 1992;19(3):201A(764-3).
  • Chan K, Sochowski R. Conservative medical treatment can be appropriate in the management of perivalvular abscess: Diagnosis and followup by transesophageal echocardiography. Can J Cardiol 1993;9:(Suppl E) Abs 24:25E.
  • Yvorchuk K, Davies R, Chan K. Validation of a new automatic edge detection algorithm in the measurement of left ventricular ejection fraction by comparing with radionuclide angiography and a combined echo-Doppler method. 1993 Can J Cardiol 1993;9(Suppl E).
  • Yvorchuk K, Sochowski R, Chan K. Does multiplane imaging improve Doppler examination in transesophageal echocardiography? 1993 Can J Cardiol 1993;9(Suppl E)Abs 25:25.
  • Yvorchuk K, Chan K. Discordance between chest wall fractures and cardiovascular trauma in victims of motor vehicle accidents and their effects on outcome. 1993 Can J Cardiol 1993;9(Suppl E).
  • Yvorchuk K, Sochowski R, Chan K. Distribution of mobile aortic masses and their relationship to aortic atherosclerosis: A transesophageal echocardiographic study of the thoracic aorta. Can J Cardiol 1993;9(suppl E)Abs 121:95E.
  • Yvorchuk K, Sochowski R, Chan K. A prospective randomised study to compare multiplane with biplane transesophageal echocardiography. 1993 Can J Cardiol 1993;9(Suppl E)Abs 118;94E.
  • Sochowski R, Yvorchuk K, Rates M, Yang Y. Chan K. Dobutamine and dipyridamole stress echocardiography in patients with a low incidence of severe coronary artery disease. Can J Cardiol 1993;9(suppl E)Abs 246:126E.
  • Chan K, Giannoccaro P, Taylor D, Sochowski R. Comparison of Valsalva manoeuvre with cough in the detection of patient foramen ovale by transesophageal contrast echocardiography. Clinical and Investigative Medicine 1993; Suppl to Vol 16(4) Abs 55:B14.
  • Cohen J, Chan K, Jaarsma W, Starling M, Armstrong W. Arbutamine echocardiography: Sensitivity and specificity with a new stress agent delivered by a computerised closed loop system. J Am Coll Card 1994;1A:732-1:120A. Abs
  • Chan K, Sochowski R. Conservative medical treatment can be appropriate in the management of perivalvular abscess: Diagnosis and followup by transesophageal echocardiography. J Am Coll Card 1994;1A:931-50:322A. Abs
  • Yvorchuk K, Sochowski R, Chan K. A prospective randomised study to compare multiplane with biplane transesophageal echocardiography in anatomic visualisation and Doppler assessment of cardiac structures. J Am Coll Card 1994:1A:793-1:386A. Abs
  • Yvorchuk K, Sochowski R, Chan K. Distribution of mobile aortic masses and their relationship to aortic atherosclerosis: A transesophageal echocardiographic study of the thoracic aorta. J Am Coll Card 1994;1A:808-3:442A. Abs
  • Sochowski R, Mount H, Chan K. Comparison of transthoracic with transesophageal echocardiography in patients with suspected embolic visual system disorders. J Am Soc Echo 1994;7(3)(2):S5(6-III) Abs
  • Chan K, Auclair F, Moher D, Laupacis A, Hendry P (for the CATIE investigators). Role of Aspirin in the prevention of embolism in infective endocarditis: Rationale, design and feasibility data of the Canadian Aspirin trial in infective endocarditis. Circulation 1994;90(4) 0646:1-121 Abs.
  • Yvorchuk K, Sochowski R, Chan K. Sonicated Albumin in exercise echocardiography: technique and feasibility of a novel approach to enhance endocardial border visualisation. J Am Coll Cardiol. 1995;26;936-91:159A.
  • Yvorchuk K, Sochowski R, Chan K. Transesophageal echocardiographic findings of non-traumatic aortic rupture with or without associated dissection. J Am Coll Cardiol 1995;26;753-3:229A.
  • Danter WR, Yvorchuk KJ, Chan K. Artificial neural network categorisation of cardiac ejection fraction based on echocardiographic data. Circulation 1995;92(8);3507:1-730.
  • Kim HH, Tam JW. Chan K. UFO in atria and pulmonary veins: Is it a real phenomenon? Circulation 1995;92(8);2569:1-538.
