Edwards, Jodi

Overview 

Jodi Edwards, PhD is a Scientist and Director of the Brain and Heart Nexus Research Program at the University of Ottawa Heart Institute and an Affiliate Investigator with the Clinical Epidemiology Research Program at the Ottawa Hospital Research Institute.

Background 

Dr. Edwards was born in Calgary, Alberta, Canada. In 2003, she received her MA in Linguistics from the University of Calgary, using functional neuroimaging and eye-movement monitoring techniques to explore the neural substrates of language comprehension in patients with speech deficits post-stroke. Dr. Edwards then worked as a Research Associate with the Functional MRI Research Teams at both the Hotchkiss Brain Institute in Calgary and the Brain Imaging Centre at the Douglas Hospital Research Centre in Montreal. 

In 2008, Dr. Edwards moved to Vancouver to pursue doctoral training in Clinical Epidemiology at the University of British Columbia. Her dissertation work focused on the identification of novel neurophysiological determinants of risk for recurrent stroke and other major cardiovascular events in individuals with a recent transient ischemic attack (TIA). This work was published in Stroke and in 2011, Dr. Edwards received the CIHR Institute of Neurosciences, Mental Health, and Addiction Brain Star Award for this contribution. 

In 2014, Dr. Edwards moved to Toronto to take a position as a postdoctoral fellow in the laboratory of Dr. Sandra Black in the Heart and Stroke Foundation (HSF) Canadian Partnership for Stroke Recovery at Sunnybrook Research Institute, where she continued research evaluating the contributions of novel cardiovascular risk factors to patient outcomes in high-risk populations. Dr. Edwards has held continuous salary funding from national agencies including CIHR and HSF throughout her training, she has published over 30 articles in leading peer-reviewed journals in her field, has given over 50 national and international conference presentations including 7 invited symposia, and has garnered national media coverage for her work. 

Dr. Edwards held consecutive terms as Chair of the National Training Associations for both the Canadian Stroke Network and Canadian Partnership for Stroke Recovery and she currently sits on the editorial board for the Journal of Alzheimer’s Disease. She is an active reviewer for numerous journals including Clinical Cardiology, the Journal of Human Hypertension, the International Journal of Stroke, BMC Neurology, the Journal of American Geriatrics, Neurobiology of Aging, and Alzheimer’s Research and Therapy, and is a current member of the working group for the 2018 HSF Stroke Report. Her research program is presently funded by grants from the Canadian Stroke Trials for Optimized Results and the Canadian Stroke Prevention Intervention Network.

Research & Clinical Interests 

Dr. Edwards research program utilizes clinical and administrative data from population-based databases to evaluate the independent and cumulative contributions of unexplored cardiac risk factors, including physiological changes associated with early cardiac remodelling, on clinical outcomes in individuals at high risk of stroke, atrial fibrillation, and cognitive decline.

The ultimate goal of Dr. Edwards’ research is to develop predictive tools to identify those at highest risk of adverse cardiovascular outcomes and extend the window for preventive management in this population.

Publications 

See current publications list at PubMed.

Key Publications

Edwards JD, Kapral MK, Fan, J. Swartz, R. (2017) High long-term mortality and morbidity in stable patients without early complications after stroke or TIA. CMAJ. Jul 24;189(29):E954-E961.

Edwards JD, Ramirez J, Callahan BL, Berezuk C, Lanctot K, Swardfager W, Strother S, Kiss A, Nestor S, Black SE. (2017). Antihypertensive treatment is associated with imaging markers of neurodegeneration and cognition: A propensity-weighted cohort analysis. Journal of Alzheimer’s Disease. 59(3):1113-1122.

Edwards JD. (2017). The importance of identifying early changes in cardiac structure and function for the prevention of cognitive impairment and dementia. Journal of Alzheimer’s Disease. 58(1):285-288.

Edwards JD, Kapral MK, Lindsay MP, Fang J, Swartz RH. (2017) Temporal trends in mortality and morbidity in patients with no early complications after stroke and transient ischemic attack. Journal of Stroke and Cerebrovascular Diseases. Jul;26(7):1641-1645.

Edwards JD, Koehoorn M, Boyd LA, Sobolev B, Levy AR. (2017). Diagnostic Accuracy of Transient Ischemic Attack from Physician Claims. Canadian Journal of Neurological Sciences. Jul;44(4):397-403.

Edwards JD, Kapral MK, Fan, J, Saposnik G, Gladstone, DJ. (2016). Underutilization of Ambulatory ECG Monitoring After Stroke and Transient Ischemic Attack. Missed Opportunities for Atrial Fibrillation Detection. Stroke. 47(8):1982-9.

Edwards JD, Jacova C, Sephery A, Pratt B, & Benavente OR. (2013). A Quantitative Systematic Review of Domain-Specific Cognitive Impairment in Lacunar Stroke. Neurology. Jan 15;80(3):315-22.

Edwards JD, Meehan SK, Levy AR, Teal PA, Linsdell MA, Boyd LA. (2011). Changes in intracortical excitability after transient ischemic attack are associated with ABCD2 score. Stroke. 42(3):728-33.

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