  • Chan K for the SPAF Invesitgators. Transesophageal echocardiographic risk factors for stroke are related to gender and age: Observations from the SPAF III study. Circulation 1995;92(8);1346:1-283.
  • Tam JW, Kim HH, Chan K, Antecol D, Yvorchuk K. Low dose Dobutamine echocardiography in predicting outcome of valve surgery for aortic or mitral regurgitation. Circulation 1995;92(8):1971:1-393.
  • Chan K. for CATIE Investigators. Transesophageal echocardiogaphy obviates the need for transthoracic echocardiography in patients with infective endocarditis. Can J Cardiol 1995;11(supple E)121:99E.
  • Tam JW, Kim HH, Keon WJ, Brais M, Bedard P, Chan K. Miniroot technique is superior to subcoronary technique in homograft aortic valve replacement. Can J Cardiol 1995;11(suppl E)103:94E.
  • Tam JW, Kim HH, Chan K, Antecol D, Yvorchuk K. Low dose Dobutamine echocardiography in predicting outcome of valve surgery for aortic or mitral regurgitation. Can J Cardiol 1995;11(suppl E)119:98E.
  • Tan P, Kim HH, Martin H, Tam JW, Chan K, Baird MG, Ascah KJ, Sochowski RA, Higginson L. Echo is superior to EKG in assessing prognosis in acute inferior MI. Can J Cardiol 1995;11(Suppl E)23:74E.
  • Kim HH, Tam JW, Chan K. UFO in atrial and pulmonary veins: Is it a real phenomenon? Can J Cardiol 1995;11(Suppl E)103:87E.
  • Kim H, Tam JW, Yvorchuk K, Davies RA, Chan K. Effect of imaging plane and LV function on Albunex echocardiography. J Can Cardiol 1995;11(suppl E)115:97E.
  • Huntington K, Chan K. Is there an inheritance pattern in bicuspid aortic valve? J Am Coll Cardiol. 1996;27(2)(Supple A);1034-112:397A.
  • Chan K, Auclair F, for the CATIE Investigators. Clinical spectrum of infective endocarditis in the 1990’s data from the Canadian Aspirin trial in Infective Endocarditis (CATIE). Clin and Invest Med 1996;19(4)S57(331).
  • Huntington, Chan K. A prospective echocardiographic study to assess familial clustering of congenital bicuspid aortic valve. Clin and Invest Med 1996:19(4):S55(405)
  • Chan K, for the SPAF Investigators. A prospective study to assess transesophageal echocardiographic (TEE) findings in the prediction of stroke in high risk patients with atrial fibrillation. Can J Cardiol 1996;12(Suppl E):121E (169)
  • Tam JW, Masters R, Burwash I, Kim H. Chan K. Is there a need for concomitant aortic valve replacement in patients with mild aortic stenosis undergoing CABG? Can J Cardiol 1996:12(Suppl E):92E(55).
  • Hynes MS, Tam JW, Burwash IG, Chan K. What is the significance of blunted pulmonary venous flow in the detection of mitral regurgitation or left ventricular abnormalities in ambulatory patients? Can J Cardiol 1996;12(Suppl E):79E(3).
  • Burwash IG, Tam JW, Teskey RJ, Dickinson A, Chan K. Discrepancy between gorlin equation and continuity equation aortic valve area relates to transvalvular flow in patients with valvular aortic stenosis. Can J Cardiol 1996;12(Suppl E):80E(6).
  • Burwash IG, Francis MI, Bryson CM, McNutt BJ, Raymond R, Chan K. Effect of inotropic stimulation on Doppler-echo indices of stenosis severity in patients with valvular aortic stenosis. Can J Cardiol 1996;12(Suppl E):80E(4).
  • Chan K for the SPAF Investigators. A prospective study to assess transesophageal echocardiographic (TEE) findings in the prediction of stroke in high risk patients with atrial fibrillation. Circulation 1996;94(8)(Suppl 1):1-216.
  • Tam JW, Masters R, Burwash I, Kim H, Chan K. Is there a need for concomitant aortic valve replacement in patients with mild aortic stenosis undergoing CABG? Circulation 1996;94(8)(Suppl 1):1-292.
  • Burwash IG, Francis MI, Bryson CM, McNutt BJ, Raymond R, Chan K. Effect of inotropic stimulation on Doppler-echo indices of stenosis severity in patients with valvular aortic stenosis. Circulation 1996;94(8)(suppl 1):1-30.
  • Tam JW, Burwash IG, Ascah KJ, Baird MG, Chan KL. Multiplane transesophageal imaging: What is the price for improved spatial orientation? A review of 2916 consecutive studies. J Am Coll Cardiol. 1997;29:338A.
  • Chan K, Cujec B, Dumesnil J, Saniflippo A, Jue J, Turek M, Robinson T. Clinical characteristics and outcome of infective endocarditis with no vegetation on echocardiography. Can J Cardiol 1997;13:99C.
  • Chan K, Veinot J. How good is echocardiography in the detection of congenital bicuspid aortic valve? Clinical Investigative Medicine 1997;20(4):S6.
  • Chan K, for MATIE Investigators. Comparison of culture negative with culture positive endocarditis: Presentation, echocardiographic findings and outcome. Clinical Investigative Medicine 1997;20(4):S56.
  • Burwash I, Hay K, Chan K, Are flow-mediated changes in doppler-echo aortic valve area due to changes in left ventricular outflow tract spatial velocity profiles? Can J Cardiol 1997 13;C:99C.
  • Huq N, Chan K, Mayhew A, Ascah K, Baird M, Burwash I Optimal Doppler Assessment of Aortic Stenosis: Where to interrogate and for how long? Can J Cardiol 1997 13;C:100C.
  • Chan K, Cujec B, Dumesnil J, Sanfilippo A, Jue J, Turek M, Robinson T, Dufour C, Wang D, Embolism in infective endocarditis: risk factors, clinical characteristics and outcome. Can J Cardiol 1997 13;C:120C.
  • Ghani M, Burwash I, Chan K, Are atherosclerosis risk factors relevant in the development of aortic stenosis in congenital bicuspid aortic valve? Can J Cardiol 1997 13;C:121C.
  • Chan K, Cujec B, Dumesnil J, Sanfilippo A, Jue J, Turek M, Robinson T. Embolism in infective endocarditis – risk factors, clinical characteristics and outcome. Circulation 1997;96:I-317.
  • Chan K, Cujec B, Dumesnil J, Sanfilippo A, Jue J, Turek M, Robinson T. Clinical characteristics and outcome of infective endocarditis with no vegetation on echocardiography. J Am Soc Echocardiogr 1998;11:559.
  • Aggarwal SG, Tang ASL, Chan K. Biventricular pacing reduces mitral regurgitation in patients with heart failure and bundle branch block. Can J Cardiol 1998;14 (Suppl F):125F.
  • Ramadan, Masters RG, Chan K. Surgical management and long term outcome in patients with dilated aortic root and surgical aortic valve disease. Can J Cardiol 1998;14 (Suppl F):126F.
  • Ghani M, Burwash I, Chan K. Cholesterol and triglyceride levels in congenital bicuspid aortic valve: risk factors for the development of aortic stenosis. Can J Cardiol 1998;14 (Suppl F):132F.
  • Ghani M, Huq N, Burwash I, Chan K. Comparison between digital and videotape recordings of echocardiograms in anatomic visualization and diagnostic performance. Can J Cardiol 1998;14 (Suppl F):134F.
  • Aggarwal SG, Huq NM, Chan K, Burwash I. A practical model for doppler assessment of aortic stenosis severity: accuracy of a limited window approach. Can J Cardiol 1998;14 (Suppl F):106F.
  • Burwash IG, Hay KM, Chan K. Does valve morphology affect flow dependence of aortic valve area in valvular aortic stenosis? Can J Cardiol 1998;14 (Suppl F):106F.
  • Burwash IG, Hay KM, Chan K. Symptomatic status in valvular aortic stenosis: relationship to measures of stenosis severity, systolic function, diastolic function and left ventricular remodelling. Can J Cardiol 1998;14 (Suppl F):125F.
  • Fagan SM, Chan K, Tang ASL. Echocardiographic assessment of the effect of multisite pacing on myocardial performance and contraction asynchrony in heart failure patients with conduction delay. Can J Cardiol 1999;15(Suppl D):120D.
  • Beauchesne LM, Chan K, Burwash IG. Temporal variations in effective orifice area during ejection in patients with valvular aortic stenosis. Can J Cardiol 1999;15(Suppl D):120D.
  • Chan K, Berger PB, Blackshear J, Pearce L, Halperin J. Significance of homocysteine in patients with atrial fibrillation: findings from the stroke prevention in atrial fibrillation (SPAF III). Can J Cardiol 1999;15(Suppl D):183D.
  • Aggarwal SG, Huq NM, Chan K, Burwash IG. A practical model for Doppler assessment of aortic stenosis severity: accuracy of a limited window approach. J Am Soc Echocardiogr 1999;12(5):353.
  • Burwash IG, Hay KM, Chan KL. Symptomatic status in valvular aortic stenosis: relationship to measures of stenosis severity, systolic function, diastolic function and left ventricular remodelling. J Am Soc Echocardiogr 1999;12(5):369.
  • Chan KL. Long term outcome of surgical versus medical treatment in endocarditis complicated by perivalvular abscess. J Am Coll Cardiol 2000;35(Suppl A):529A.
  • Beauchesne LM, Chan KL, Burwash IG. Temporal variations in effective orifice area during ejection: relationship to hemodynamic severity in patients with valvular aortic stenosis. J Am Coll Cardiol 2000;35(Suppl A):535A.
  • Chan KL for the MATIE Investigators. Gender differences in predisposing factors for endocarditis: Findings of the multicentre aspirin study in infective endocarditis (MATIE) study. Can J Cardiol 2000;16(Suppl B):61B.
  • Chan KL, Dumesnil J, Cujec B, Sanfilippo A, Jue J, Turek M, Robinson T for the MATIE Investigators. A prospective study to assess the effect of aspirin on outcome of endocarditis. Can J Cardiol 2000;16(Suppl F):131F.
  • Burwash IG, Hay KM, Chan KL. Does symptomatic status relate to valve compliance in valvular aortic stenosis? Can J Cardiol 2000;16(Suppl F):160F.
  • Beauchesne LM, Chan KL, Burwash IG. Temporal variations in effective orifice area during ejection in patients with aortic stenosis: relationship to symptomatic status. Can J Cardiol 2000;16(Suppl F):160F.
  • Tardif JC, Dore A, Chan KL, Fagan S, Honos G, Marcotte F, Yu E, Siu S, Dumesnil J, Arsenault M, Koilpillai C, D’Onofrio F. Evaluation of Levovist-enhanced stress echocardiography in patients with suspected coronary artery disease: results of a Canadian multicentre study. Can J Cardiol 2000;16(Suppl F):200F.
  • Chan KL, Dumesnil J, Cujec B, Sanfilippo A, Jue J, Turek, Robinson T for the MATIE Investigators. Predictors of mortality in 560 patients with infective endocarditis. Can J Cardiol 2000;16(Suppl F):205F.
  • Chan KL, Dumesnil J, Cujec B, Sanfilippo A, Jue J, Turek M, Robinson T for the MATIE Investigators. Gender differences in predisposing factors for endocarditis: findings of the multicentre aspirin study in infective endocarditis (MATIE) study. Can J Cardiol 2000;16(Suppl F):232F.
  • Beauchesne L, Chan KL, Ascah K, Burwash I. Implications of symptomatic hemodynamic, and EKG changes during exercise testing in patients with aortic stenosis:relationship to coronary artery disease. JACC Feb 2001;37(Suppl A):158A.
  • Chan KL, Dumesnil J, Cujec B, Sanfillipo A, Jue J, Robinson T. Predictors of Mortality in 560 Patients with infective endocarditis: Findings of the multicentre Aspirin trial in infective endocarditis (MATIE) study. JACC Feb 2001;37(Suppl A):474A.
  • Chan KL, Dumesnil JG, Cujec B, Sanfilippo AJ, Jue J, Turek MA, Robinson TI. Effect of Aspirin on the progression of vegetation in infective endocarditis. Can J Cardiol Sept 2001;17 (Suppl C)150C.
  • Burwash, IG, Beauchesne LM, Hay KM, Chan KL. Can dynamic changes in aortic valve area during ejection predict valve area response to dobutamine testing in valvular aortic stenosis? Can J Cardiol 2001;17(Suppl C):151C.
  • Ramadan F, Chan KL, Can echocardiographic features predict progression in adult patients with discrete subaortic stenosis? Can J Cardiol, Sept 2001; 17(Suppl C):224C
  • Chan KL, Prevalence and clinical correlates of increased intraventricular velocities in ambulatory elderly subjects. Can J Cardiol, Sept 2001; 17(Suppl C):224C
  • Kinsara A, Chan KL, Ramadan F, Malcolm. Prevalence and clinical correlates of increased intraventricular velocities in ambulatory elderly subjects. JACC April 2002; 39(Suppl B):371B.
  • Chan KL, Bulman D, Hunter A. Is endothelial nitric oxide synthase gene associated with congenital bicuspid aortic valve in human? JACC April 2002, 39 (Suppl B):387B.
  • Chan KL, Dumesnil JG, Cujec B, Sanfilippo AJ, Jue J, Turek MA, Robinson TI. A prospective survey to assess the impact of echocardiography on the management of infective endocarditis. CJC Sept 2002;18 (Suppl B):146B.
  • Chan KL, Scoggan KA, Zou R, Hunter AGW, Bulman D. Is endothelial nitric oxide synthase gene associated with congenital bicuspid aortic valve in human? CJC Sept 2002;18 (Suppl B):229B.
  • Tesson F, Bilinska Z, Veinot, JP, Chan KL, et al. Contrasted molecular mechanisms associated with lamin A/C mutations in end-stage dilated cardiomyopathy patients. Circulation Oct 2003;108:IV-83.
  • Mercier LA, Houde C, Chan KL, Ducharme A, Juneau M, Dore A. Losartan does not improve exercise capacity in asymptomatic adults with a systemic morphologic right ventricle. Circulation Oct 2003;108:IV-642.
  • Chan KL, Lui X, Ascah K, Beauchesne L, Burwash I. Comparison of real-time 3-D echocardiography with conventional 2-D echocardiography in the assessment of structural heart disease. Can J Cardiol Oct 2003;19 (suppl A):174A.
  • Little SH, Chan KL, Burwash IG. Effect of blood pressure on the doppler-echo assessment of stenosis severity in patients with valvular aortic stenosis. Can J Cardiol Oct 2004;20 (suppl D):144D.
  • Al-Faleh H, Ruel M, Chan KL, Beauchesne LM, Lam BK, Mesana T, Burwash IG. Effect of prosthetic-patient mismatch after aortic valve replacement on left ventricular remodelling in patients with normal and impaired preoperative left ventricular function. Can J Cardiol Oct 2004;20 (suppl D):164D.
  • Al-Faleh H, Burwash IG, Chan KL, Masters RG, Mesana TG, Ruel M. Prosthesis-patient mismatch after aortic valve replacement: impact of preoperative left ventricular function on clinical outcomes. Can J Cardiol Oct 2004;20 (suppl D):200-201D.
  • Al-Faleh H, Ruel M, Chan KL, Beauchesne LM, Lam BK, Mesana T, Burwash IG. Effect of prosthetic-patient mismatch after aortic valve replacement on left ventricular remodelling in patients with normal and impaired preoperative left ventricular function. Circulation Oct 26 2004;100(17):III-549.
  • Al-Faleh H, Burwash IG, Chan KL, Masters RG, Mesana TG, Ruel M. Prosthesis-patient mismatch after aortic valve replacement: impact of preoperative left ventricular function on clinical outcomes. Circulation Oct 26 2004;100(17):III-709.
  • Salehian O, Chan KL, Ascah K, Burwash IG, Beauchesne LM. Systolic velocity of the tricuspid annulus predicts peak oxygen consumption in patients with repaired Tetralogy of fallot. A tissue doppler imaging study. Can J Cardiol Oct 2005;21(Supple C):834.
  • Chan KL, Tam J, Sochowski R, Dumesnil J, Jue J, Honos G, Joyner C, Koipillai C, Teo K. A randomized study to assess effect of cholesterol lowering on progression of aortic stenosis: rationale, design and baseline characteristics of the first 100 subjects. Can J Cardiol Oct 2005;21(Supple C):253C.
  • Salehian O, Chan KL, Beauchesne LM. Left ventricular myocardial performance index is abnormal in patients with repaired tetralogy of fallot. Can J Cardiol Oct 2005; 21(Supple C):248C.
  • Salehian, O, Chan KL, Burwash IG, Beauchesne LM. Left ventricular myocardial performance index is abnormal in patients with repaired Tetralogy of Fallot. JACC Feb 21, 2006; 47 (4) (Suppl A): 248A.
  • Salehian O, Dennie C, Morin J, Chan KL, Burwash IG, Beauchesne L. REF : 4629 Right Ventricular Tissue Doppler Indices in Patients with Repaired Tetralogy of Fallot. Comparison to Cardiac Magnetic Resonance Imaging.
  • Salehian O, Dennie CJ, Morin J, Chan KL, Burwash IG, Beauchesne LM. Right ventricular tissue doppler indices in patients with repaired Tetralogy of fallot. Comparison to cardiac magnetic resonance imaging. Can J Cardiol. Oct 2006;22 (Suppl D):48D.
  • Chan KL, Tam J, Sochowski R, Dumesnil JG, Giannoccaro P, Jue J, Pandey S, Joyner C, Teo K. Influence of gender on left ventricular and left atrial adaptation to aortic stenosis: the ASTRONOMER study. Can J Cardiol. Oct 2006;22(Suppl D):218D.
  • Chan K, Tam J, Sochowski R, Dumesnil JG, Giannoccaro P, Jue J, Pandey S, Joyner C, Teo K. Determinants of aortic valve calcification in aortic stenosis: insights from the Astronomer study. Can J Cardiol. Oct 2007;23(Suppl C):284-85C.
  • Jassal DS, Tam JW, Sochowski RA, Dumesnil JG, Giannoccaro PJ, Jue J, Pandey AS, Joyner CD, Teo KK, Chan KL. Clinical usefulness of tissue doppler imaging in patients with mild to moderate aortic stenosis: a substudy of the aortic stenosis progression observation measuring effects of rosuvastatin (Astronomer) study. Can J Cardiol. Oct 2007;23(Suppl C):250-51C.
  • Tam JW, Jassal DS, Sochowski RA, Dumesnil JG, Giannoccaro PJ, Jue J, Pandey AS, Joyner CD, Teo KK, Chan KL. Effect of aortic valve morphology on aortic valvular calcification and mitral annular calcification in patients with mild to moderate aortic stenosis. Can J Cardiol. Oct 2007;23(Suppl C):251-52C.
  • Law A, Burwash IG, Beauchesne LM, Ascah KJ, Turek M, Labinaz M, Marquis J-F, Chan K. Predictors of residual shunting post percutaneous patent foramen ovale closure. Can J Cardiol. Oct 2007;23(Suppl C):273C.
  • Chan KL, Tam J, Sochowski R, Dumesnil JG, Giannoccaro P, Jue J, Pandey S, Joyner C, Teo K. Abstract 2655: Correlates Of Aortic Valve Calcification In Aortic Stenosis: Insights From The Astronomer Study. Circulation, Oct 2007; 116: II_588.
  • Burwash IG, Little SH, Chan KL. Author’s reply. Heart 2008 Apr;94(4):508.
  • Tam J, Jassal DS, Chan KL, Predicting Subclinical Heart Failure in patients with Mild to Moderate Aortic Stenosis: A Substudy of the ASTRONOMER study, European Journal of Heart Failure 2008: 7 (1): 46.
  • Bhagirath KM, Jassal DS, Tam JW, Sochowski R, Dumesnil J, Giannoccaro P, Jue J, Pandey AS, Joyner CD, Teo KK, Chan KL. Can bicuspid valve morphology predict the pattern of aortic root dilatation? A substudy of the aortic stenosis progression observation measuring effects of rosuvastatin (ASTRONOMER) study. Can J Cardiol. Oct 2008;24(Suppl E):188E.

BOOK CHAPTERS

  • Non-Invasive Assessment of Coronary Artery Disease, Chapter 2 in Advance in the Diagnosis and Treatment of Coronary Artery Disease. Editors: W.J. Keon, D.S. Beanlands, and E.M.Farrell. Publishers: Blackwell Scientific Publications, Inc. 1989
  • Transesophageal Echocardiography: Indications, Procedure, Image Planes and Doppler Flows. Chapter 1 in The Practice of Clinical Echocardiography: Transthoracic and Transesophageal Approaches, 2nd edition. Editor: Catherine Otto. Publishers: Harcourt Health Sciences (W.B. Saunders).
  • Johnson C, Chan KL. Role of transthoracic and transesophageal echocardiography in the management of endocarditis. In Endocarditis: Diagnosis and Management. Chan KL, Embil J, Eds.; Springer-Verlag London, 2006;79-103.
  • Salehian O, Chan KL. Systemic embolism in endocarditis: Incidence, risk factors, clinical significance, and treatment strategies. In Endocarditis: Diagnosis and Management. Chan KL, Embil J, Eds.; Springer-Verlag London, 2006;229-240.
  • Transesophageal Echocardiography: Indications, Procedure, Image Planes and Doppler Flows. Chapter 1 in The Practice of Clinical Echocardiography: Transthoracic and Transesophageal Approaches, 3nd edition. Editor: Catherine Otto. Publishers: Harcourt Health Sciences (W.B. Saunders).

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